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A histomorphometric study on the hepatoprotective effects of a green rooibos extract in a diet-induced obese rat model

Autor: D.L. Pereira, J.I. Layman, Nireshni Chellan, Sanet H. Kotzé, B. Huisamen

Publikováno v: Acta Histochemica. 121:646-656

Obesity, type two diabetes mellitus and insulin resistance are associated with increased oxidative stress and inflammation. Unfermented green rooibos is an aspalathin rich variant of traditional fermented rooibos (Aspalathus linearis) and has a high

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::243862e381acdc591e03c6c3991d3393
https://doi.org/10.1016/j.acthis.2019.05.008

Poster session 3Cell growth, differentiation and stem cells - Heart511The role of the endocannabinoid system in modelling muscular dystrophy cardiac disease with induced pluripotent stem cells.512An emerging role of T lymphocytes in cardiac regenerative processes in heart failure due to dilated cardiomyopathy513Canonical wnt signaling reverses the ‘aged/senescent’ human endogenous cardiac stem cell phenotype514Hippo signalling modulates survival of human induced pluripotent stem cell-derived cardiomyocytes515Biocompatibility of mesenchymal stem cells with a spider silk matrix and its potential use as scaffold for cardiac tissue regeneration516A snapshot of genome-wide transcription in human induced pluripotent stem cell-derived hepatocyte-like cells (iPSC-HLCs)517Can NOS/sGC/cGK1 pathway trigger the differentiation and maturation of mouse embryonic stem cells (ESCs)?518Introduction of external Ik1 to human-induced pluripotent stem cell-derived cardiomyocytes via Ik1-expressing HEK293519Cell therapy of the heart studied using adult myocardial slices in vitro520Enhancement of the paracrine potential of human adipose derived stem cells when cultured as spheroid bodies521Mechanosensitivity of cardiomyocyte progenitor cells: the strain response in 2D and 3D environments522The effect of the vascular-like network on the maturation of the human induced pluripotent stem cell derived cardiomyocytes.Transcriptional control and RNA species - Heart525Gene expression regulation in heart failure: from pathobiology to bioinformatics526Human transcriptome in idiopathic dilated cardiomyopathy - a novel high throughput screening527A high-throghput approach unveils putative miRNA-mediated mitochondria-targeted cardioprotective circuits activated by T3 in the post ischemia reperfusion setting528The effect of uraemia on the expression of miR-212/132 and the calcineurin pathway in the rat heartCytokines and cellular inflammation - Heart531Lack of growth differentiation factor 15 aggravates adverse cardiac remodeling upon pressure-overload in mice532Blocking heteromerization of platelet chemokines ccl5 and cxcl4 reduces inflammation and preserves heart function after myocardial infarction533Is there an association between low-dose aspirin use and clinical outcome in HFPEF? Implications of modulating monocyte function and inflammatory mediator release534N-terminal truncated intracellular matrix metalloproteinase-2 expression in diabetic heart.535Expression of CD39 and CD73 on peripheral T-cell subsets in calcific aortic stenosis536Mast cells in the atrial myocardium of patients with atrial fibrillation: a comparison with patients in sinus rhythm539Characteristics of the inflammatory response in patients with coronary artery disease and arterial hypertension540Pro-inflammatory cytokines as cardiovascular events predictors in rheumatoid arthritis and asymptomatic atherosclerosis541Characterization of FVB/N murinic bone marrow-derived macrophage polarization into M1 and M2 phenotypes542The biological expression and thoracic anterior pain syndromeSignal transduction - Heart545The association of heat shock protein 90 and TGFbeta receptor I is involved in collagen production during cardiac remodelling in aortic-banded mice546Loss of the inhibitory GalphaO protein in the rostral ventrolateral medulla of the brainstem leads to abnormalities in cardiovascular reflexes and altered ventricular excitablitiy547Selenoprotein P regulates pressure overload-induced cardiac remodeling548Study of adenylyl cyclase activity in erythrocyte membranes in patients with chronic heart failure549Direct thrombin inhibitors inhibit atrial myocardium hypertrophy in a rat model of heart failure and atrial remodeling550Tissue factor / FVIIa transactivates the IGF-1R by a Src-dependent phosphorylation of caveolin-1551Notch signaling is differently altered in endothelial and smooth muscle cells of ascending aortic aneurysm patients552Frizzled 5 expression is essential for endothelial proliferation and migration553Modulation of vascular function and ROS production by novel synthetic benzopyran analogues in diabetes mellitusExtracellular matrix and fibrosis - Heart556Cardiac fibroblasts as inflammatory supporter cells trigger cardiac inflammation in heart failure557A role for galectin-3 in calcific aortic valve stenosis558Omega-3 polyunsaturated fatty acids- can they decrease risk for ventricular fibrillation?559Serum levels of elastin derived peptides and circulating elastin-antielastin immune complexes in sera of patients with coronary artery disease560Endocardial fibroelastosis is secondary to hemodynamic alterations in the chick model of hypoplastic left heart syndrome561Dynamics of serum levels of matrix metalloproteinases in primary anterior STEMI patients564Deletion of the alpha-7 nicotinic acetylcholine receptor changes the vascular remodeling induced by transverse aortic constriction in mice.565Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veinsIon channels, ion exchangers and cellular electrophysiology - Heart568Microtubule-associated protein RP/EB family member 1 modulates sodium channel trafficking and cardiac conduction569Investigation of electrophysiological abnormalities in a rabbit athlete's heart model570Upregulation of expression of multiple genes in the atrioventricular node of streptozotocin-induced diabetic rat571miR-1 as a regulator of sinoatrial rhythm in endurance training adaptation572Selective sodium-calcium exchanger inhibition reduces myocardial dysfunction associated with hypokalaemia and ventricular fibrillation573Effect of racemic and levo-methadone on action potential of human ventricular cardiomyocytes574Acute temperature effects on the chick embryonic heart functionVasculogenesis, angiogenesis and arteriogenesis577Clinical improvement and enhanced collateral vessel growth after monocyte transplantation in mice578The role of HIF-1 alpha, VEGF and obstructive sleep apnoea in the development of coronary collateral circulation579Initiating cardiac repair with a trans-coronary sinus catheter intervention in an ischemia/reperfusion porcine animal model580Early adaptation of pre-existing collaterals after acute arteriolar and venular microocclusion: an in vivo study in chick chorioallantoic membraneEndothelium583EDH-type responses to the activator of potassium KCa2.3 and KCa3.1 channels SKA-31 in the small mesenteric artery from spontaneously hypertensive rats584The peculiarities of endothelial dysfunction in patients with chronic renocardial syndrome585Endothelial dysfunction, atherosclerosis of the carotid arteries and level of leptin in patient with coronary heart disease in combination with hepatic steatosis depend from body mass index.586Role of non-coding RNAs in thoracic aortic aneurysm associated with bicuspid aortic valve587Cigarette smoke extract abrogates atheroprotective effects of high laminar flow on endothelial function588The prognostic value of anti-connective tissue antibodies in coronary heart disease and asymptomatic atherosclerosis589Novel potential properties of bioactive peptides from spanish dry-cured ham on the endothelium.Lipids592Intermediate density lipoprotein is associated with monocyte subset distribution in patients with stable atherosclerosis593The characteristics of dyslipidemia in rheumatoid arthritisAtherosclerosis596Macrophages differentiated in vitro are heterogeneous: morphological and functional profile in patients with coronary artery disease597Palmitoylethanolamide promotes anti-inflammatory phenotype of macrophages and attenuates plaque formation in ApoE-/- mice598Amiodarone versus esmolol in the perioperative period: an in vitro study of coronary artery bypass grafts599BMPRII signaling of fibrocytes, a mesenchymal progenitor cell population, is increased in STEMI and dyslipidemia600The characteristics of atherogenesis and systemic inflammation in rheumatoid arthritis601Role of adenosine-to-inosine RNA editing in human atherosclerosis602Presence of bacterial DNA in thrombus aspirates of patients with myocardial infarction603Novel E-selectin binding polymers reduce atherosclerotic lesions in ApoE(-/-) mice604Differential expression of the plasminogen receptor Plg-RKT in monocyte and macrophage subsets - possible functional consequences in atherogenesis605Apelin-13 treatment enhances the stability of atherosclerotic plaques606Mast cells are increased in the media of coronary lesions in patients with myocardial infarction and favor atherosclerotic plaque instability607Association of neutrophil to lymphocyte ratio with presence of isolated coronary artery ectasiaCalcium fluxes and excitation-contraction coupling610The coxsackie- and adenovirus receptor (CAR) regulates calcium homeostasis in the developing heart611HMW-AGEs application acutely reduces ICaL in adult cardiomyocytes612Measuring electrical conductibility of cardiac T-tubular systems613Postnatal development of cardiac excitation-contraction coupling in rats614Role of altered Ca2+ homeostasis during adverse cardiac remodeling after ischemia/reperfusion615Experimental study of sarcoplasmic reticulum dysfunction and energetic metabolism in failing myocardium associated with diabetes mellitusHibernation, stunning and preconditioning618Volatile anesthetic preconditioning attenuates ischemic-reperfusion injury in type II diabetic patients undergoing on-pump heart surgery619The effect of early and delayed phase of remote ischemic preconditioning on ischemia-reperfusion injury in the isolated hearts of healthy and diabetic rats620Post-conditioning with 1668-thioate leads to attenuation of the inflammatory response and remodeling with less fibrosis and better left ventricular function in a murine model of myocardial infarction621Maturation-related changes in response to ischemia-reperfusion injury and in effects of classical ischemic preconditioning and remote preconditioningMitochondria and energetics624Phase changes in myocardial mitochondrial respiration caused by hypoxic preconditioning or periodic hypoxic training625Desmin mutations depress mitochondrial metabolism626Methylene blue modulates mitochondrial function and monoamine oxidases-related ROS production in diabetic rat hearts627Doxorubicin modulates the real-time oxygen consumption rate of freshly isolated adult rat and human ventricular cardiomyocytesCardiomyopathies and fibrosis630Effects of genetic or pharmacologic inhibition of the ubiquitin/proteasome system on myocardial proteostasis and cardiac function631Suppression of Wnt signalling in a desmoglein-2 transgenic mouse model for arrhythmogenic cardiomyopathy632Cold-induced cardiac hypertrophy is reversed after thermo-neutral deacclimatization633CD45 is a sensitive marker to diagnose lymphocytic myocarditis in endomyocardial biopsies of living patients and in autopsies634Atrial epicardial adipose tissue derives from epicardial progenitors635Caloric restriction ameliorates cardiac function, sympathetic cardiac innervation and beta-adrenergic receptor signaling in an experimental model of post-ischemic heart failure636High fat diet improves cardiac remodelling and function after extensive myocardial infarction in mice637Epigenetic therapy reduces cardiac hypertrophy in murine models of heart failure638Imbalance of the VHL/HIF signaling in WT1+ Epicardial Progenitors results in coronary vascular defects, fibrosis and cardiac hypertrophy639Diastolic dysfunction is the first stage of the developing heart failure640Colchicine aggravates coxsackievirus B3 infection in miceArterial and pulmonary hypertension642Osteopontin as a marker of pulmonary hypertension in patients with coronary heart disease combined with chronic obstructive pulmonary disease643Myocardial dynamic stiffness is increased in experimental pulmonary hypertension partly due to incomplete relaxation644Hypotensive effect of quercetin is possibly mediated by down-regulation of immunotroteasome subunits in aorta of spontaneously hypertensive rats645Urocortin-2 improves right ventricular function and attenuates experimental pulmonary arterial hypertension646A preclinical evaluation of the anti-hypertensive properties of an aqueous extract of Agathosma (Buchu)Biomarkers648The adiponectin level in hypertensive females with rheumatoid arthritis and its relationship with subclinical atherosclerosis649Markers for identification of renal dysfunction in the patients with chronic heart failure650cardio-hepatic syndromes in chronic heart failure: North Africa profile651To study other biomarkers that assess during myocardial infarction652Interconnections of apelin levels with parameters of lipid metabolism in hypertension patients653Plasma proteomics in hypertension: prediction and follow-up of albuminuria during chronic renin-angiotensin system suppression654Soluble RAGE levels in plasma of patients with cerebrovascular events

Autor: C Falcone, M Baldan Martin, K Yushko, SUMIYA Tserendavaa, I Nassiri, U Kamilova, O Sirenko, B Huisamen, R Adao, S Goncharov, WJ Van Der Laarse, O Hetman, RW Emmens, VI Kapelko, I Menendez-Montes, A Russell-Hallinan, O Tsoref, C De Lucia, N Suffee, L Woudstra, C Ruperez, A Lorenzon, T Zaglia, JM Elder, OANA M Duicu, N Smolina, VI Portnichenko, L Griecsova, GD Duerr, M Murarikova, T Sosorburam, D Kondrat'eva, A Dominguez, A Zahradnikova, M Scardigli, D Deluyker, C Matthaeus, MNS Shaaban, WW Fuijkschot, RA Fraga-Silva, B Thaler, P Pinon, K Stellos, J Starodubova, T Hofbauer, D Ozkaramanli Gur, P Rinne, S Fiorelli, KA Krychtiuk, SM Martinez Sanchez, AR Babaeva, H Morawietz, A Bhattachariya, M Grechanyk, A Maslenko, M Kloza, W Xiang, C Nebert, MA Abela, M Wagner, F Vostarek, L Diolaiuti, J Prorok, A Gualdoni, FC Howarth, P Kui, V Portero, M Lynch, FP Neto, V Ryabov, D Sedmera, A Nikolov, B Bacova, R Sadaba, D Lindner, D Muntean, MM Brandt, DA Kostina, M Aberg, C Jumeau, S Usui, R Ang, RG Garcia, D Munteanu, M DE C Santuchi, NP Korzhenkov, NA Musikhina, T Kucera, A Golovkin, H W Lee, N Glezeva, T Vajen, SCA De Jager, M Sarkozy, F Forini, A Chaloupka, C Schiano, M Pekkanen-Mattila, NAM Bax, C Sid-Otmane, F Perbellini, A Costa, V Spinelli, LE Viiri, L Fuentes, G Foldes, FC Lewis, T Kulikova, A Gowran, V Vigorelli, P Nigro, G Pompilio, O Stepanova, M Valikhov, A Samko, V Masenko, S Tereschenko, T Teoh, E Domenjo-Vila, T Theologou, M Field, W Awad, M Yasin, B Nadal-Ginard, GM Ellison-Hughes, N Hellen, O Vittay, SE Harding, L Gomez-Cid, ME Fernandez-Santos, S Suarez-Sancho, V Plasencia, A Climent, R Sanz-Ruiz, M Hedhammar, F Atienza, F Fernandez-Aviles, M Kiamehr, M Oittinen, KM Viiri, M Kaikkonen, K Aalto-Setala, A Laurino, L Sartiani, A Vona, M Zanardelli, E Cerbai, P Failli, MP Hortigon-Vinagre, M Van Der Heyden, FL Burton, GL Smith, S Watson, M Scigliano, S Tkach, S Alayoubi, CM Terracciano, HQ Ly, A Mauretti, MH Van Marion, MC Van Turnhout, DWJ Van Der Schaft, CM Sahlgren, MJ Goumans, CVC Bouten, H Vuorenpaa, K Penttinen, R Sarkanen, T Ylikomi, T Heinonen, V Grimaldi, M Aprile, R Esposito, C Maiello, A Soricelli, V Colantuoni, V Costa, A Ciccodicola, C Napoli, GC Rowe, K Johnson, ZP Arany, F Del Monte, R D'aurizio, C Kusmic, G Nicolini, M Baumgart, M Groth, N Ucciferri, G Iervasi, L Pitto, M Pipicz, R Gaspar, A Siska, I Foldesi, K Kiss, P Bencsik, T Thum, S Batkai, T Csont, JJ Haan, L Bosch, MAD Brans, SM Van De Weg, JC Deddens, SJ Lee, JPG Sluijter, G Pasterkamp, I Werner, D Projahn, M Staudt, A Curaj, TT Soenmez, S Simsekyilmaz, TM Hackeng, P Von Hundelshausen, RR Koenen, C Weber, EA Liehn, M Santos-Martinez, C Medina, C Watson, K Mcdonald, J Gilmer, M Ledwidge, SH Song, MY Lee, MH Park, JC Choi, JH Ahn, JS Park, JH Oh, JH Choi, HC Lee, KS Cha, TJ Hong, I Kudryavtsev, M Serebryakova, A Malashicheva, A Shishkova, E Zhiduleva, O Moiseeva, M Durisova, M Blaha, V Melenovsky, J Pirk, J Kautzner, TI Petelina, LI Gapon, EA Gorbatenko, YV Potolinskaya, EV Arkhipova, KS Solodenkova, MA Osadchuk, MF Dutra, FCB Oliveira, MM Silva, DG Passos-Silva, R Goncalves, RAS Santos, RF Da Silva, CM Gavrilescu, CM Paraschiv, P Manea, LC Strat, JMG Gomez, D Merino, MA Hurle, JF Nistal, A Aires, AL Cortajarena, AV Villar, J Abramowitz, L Birnbaumer, AV Gourine, A Tinker, M Takamura, S Takashima, O Inoue, H Misu, T Takamura, S Kaneko, TOHIRA Alieva, N Mougenot, M Dufilho, S Hatem, A Siegbahn, AS Kostina, VE Uspensky, OM Moiseeva, AA Kostareva, AB Malashicheva, CGM Van Dijk, I Chrifi, MC Verhaar, DJ Duncker, C Cheng, A Sturza, A Petrus, O Duicu, L Kiss, M Danila, I Baczko, N Jost, F Gotzhein, J Schon, M Schwarzl, S Hinrichs, S Blankenberg, U Volker, E Hammer, D Westermann, E Martinez-Martinez, V Arrieta, A Fernandez-Celis, L Jimenez-Alfaro, A Melero, V Alvarez-Asiain, V Cachofeiro, N Lopez-Andres, N Tribulova, G Wallukat, V Knezl, J Radosinska, M Barancik, I Tsinlikov, I Tsinlikova, G Nicoloff, A Blazhev, Z Pesevski, A Kvasilova, T Stopkova, A Eckhardt, C M Buffinton, O Nanka, M Kercheva, T Suslova, A Gusakova, T Ryabova, V Markov, R Karpov, H Seemann, TC Alcantara, SG Fonseca, J Barallobre-Barreiro, R Oklu, M Fava, F Baig, X Yin, H Albadawi, M Jahangiri, J Stoughton, M Mayr, SP Podliesna, CCV Veerman, AOV Verkerk, MK Klerk, EML Lodder, IM Mengarelli, CRB Bezzina, CAR Remme, H Takacs, A Polyak, N Morvay, I Lepran, L Tiszlavicz, N Nagy, B Ordog, A Farkas, T Forster, A Varro, AS Farkas, P Jayaprakash, K Parekh, Z Ferdous, M Oz, H Dobrzynski, TE Adrian, S Landi, M Bonzanni, A D'souza, M Boyett, A Bucchi, M Baruscotti, D Difrancesco, A Barbuti, K Oravecz, T Hezso, J Levijoki, P Pollesello, T Koskelainen, L Otsomaa, A S Farkas, JGY Papp, A Toth, K Acsai, L Dini, L Mazzoni, A Mugelli, J Svatunkova, C Deffge, C Baer, S Weinert, RC Braun-Dullaeus, J Herold, AC Cassar, GZ Zahra, EP Pllaha, PD Dingli, SM Montefort, RGX Xuereb, T Aschacher, B Messner, E Eichmair, W Mohl, B Reglin, W Rong, B Nitzsche, M Maibier, P Guimaraes, A Ruggeri, TW Secomb, AR Pries, M Baranowska-Kuczko, O Karpinska, M Kusaczuk, B Malinowska, H Kozlowska, N Demikhova, L Vynnychenko, O Prykhodko, N Grechanyk, A Kuryata, KA Cottrill, L Du, HM Bjorck, S Maleki, A Franco-Cereceda, SY Chan, P Eriksson, S Giebe, N Cockcroft, K Hewitt, M Brux, C Brunssen, AA Tarasov, SI Davidov, EA Reznikova, A Tapia Abellan, D Angosto Bazarra, P Pelegrin Vivancos, S Montoro Garcia, SP Kastl, T Pongratz, G Goliasch, L Gaspar, G Maurer, K Huber, E Dostal, S Pfaffenberger, S Oravec, J Wojta, WS Speidl, I Osipova, I Sopotova, S Eligini, N Cosentino, G Marenzi, E Tremoli, M Rami, L Ring, S Steffens, O Gur, S Gurkan, A Mangold, T Scherz, A Panzenboeck, N Staier, H Heidari, J Mueller, IM Lang, A Gatsiou, K Stamatelopoulos, L Perisic, D John, FF Lunella, U Hedin, A Zeiher, S Dimmeler, L Nunez, R Moure, G Marron-Linares, X Flores, G Aldama, J Salgado, R Calvino, M Tomas, G Bou, N Vazquez, M Hermida-Prieto, JM Vazquez-Rodriguez, U Amit, N Landa, D Kain, D Tyomkin, A David, J Leor, PJ Hohensinner, J Baumgartner, N Baik, LA Miles, H Seeman, F Montecucco, AR Da Silva, FP Costa-Fraga, L Anguenot, FP Mach, N Stergiopulos, K Kupreishvili, ABA Vonk, YM Smulders, VWM Van Hinsbergh, W Stooker, HWM Niessen, PAJ Krijnen, MM Ashmawy, MA Salama, MZ Elamrosy, R Juettner, F G Rathjen, V Bito, C Crocini, C Ferrantini, T Gabbrielli, L Silvestri, R Coppini, C Tesi, C Poggesi, FS Pavone, L Sacconi, K Mackova, I Zahradnik, I Diaz, E Sanchez De Rojas De Pedro, K Hmadcha, E Calderon Sanchez, JP Benitah, AM Gomez, T Smani, A Ordonez, SA Afanasiev, MV Egorova, SV Popov, P Wu Qing, X Cheng, S Carnicka, D Pancza, M Jasova, I Kancirova, M Ferko, T Ravingerova, S Wu, M Schneider, V Marggraf, L Verfuerth, S Frede, O Boehm, O Dewald, G Baumgarten, S-C Kim, V Farkasova, I Gablovsky, I Bernatova, V Nosar, A Portnychenko, T Drevytska, I Mankovska, V Gogvadze, T Sejersen, A Kostareva, A Wolf, A Privistirescu, P O ' Gara, JL Sanchez-Alonso, AR Lyon, V Prando, N Pianca, F Lo Verso, G Milan, P Pesce, M Sandri, M Mongillo, G Beffagna, G Poloni, E Dazzo, P Sabatelli, R Doliana, R Polishchuk, D Carnevale, G Lembo, P Bonaldo, P Braghetta, A Rampazzo, M Cairo, M Giralt, F Villarroya, A Planavila, PS Biesbroek, RWE Emmens, LJM Juffermans, AC Van Der Wall, AC Van Rossum, JWM Niessen, T Moor Morris, G Dilanian, P Farahmand, M Puceat, G Gambino, L Petraglia, A Elia, K Komici, GD Femminella, ML D'amico, G Pagano, A Cannavo, D Liccardo, WJ Koch, M Nolano, D Leosco, N Ferrara, G Rengo, R Neary, L Shiels, J Baugh, B Palacios, B Escobar, AV Alonso, G Guzman, J Ruiz-Cabello, LJ Jimenez-Borreguero, S Martin-Puig, VL Lakomkin, EV Lukoshkova, AA Abramov, VV Gramovich, ON Vyborov, VV Ermishkin, NA Undrovinas, VP Shirinsky, BJ Smilde, G Fong Hing, D Wouters, S Zeerleder, JL Murk, SM Van Ham, S Heymans, O Krakhmalova, D Van Groen, SJP Bogaards, I Schalij, GV Portnichenko, LV Tumanovska, YV Goshovska, TU Lapikova-Bryhinska, VS Nagibin, VE Dosenko, P Mendes-Ferreira, C Maia-Rocha, D Santos-Ribeiro, F Potus, S Breuils-Bonnet, S Provencher, S Bonnet, M Rademaker, AF Leite-Moreira, C Bras-Silva, J Lopes, O Kuryata, T Lusynets, I Alikulov, M Nourddine, L Azzouzi, R Habbal, ODKHUU Enkhtaivan, ZORIGO Shagdar, MUNKHZ Malchinkhuu, MUNLHZ Malchinkhuu, S Koval, T Starchenko, L Mourino-Alvarez, L Gonzalez-Calero, T Sastre-Oliva, JA Lopez, J Vazquez, G Alvarez-Llamas, LUIS M Ruilope, F De La Cuesta, MG Barderas, S Bozzini, A D'angelo, G Pelissero

Publikováno v: Cardiovascular Research. 111:S92-S116

Purpose Cardiomyocytes progenitor cells (CMPCs) are a candidate cell source for cardiac regenerative therapy. To assess their full potential for cardiac regeneration, it is essential to know if and how CMPCs sense and respond to the three-dimensional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::345cc7e90701ae62a4c64b6195ad3a33
https://doi.org/10.1093/cvr/cvw150

AMP kinase activation and glut4 translocation in isolated cardiomyocytes

Autor: I, Webster, S O, Friedrich, A, Lochner, B, Huisamen

Publikováno v: Cardiovascular Journal of Africa

Summary Activation of AMP-activated protein kinase (AMPK) results in glucose transporter 4 (GLUT4) translocation from the cytosol to the cell membrane, and glucose uptake in the skeletal muscles. This increased activation of AMPK can be stimulated by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::37265aaa3b730e9d2fbfa9ec74da5546
https://pubmed.ncbi.nlm.nih.gov/20532430

Signalling pathways activated by glucagon-like peptide-1 (7-36) amide in the rat heart and their role in protection against ischaemia

Autor: B, Huisamen, S, Genade, A, Lochner

Publikováno v: Cardiovascular Journal of Africa

Summary Summary Glucagon-like peptide-1 is an incretin hormone proposed to have insulinomimetic effects on peripheral insulin-sensitive tissue. We examined these effects on the heart by using isolated, perfused rat hearts and adult ventricular myocyt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::86169104c85d20534ad33058f9873ac5
https://pubmed.ncbi.nlm.nih.gov/18516352