Zobrazeno 1 - 10
of 1 023
pro vyhledávání: '"B, Bode"'
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background Bacteria of the genus Photorhabdus and Xenorhabdus are motile, Gram-negative bacteria that live in symbiosis with entomopathogenic nematodes. Due to their complex life cycle, they produce a large number of specialized metabolites
Externí odkaz:
https://doaj.org/article/921df6c5505048f3a4409dd601213ffa
Publikováno v:
Advanced Science, Vol 11, Iss 22, Pp n/a-n/a (2024)
Abstract Pigments such as anthraquinones (AQs) and melanins are antioxidants, protectants, or virulence factors. AQs from the entomopathogenic bacterium Photorhabdus laumondii are produced by a modular type II polyketide synthase system. A key enzyme
Externí odkaz:
https://doaj.org/article/cce2ca2818f644139bcc9617ab6661b7
Autor:
Amir Pandi, David Adam, Amir Zare, Van Tuan Trinh, Stefan L. Schaefer, Marie Burt, Björn Klabunde, Elizaveta Bobkova, Manish Kushwaha, Yeganeh Foroughijabbari, Peter Braun, Christoph Spahn, Christian Preußer, Elke Pogge von Strandmann, Helge B. Bode, Heiner von Buttlar, Wilhelm Bertrams, Anna Lena Jung, Frank Abendroth, Bernd Schmeck, Gerhard Hummer, Olalla Vázquez, Tobias J. Erb
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Bioactive peptides are key molecules in health and medicine. Deep learning holds a big promise for the discovery and design of bioactive peptides. Yet, suitable experimental approaches are required to validate candidates in high throughput a
Externí odkaz:
https://doaj.org/article/adbbacf7db9c45aca2f0981cf0f79344
Autor:
Wipanee Meesil, Paramaporn Muangpat, Sutthirat Sitthisak, Triwit Rattanarojpong, Narisara Chantratita, Ricardo A. R. Machado, Yi-Ming Shi, Helge B. Bode, Apichat Vitta, Aunchalee Thanwisai
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract The discovery of novel bioactive compounds produced by microorganisms holds significant potential for the development of therapeutics and agrochemicals. In this study, we conducted genome mining to explore the biosynthetic potential of entom
Externí odkaz:
https://doaj.org/article/625092019f564549a48e0f87876a4270
Autor:
Gahyeon Jin, Md Tafim Hossain Hrithik, Dong-Hee Lee, Il-Hwan Kim, Ji-Seon Jung, Helge B. Bode, Yonggyun Kim
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
An entomopathogenic bacterium, Photorhabdus temperata subsp. temperata, is mutualistic to its host nematode, Heterorhabditis megidis. The infective juvenile nematodes enter target insects through natural openings and release the symbiotic bacteria in
Externí odkaz:
https://doaj.org/article/2ddc154147b64141a8d464774f303b4c
Autor:
Leopoldo Palma, Laureano Frizzo, Sebastian Kaiser, Colin Berry, Primitivo Caballero, Helge B. Bode, Eleodoro Eduardo Del Valle
Publikováno v:
Toxins, Vol 16, Iss 2, p 108 (2024)
Entomopathogenic nematodes from the genus Steinernema (Nematoda: Steinernematidae) are capable of causing the rapid killing of insect hosts, facilitated by their association with symbiotic Gram-negative bacteria in the genus Xenorhabdus (Enterobacter
Externí odkaz:
https://doaj.org/article/6833fdd141d742daa58e801dd954c061
Autor:
Sebnem Hazal Gulsen, Evren Tileklioglu, Edna Bode, Harun Cimen, Hatice Ertabaklar, Derya Ulug, Sema Ertug, Sebastian L. Wenski, Mustapha Touray, Canan Hazir, Duygu Kaya Bilecenoglu, Ibrahim Yildiz, Helge B. Bode, Selcuk Hazir
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Natural products have been proven to be important starting points for the development of new drugs. Bacteria in the genera Photorhabdus and Xenorhabdus produce antimicrobial compounds as secondary metabolites to compete with other organisms.
Externí odkaz:
https://doaj.org/article/2834b885765c4fc79432f5af53f556d3
Autor:
Bahar Behsaz, Edna Bode, Alexey Gurevich, Yan-Ni Shi, Florian Grundmann, Deepa Acharya, Andrés Mauricio Caraballo-Rodríguez, Amina Bouslimani, Morgan Panitchpakdi, Annabell Linck, Changhui Guan, Julia Oh, Pieter C. Dorrestein, Helge B. Bode, Pavel A. Pevzner, Hosein Mohimani
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Current genome mining methods predict many putative non-ribosomal peptides (NRPs) from their corresponding biosynthetic gene clusters, but it remains unclear which of those exist in nature and how to identify their post-assembly modifications. Here,
Externí odkaz:
https://doaj.org/article/56701c0cd5c2408cb5012222fe11866d
Autor:
Gamze Incedayi, Harun Cimen, Derya Ulug, Mustapha Touray, Edna Bode, Helge B. Bode, Esra Orenlili Yaylagul, Selcuk Hazir, Ibrahim Cakmak
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Our study aimed to identify the novel acaricidal compound in Xenorhabdus szentirmaii and X. nematophila using the easyPACId approach (easy Promoter Activated Compound Identification). We determined the (1) effects of cell-free supernatant (C
Externí odkaz:
https://doaj.org/article/37ba05506e034345819bf327809ad534
Autor:
Sebastian L. Wenski, Harun Cimen, Natalie Berghaus, Sebastian W. Fuchs, Selcuk Hazir, Helge B. Bode
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 956-965 (2020)
The global threat of multiresistant pathogens has to be answered by the development of novel antibiotics. Established antibiotic applications are often based on so-called secondary or specialized metabolites (SMs), identified in large screening appro
Externí odkaz:
https://doaj.org/article/821e03fbf10b4688a31b44c77cfb83d9