Zobrazeno 1 - 10
of 84
pro vyhledávání: '"B, Bolstad"'
Autor:
Lt. Steven B. Bolstad USN
In the 1990s the United States Armed Forces will be asked by its leaders to do more with less. This represents a significant turn from the policies of the last decade. During World War Two the German Army operated effectively under similar policy con
Publikováno v:
Eukaryotic Cell. 8:483-486
Trimethoprim, an antifolate commonly prescribed in combination with sulfamethoxazole, potently inhibits several prokaryotic species of dihydrofolate reductase (DHFR). However, several eukaryotic pathogenic organisms are resistant to trimethoprim, pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da88c84303a0045cb3375c2327a5b594
https://doi.org/10.1128/ec.00298-08
https://doi.org/10.1128/ec.00298-08
Autor:
Dennis L. Wright, Jieying Liu, Amy C. Anderson, David B. Bolstad, Kathleen M. Frey, Michael N. Lombardo
Publikováno v:
Journal of Molecular Biology. 387:1298-1308
Both hospital- and community-acquired Staphylococcus aureus infections have become major health concerns in terms of morbidity, suffering and cost. Trimethoprim-sulfamethoxazole (TMP-SMZ) is an alternative treatment for methicillin-resistant S. aureu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da9d485eb66ea81f0a8e36bb570da81
https://doi.org/10.1016/j.jmb.2009.02.045
https://doi.org/10.1016/j.jmb.2009.02.045
Autor:
Phillip M. Pelphrey, Adrienne E. Smith, Jennifer M. Beierlein, Dennis L. Wright, Nigel D. Priestley, Amy C. Anderson, Tammy M. Joska, David B. Bolstad, Kathleen M. Frey
Publikováno v:
Journal of Medicinal Chemistry. 51:7532-7540
Bacillus anthracis, the causative agent of anthrax, poses a significant biodefense danger. Serious limitations in approved therapeutics and the generation of resistance have produced a compelling need for new therapeutic agents against this organism.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da159c83adcec66728a7da4b32d640fc
https://doi.org/10.1021/jm800776a
https://doi.org/10.1021/jm800776a
Publikováno v:
Journal of Medicinal Chemistry. 51:6839-6852
Cryptosporidiosis is an emerging infectious disease that can be life-threatening in an immune-compromised individual and causes gastrointestinal distress lasting up to 2 weeks in an immune-competent individual. There are few therapeutics available fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::667da710aa28b5b8d1b7c22bd863c890
https://doi.org/10.1021/jm8009124
https://doi.org/10.1021/jm8009124
Publikováno v:
Expert Opinion on Therapeutic Patents. 18:143-157
Background: Infections caused by parasitic protozoa present a growing health concern, particularly in developing parts of the world. Although malaria is clearly the most well-known and deadly of these diseases, infections caused by other parasites, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d0fa2da4e80d4d105968276610a495
https://doi.org/10.1517/13543776.18.2.143
https://doi.org/10.1517/13543776.18.2.143
Publikováno v:
Synlett. 2007:2647-2650
In this letter, we describe the first approach to the synthesis of C8-oxygenated eunicellin diterpenes starting with a highly functionalized 8-oxabicyclo[3.2.1]octadiene system. The route features two sequential annulations to append a six- and five-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9af2176ce5042966586bb7d60c38d61
https://doi.org/10.1055/s-2007-986667
https://doi.org/10.1055/s-2007-986667
Publikováno v:
Global Change Biology. 11:435-449
The response of respiration to temperature in plants can be considered at both short- and long-term temporal scales. Short-term temperature responses are not well described by a constant Q10 of respiration, and longer-term responses often include acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9f61b51ad950c5c373475fb86a2816d
https://doi.org/10.1111/j.1365-2486.2005.00922.x
https://doi.org/10.1111/j.1365-2486.2005.00922.x
Publikováno v:
Acta Radiologica. 35:614-618
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28164e827a6b6f8966a62d145a00d36d
https://doi.org/10.3109/02841859409173332
https://doi.org/10.3109/02841859409173332
Publikováno v:
Acta Radiologica. 35:614-618
Iodixanol (Visipaque) 320 mg I/ml, a non-ionic, dimeric, isotonic contrast medium, was compared to ioxaglate (Hexabrix) 320 mg I/ml in cardioangiography. One hundred and two patients with normal renal function were included in the study. The objectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2702e749d99c9943a6700863216fddbe
https://doi.org/10.1080/02841859409173332
https://doi.org/10.1080/02841859409173332