Zobrazeno 1 - 10
of 104
pro vyhledávání: '"B, Brzozowski"'
Autor:
J, Zagajewski, D, Wojcik-Grzybek, B, Brzozowski, J, Majka, M, Magierowski, W, Placha, M, Lasota, P M, Laidler, T, Brzozowski
Publikováno v:
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 72(6)
Melatonin (N-acetyl-5-methoxytryptamine) is an indoleamine synthesized in vertebrates mainly in the pineal gland, and is known to be involved mainly in thermoregulation and control of the circadian rhythm. That indoleamine can affect the auto-, para-
Publikováno v:
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 71(4)
Crohn's disease (CD) is a chronic inflammatory disease of unknown etiology that covers the entire digestive tract and occurs with periods of remission and clinical exacerbation. CD is most common in North America and Europe, but its incidence is risi
Akademický článek
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Publikováno v:
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 70(1)
Galectins are lectins involved in physiological processes such as cell proliferation, apoptosis and migration, immune responses, inflammation, signalling, and angiogenesis. This study assessed the serum levels of galectin-3 (Gal-3) and galectin-3 (Ga
Akademický článek
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Publikováno v:
Electrochimica Acta. 174:625-629
Electrolyte optimization for both best performance and low use of materials is described in this paper. Electrochemical performance and material utility are reported to achieve the goal of optimal combinations of salt concentration and solvent ratios
Autor:
David B. Brzozowski, Ronald L. Hanson, Michael K. Wong, Dana L Cazzulino, Steven L. Goldberg, Thomas P. Tully, Truc Chi Vu, Ramesh N. Patel, William L. Parker, Olav Lyngberg
Publikováno v:
Advanced Synthesis & Catalysis. 349:1369-1378
The non-proteinogenic amino acid 2-(3-hydroxy-1-adamantyl)-(2S)-aminoethanoic acid [2, (S)-3-hydroxyadamantylglycine], is a key intermediate required for the synthesis of Saxagliptin, a dipeptidyl peptidase IV inhibitor under development for treatmen
Autor:
Ronald L. Hanson, Ramesh N. Patel, William L. Parker, David B. Brzozowski, Atul S. Kotnis, Mark Liu, Thomas P. Tully
Publikováno v:
Tetrahedron: Asymmetry. 16:2711-2716
6-Hydroxybuspirone is an active metabolite of the antianxiety drug buspirone. The (R)- and (S)-enantiomers of 6-hydroxybuspirone were prepared using an enzymatic resolution process. l -Amino acid acylase from Aspergillus melleus (Amano Acylase 30000)
Publikováno v:
Advanced Synthesis & Catalysis. 345:830-834
A new enzymatic process for the enantioselective cleavage of N-benzyloxycarbonyl (Cbz) groups from protected amino acids and related compounds has been developed. The Cbz-deprotecting enzyme was isolated from cell extracts of Sphingomonas paucimobili
Autor:
Robert J. Johnston, Ramesh N. Patel, Ronald L. Hanson, Jeffrey M. Howell, Amit Banerjee, Rapheal Ko, Mary-Jo Donovan, Animesh Goswami, Dana L Cazzulino, Steven L. Goldberg, David B. Brzozowski, Venkata B. Nanduri, Thomas P. Tully
Publikováno v:
Journal of Industrial Microbiology and Biotechnology. 30:252-259
There has been an increasing awareness of the enormous potential of microorganisms and enzymes for the transformation of synthetic chemicals with high chemo-, regio- and enatioselective manner. Chiral intermediates are in high demand by pharmaceutica