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Concentrations in serum and distribution in tissue of free and liposomal amphotericin B in rats during continuous intralipid infusion

Autor: Gabriel Lopez-Berestein, V B Grossie, Kishor M. Wasan

Publikováno v: Antimicrobial Agents and Chemotherapy. 38:2224-2226

The influences of Intralipid (IL) and 0.45% normal-saline infusions on the concentration in serum and distribution in tissue of amphotericin B (AmpB) and liposomal amphotericin B (L-AmpB) in rats were compared. In animals receiving a continuous IL in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf56c125ed0ecc31a1aaaa5c8957360
https://doi.org/10.1128/aac.38.9.2224

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Temporal expression of tumor necrosis factor-alpha and nitric oxide synthase 2 in rat small intestine after endotoxin

Autor: R, Arya, V B, Grossie, N W, Weisbrodt, M, Lai, D, Mailman, F, Moody

Publikováno v: Digestive diseases and sciences. 45(4)

Temporal changes in tumor necrosis factor-alpha (TNF-alpha) and nitric oxide synthase 2 (NOS 2) were evaluated in segments of duodenum, jejunum, and ileum removed from male Sprague-Dawley rats 30, 60, 120, 180, and 240 min after lipopolysaccharide (L

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::955ff0eb787c82c15e567422e96200d9
https://pubmed.ncbi.nlm.nih.gov/10759245

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Reduced tissue ornithine increases the cytotoxicity of difluoromethylornithine

Autor: V B, Grossie, K, Nishioka

Publikováno v: Anticancer research. 16(6B)

Polyamines are low molecular weight cations that are essential for the growth of all cells. The polyamine inhibitor difluoromethylornithine (DFMO) will decrease tumor growth when administered parenterally; thrombocytopenia is the major dose-limiting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d9e2f1b22b637708e0a9ad646209cba1
https://pubmed.ncbi.nlm.nih.gov/9042249

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Nutritional support for adaptation to radiation-induced suppression of mucosal immunity in the intestine of the rat

Autor: Y, Harari, V B, Grossie, G A, Castro

Publikováno v: Radiation research. 145(6)

Appropriate enteral nutrition provided immediately after injury or trauma to the gastrointestinal tract may limit or reverse damage to the mucosal barrier. In this regard, diets containing amino acids, such as arginine and glutamine, or fish oil have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d6069996f049471955fd8b0fbf5d979f
https://pubmed.ncbi.nlm.nih.gov/8643836

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Effect of intralipid infusion on serum high- and low-density lipoprotein cholesterol, lecithin:cholesterol acyltransferase, and lipoprotein lipase in tumor-bearing rats

Autor: V. B. Grossie, K. M. Wasan

Publikováno v: Experientia. 51(3)

We compared the effects of 0.45% normal saline (NS), 5% Intralipid® (IL), and 16.7% glucose (Glu) infusions on total serum triglycerides and cholesterol, serum high-(HDL-c) and low-density lipoprotein cholesterol (LDL-c), and activity of serum lecit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e19824d42b1d1a0a10a321e20e45de4
https://pubmed.ncbi.nlm.nih.gov/7698286

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Effects of intralipid infusion on rat serum lipoproteins

Autor: Kishor M. Wasan, Gabriel Lopez-Berestein, V B Grossie

Publikováno v: Laboratory animals. 28(2)

The purpose of this investigation was to study the effects of continuous Intralipid® infusions on serum HDL and LDL levels in the rat. Male Fischer 344 rats were infused continuously via central venous catheter with 10% Intralipid® for 96 h and 5,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2368ca1f9774ee2759c106d5120067f9
https://pubmed.ncbi.nlm.nih.gov/8035564

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Glutamine stability in biological tissues evaluated by fluorometric analysis

Autor: V B, Grossie, J, Yick, M, Alpeter, T C, Welbourne, D M, Ota

Publikováno v: Clinical chemistry. 39(6)

Although glutamine has been considered unstable during storage and therefore difficult to quantitate, recent results suggest this amino acid is stable at low pH ranges. We evaluated the stability of glutamine in plasma and tissue extracts, using fluo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a3154610dcd9c3d889531072334ae02b
https://pubmed.ncbi.nlm.nih.gov/8504538

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