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Effects of long-term active immunization with the second extracellular loop of human β1- or β3-adrenoceptors in thoracic aorta and mesenteric arteries in Lewis rats

Autor: Laurence Dubreil, B. Jagu, Valérie Lalanne, Daniel Henrion, Chantal Thorin, Jean-Claude Desfontis, Gilles Toumaniantz, E. Montaudon, Lionel Martignat, Mohamed Yassine Mallem

Publikováno v: Vascular Pharmacology
Vascular Pharmacology, Elsevier, 2016, 87, pp.129-138. ⟨10.1016/j.vph.2016.09.004⟩

International audience; ObjectiveTo evaluate whether active immunization producing β1- or β3-antibodies (β1-ABs and β3-ABs) detected in sera of patients with dilated cardiomyopathies has deleterious effects on vascular reactivity in Lewis rat tho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce3184626bc7d23c0ade89d7db7f3f9a
https://doi.org/10.1016/j.vph.2016.09.004

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Transforming growth factor β receptor inhibition prevents ventricular fibrosis in a mouse model of progressive cardiac conduction disease

Autor: Cynthia Ore Cerpa, Christopher L.-H. Huang, Mickaël Derangeon, B. Jagu, Justine Patin, Jérôme Montnach, Isabelle Baró, Flavien Charpentier, Gilles Toumaniantz, Andrew A. Grace, William H. Colledge, Aurore Girardeau

Publikováno v: Cardiovascular Research
Cardiovascular Research, Oxford University Press (OUP), 2017, Equipe IIa, 113 (5), pp.464--474. ⟨10.1093/cvr/cvx026⟩

International audience; Aims: Loss-of-function mutations in SCN5A, the gene encoding NaV1.5 channel, have been associated with inherited progressive cardiac conduction disease (PCCD). We have proposed that Scn5a heterozygous knock-out (Scn5a+/-) mice

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d7bfccc84f98d17f0d13b722b9bd81f
https://hal.archives-ouvertes.fr/hal-01832149

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Effects of long-term active immunization with the second extracellular loop of human β

Autor: E, Montaudon, L, Dubreil, V, Lalanne, B, Jagu, G, Toumaniantz, C, Thorin, D, Henrion, J-C, Desfontis, L, Martignat, M Y, Mallem

Publikováno v: Vascular pharmacology. 87

To evaluate whether active immunization producing βLewis rats were immunized for 6months with peptidic sequences corresponding to the second extracellular loop of βThe immunizations producing functional βOur study shows that β

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::84a9b5ff65a2bafeaeea1e05df9528c8
https://pubmed.ncbi.nlm.nih.gov/27620808

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CO-20: Caractérisation de la cardiomyopathie associée à la lipodystrophie congénitale généralisée de Berardinelli-Seip

Autor: Bertrand Cariou, Michael Joubert, David Montaigne, Xavier Marechal, Xavier Prieur, Jocelyne Magré, B. Jagu, Gilles Toumaniantz, Bart Staels, Angela Tesse, C. Le May, L. Dollet

Publikováno v: Diabetes & Metabolism. 42:A6-A7

Introduction La lipodystrophie congenitale de Berardinelli-Seip (BSCL) est un syndrome rare caracterise par une absence generalisee de tissu adipeux, une insulino-resistance severe et une atteinte cardiaque encore mal caracterisee. Une des deux forme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::efffdf63a61e9d1cc6389f2f115bed30
https://doi.org/10.1016/s1262-3636(16)30038-6

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Identifying potential functional impact of mutations and polymorphisms: linking heart failure, increased risk of arrhythmias and sudden cardiac death

Autor: B. Jagu, Gilles Toumaniantz, Flavien Charpentier

Publikováno v: Frontiers in Physiology
Frontiers in Physiology, Vol 4 (2013)

Researchers and clinicians have discovered several important concepts regarding the mechanisms responsible for increased risk of arrhythmias, heart failure, and sudden cardiac death. One major step in defining the molecular basis of normal and abnorm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2426c3edef1053fce8684a71170a3c6d
http://europepmc.org/articles/PMC3778269

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277Study of the role of Scn5a in the occurrence of arrhythmic events during myocardial infarction and post-ischemic remodeling

Autor: T. Le Tourneau, Gilles Toumaniantz, B. Jagu, Flavien Charpentier

Publikováno v: Cardiovascular Research. 103:S50.1-S50

The sodium channel Nav1.5, encoded by the Scn5a gene, is responsible for the excitability and the conduction velocity of electrical impulses through the heart. Nav1.5 mutations are involved in rhythmic or structural pathologies. During the acute phas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::886750d04e043adced30d4f2879fc4c9
https://doi.org/10.1093/cvr/cvu085.1

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O39 Les souris déficientes en seipine sont un nouveau modèle de cardiomyopathie diabétique

Autor: Bertrand Cariou, Gilles Toumaniantz, L. Dollet, Jocelyne Magré, T. Le Tourneau, Xavier Prieur, Philippe Costet, M. Takahashi, B. Jagu

Publikováno v: Diabetes & Metabolism. 39:A10

Introduction La lipodystrophie congenitale de Berardinelli-Seip (BSCL) est un syndrome rare caracterise par une absence generalisee de tissu adipeux et une insulino-resistance severe. Les cardiomyopathies sont frequentes chez les patients atteints de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::75bd809f83cffb8e68b7bc39d2fb6dfd
https://doi.org/10.1016/s1262-3636(13)71651-3

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