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pro vyhledávání: '"B, Csóka"'
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Publikováno v:
Genomics. 48:63-70
We recently cloned and expressed the major hyaluronidase activity from human plasma, HYAL1, and found that the protein is 40% identical to the testicular hyaluronidase, PH-20. The HYAL1 mRNA sequence was used in a homology search of the mouse databas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce2e46f603e9e0f721b1a1ffb39f48ca
https://doi.org/10.1006/geno.1997.5158
https://doi.org/10.1006/geno.1997.5158
Publikováno v:
FEBS Letters. 417:307-310
We recently cloned the major hyaluronidase of human plasma, which we termed HYAL1. All hyaluronidase activity could be purified from human urine on an anti-HYAL1 monoclonal antibody column. However, urine contains two hyaluronidases of 57 kDa and 45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ed4a9cc799b3eff63e778193ff1a51
https://doi.org/10.1016/s0014-5793(97)01309-4
https://doi.org/10.1016/s0014-5793(97)01309-4
Publikováno v:
Biochemical and Biophysical Research Communications. 236:10-15
Hyaluronidase was purified from human plasma using Triton X-114 phase extractions and ion-exchange chromatography. Monoclonal antibodies generated against the purified protein by a novel screening assay were utilized to isolate homogeneous enzyme for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce810711a9f14f78a45685481fb3ce25
https://doi.org/10.1006/bbrc.1997.6773
https://doi.org/10.1006/bbrc.1997.6773
Publikováno v:
British Journal of Dermatology. 142:226-233
Hyaluronic acid (HA), a high molecular weight glycosaminoglycan of the extracellular matrix involved in growth, inflammation and wound healing, also contributes to the hydration and plastic properties of skin. Several drug and cosmetic formulations c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1a57f497a0cdcad406c2a9007020ee6
https://doi.org/10.1046/j.1365-2133.2000.03289.x
https://doi.org/10.1046/j.1365-2133.2000.03289.x
Publikováno v:
Trends in Glycoscience and Glycotechnology. 8:419-434
ヒアルロニダーゼは最近まで説明することなど必要ないと考えられていた酵素群である。これらの酵素の基質であるヒアルロナンは、徐々に重要性が増し、今や細胞の運動性、傷害治癒
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b990f68de41c17d7d35359c5e2d6494e
https://doi.org/10.4052/tigg.8.419
https://doi.org/10.4052/tigg.8.419
Autor:
Tony B. Csóka, Robert S. Stern
Publikováno v:
ChemInform. 30
Eukaryotic hyaluronidases are widely distributed, but until recently the only vertebrate enzyme to be cloned was the sperm-specific enzyme, PH20. We have now purified the hyaluronidase of human plasma. The identical enzyme, as well as a second proteo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa109619e001a884e9267ea0f8496e3f
https://doi.org/10.1002/chin.199930320
https://doi.org/10.1002/chin.199930320
Akademický článek
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Autor:
J M, Adams, L T, Difazio, R H, Rolandelli, J J, Luján, Gy, Haskó, B, Csóka, Zs, Selmeczy, Z H, Németh
Publikováno v:
Acta physiologica Hungarica. 96(1)
The transcription factor HIF-1 is one of the principal mediators of homeostasis in human tissues exposed to hypoxia. It is implicated in virtually every process of rapid gene expression in response to low oxygen levels. The most common causes of tiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::52528da73e6fe1af606a0b88b37e729e
https://pubmed.ncbi.nlm.nih.gov/19264039
https://pubmed.ncbi.nlm.nih.gov/19264039
Publikováno v:
Invasionmetastasis. 17(6)
Hyaluronidases are broadly distributed enzymes with varying substrate specificities, a wide range of pH optima, and different catalytic mechanisms. They may be used by organisms to invade one another. Hyaluronidases have also been invoked as mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c1b6ea4401249e73aab685238ebb6c4e
https://pubmed.ncbi.nlm.nih.gov/9949289
https://pubmed.ncbi.nlm.nih.gov/9949289