Zobrazeno 1 - 10 of 223 pro vyhledávání: '"B, Danielsen"'
1
Akademický článek
Cationic oligonucleotide derivatives and conjugates: A favorable approach for enhanced DNA and RNA targeting oligonucleotides
Autor: Mathias B. Danielsen, Jesper Wengel
Publikováno v: Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 1828-1848 (2021)
Antisense oligonucleotides (ASOs) have the ability of binding to endogenous nucleic acid targets, thereby inhibiting the gene expression. Although ASOs have great potential in the treatment of many diseases, the search for favorable toxicity profiles
Externí odkaz: https://doaj.org/article/1b7504243dad401e8ba68390a09d57d8
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2
Cationic oligonucleotide derivatives and conjugates: A favorable approach for enhanced DNA and RNA targeting oligonucleotides
Autor: Jesper Wengel, Mathias B. Danielsen
Publikováno v: Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 1828-1848 (2021)
Danielsen, M B & Wengel, J 2021, ' Cationic oligonucleotide derivatives and conjugates : A favorable approach for enhanced DNA and RNA targeting oligonucleotides ', Beilstein Journal of Organic Chemistry, vol. 17, pp. 1828-1848 . https://doi.org/10.3762/bjoc.17.125
Beilstein Journal of Organic Chemistry
Antisense oligonucleotides (ASOs) have the ability of binding to endogenous nucleic acid targets, thereby inhibiting the gene expression. Although ASOs have great potential in the treatment of many diseases, the search for favorable toxicity profiles
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::505ce1f1d0bed89122f9bec96980b431
https://doaj.org/article/1b7504243dad401e8ba68390a09d57d8
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3
Evaluation of Gene Expression Knock-Down by Chemically and Structurally Modified Gapmer Antisense Oligonucleotides
Autor: Jolanta Lisowiec‐Wąchnicka, Mathias B. Danielsen, Eugenie Abi Nader, Per T. Jørgensen, Jesper Wengel, Anna Pasternak
Publikováno v: Chembiochem : a European journal of chemical biology. 23(15)
We analyzed the effect of modified nucleotides within gapmer antisense oligonucleotides on RNase H mediated gene silencing. Additionally, short hairpins were introduced into antisense oligonucleotides as structural motifs, and their influence on biol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67d0427e597e47dbae1cb59fc4e62993
https://pubmed.ncbi.nlm.nih.gov/35675170
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4
Akademický článek
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5
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6
Social inequality in tooth loss: separate and joint effects of household income and dental visits
Autor: M, Hach, L B, Christensen, T, Lange, U A, Hvidtfeldt, B, Danielsen, F, Diderichsen, M, Osler, E, Prescott, I, Andersen
Publikováno v: Community dental health. 38(4)
The aim of the study was to investigate the separate and joint effects of household income and dental visits on tooth loss.Participants from the Social Inequality in Cancer Cohort (SIC) were followed in registers for household income (2000), dental v
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cd0c2d24c7bf5845c4c1925fa24db43f
https://pubmed.ncbi.nlm.nih.gov/34185443
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7
Polyamine‐Functionalized 2′‐Amino‐LNA in Oligonucleotides:Facile Synthesis of New Monomers and High‐Affinity Binding towards ssDNA and dsDNA
Autor: Niels Johan Christensen, Chenguang Lou, Knud J. Jensen, Jesper Wengel, Per T. Jørgensen, Mathias B. Danielsen
Publikováno v: Danielsen, M B, Christensen, N J, Jørgensen, P T, Jensen, K J, Wengel, J & Lou, C 2021, ' Polyamine-Functionalized 2′-Amino-LNA in Oligonucleotides : Facile Synthesis of New Monomers and High-Affinity Binding towards ssDNA and dsDNA ', Chemistry: A European Journal, vol. 27, no. 4, pp. 1416-1422 . https://doi.org/10.1002/chem.202004495
Danielsen, M B, Christensen, N J, Jørgensen, P T, Jensen, K J, Wengel, J & Lou, C 2021, ' Polyamine-Functionalized 2′-Amino-LNA in Oligonucleotides : Facile Synthesis of New Monomers and High-Affinity Binding towards ssDNA and dsDNA ', Chemistry-A European Journal, vol. 27, no. 4, pp. 1416-1422 . https://doi.org/10.1002/chem.202004495
Attachment of cationic moieties to oligonucleotides (ONs) promises not only to increase the binding affinity of antisense ONs by reducing charge repulsion between the two negatively charged strands of a duplex, but also to augment their in vivo stabi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acafae1eb3e7bb21a15c28964221b965
https://curis.ku.dk/ws/files/334664969/Polyamine_functionalized_2_10.pdf
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8
Offshore power generation with carbon capture and storage to decarbonise mainland electricity and offshore oil and gas installations: A techno-economic analysis
Autor: B. Danielsen, Til Kristian Vrana, Ailo Aasen, Per Eilif Wahl, R. Dreux, Rahul Anantharaman, Simon Roussanaly, G. Neji, A. Sødal, Jana P. Jakobsen, L. Heme-De-Lacotte
Publikováno v: Applied Energy
his study investigates the techno-economic potential of offshore power generation from natural gas with carbon capture and storage to reduce the climate impact of mainland electricity and the offshore oil and gas industry. This potential is assessed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce0262c8b00f1968af15cf2f6c3f0b49
https://hdl.handle.net/11250/2582427
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9
Akademický článek
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