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Phase 1 trial of ralimetinib (LY2228820) with radiotherapy plus concomitant temozolomide in the treatment of newly diagnosed glioblastoma

Autor: R. Bellini, Julian Biau, Ioana Molnar, Catherine Godfraind, D. Stefan, Emmanuel Chautard, Fabrice Kwiatkowski, Xavier Durando, M. Boone, B. Chauffert, Emilie Thivat, Damien Richard, C. Bourgne, Pierre Verrelle, Lucie Karayan-Tapon, S. Levesque

Publikováno v: Radiotherapy & Oncology
Radiotherapy & Oncology, 2021, 154 (227-234), ⟨10.1016/j.radonc.2020.09.036⟩
Radiotherapy and Oncology
Radiotherapy and Oncology, Elsevier, 2021, 154 (227-234), ⟨10.1016/j.radonc.2020.09.036⟩

International audience; Background and purpose: This phase 1 trial aimed to determine the maximum tolerated dose (MTD; primary objective) of a p38-MAPK inhibitor, ralimetinib, with radiotherapy (RT) and chemotherapy (TMZ), in the treatment of newly d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b529f921dea12bb2600d15ea662f892
https://hal.science/hal-02954534/document

Dépistage des cancers bronchopulmonaires par tomodensitométrie thoracique à faible dose dans la Somme

Autor: B. Chauffert, M A Auquier, O. Leleu, P. Berna, A. Dubreuil, Vincent Jounieaux, B. Trancart, O. Carre, V. Petigny

Publikováno v: Revue des Maladies Respiratoires. 34:262-267

Resume Rationnel Cette etude de faisabilite se propose d’experimenter dans le departement de la Somme (France) un depistage annuel du cancer du poumon par scanner thoracique basse irradiation. Elle repond au premier objectif du troisieme plan cance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1b14321e91a8dc92760299c6806c3405
https://doi.org/10.1016/j.rmr.2016.08.003

Incidence and survival rates for adult malignant neuro-epithelial brain tumors in the Somme county (France): A retrospective, population-based study from 2003 to 2013

Autor: D. Bello Roufai, Pascal Caillet, E. Trecherel, O. Ganry, B. Chauffert, B. Lapôtre-Ledoux, L. Bauchet

Publikováno v: Journal of Cancer Policy
Journal of Cancer Policy, Elsevier, 2018, 15, Part A, pp.5-9. ⟨10.1016/j.jcpo.2017.11.001⟩

International audience; Aims: To describe the incidence and survival rates for neuro-epithelial primary brain tumors (NPBTs) in adults in the Somme county between 2003 and 2013. Methods: By analyzing the Somme Cancer Registry, we calculated the age-s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af2b1d6ac0501bdf9154a79c342084f
https://hal-u-picardie.archives-ouvertes.fr/hal-03598675/file/1-s2.0-S2213538317300565-main.pdf

P14.92 Study of Glutaminergic and Glutamatergic Metabolism in 1H-MRS Monovoxel in the Most Aggressive Part of 62 Glioblastoma Before and After 18 months Treatment

Autor: Mathieu Boone, S Boussida, Michel Lefranc, J Chombar, Jean-Marc Constans, A. Coutte, N. Deleval, B Chauffert, Z Saidak, A. Heintz

Publikováno v: Neuro Oncol

BACKGROUND To study the relationships between glutaminergic metabolism (Glx/tCr), tumor proliferation (tCho/tCr) and other metabolic activities in patients with glioblastoma (GBM). MATERIAL AND METHODS Patients: 62 patients with glioblastoma, all hav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fe18d9641d56db09e4174a4d835db90
https://doi.org/10.1093/neuonc/noz126.327