Zobrazeno 1 - 10
of 56
pro vyhledávání: '"B, Gröschel"'
Publikováno v:
DMW - Deutsche Medizinische Wochenschrift. 126:1249-1254
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 20:1433-1437
Continuous cultivation of T-lymphoid C8166 cells in the presence of pharmacological relevant concentration of cytarabine (Ara-C) results in significantly decreased expression of CD4 and CXCR4 molecules, the major cellular receptor and co-receptor of
Publikováno v:
Infection. 28:209-213
Cellular cytoplasmatic thymidine kinase 1 (TK1) catalyzes the intracellular phosphorylation of anti-HIV-1 nucleoside analogs zidovudine (AZT) and stavudine (d4T) to the corresponding monophosphate form. In HIV-1-infected patients, treated with combin
Publikováno v:
Journal of Clinical Immunology. 20:117-122
90K is a secreted serum glycoprotein with immune stimulatory activity. In this study, 90K plasma levels were determined by an enzyme-linked immunosorbent assay in 18 HIV-1-infected children and 10 uninfected control children. 90K levels in HIV-1-infe
Publikováno v:
Nucleosides and Nucleotides. 18:933-936
Cytotoxic and antiretroviral activity of cycloSal-d4TMP derivatives were tested in a new AZT-resistant H9 cell subline (H9rAZT250). The results showed, that cycloSal-d4TMP derivatives overcame resistance of HIV-1 to d4T in H9rAZT250 cells, which exer
Publikováno v:
Nucleosides and Nucleotides. 18:921-926
A 2',3'-dideoxycytidine (ddC)-resistant T-lymphoid cell line (MOLT-4/8rddC250), in which deoxycytidine kinase (dCK) gene-expression was decreased when compared with parental cells, has been selected. Cytotoxic and antiretroviral activity of ddC and 3
Publikováno v:
Antiviral Chemistry and Chemotherapy. 8:343-352
Human T lymphoid MOLT4/8 cells were grown continuously for more than 2 years in a medium containing 3′-azido-2′,3′-dideoxythymidine (zidovudine; AZT) at a concentration of 250 μM. These cells, designated MOLT-4/8rAZT250, were used to test the
Autor:
B. Gröschel, Jaroslav Cinatl, Bernard Weber, Elmar Jaeckel, Leo C. Groenen, Erik De Clercq, G. Gross, Stephen Locarnini, Jean-Claude Schmit, Ralf Bartenschlager, Jens-Owe Vogel, Wolfgang H. Caselmann, Martin Scholz, Michael Alt, Angeline Bartholomeusz, Jindrich Cinatl, Wolfram H. Gerlich, Michael P. Manns, Stefan Eisenhardt, Peter Wutzler, Hans W. Doerr, Jr. Cinatl J.
Publikováno v:
Intervirology. 40:I-IV
Publikováno v:
Antiviral research. 53(2)
The biological evaluation of mononucleotide prodrugs (pronucleotides) of various nucleoside reverse transcriptase inhibitors (NRTIs) such as zidovudine (AZT), zalcitabine (ddC) and lamivudine (3TC) was reported in human T-lymphoid MOLT-4/8 cells whic
Publikováno v:
Deutsche medizinische Wochenschrift (1946). 126(44)