Zobrazeno 1 - 10
of 100
pro vyhledávání: '"B, Bätge"'
Publikováno v:
DMW - Deutsche Medizinische Wochenschrift. 125:761-765
History An 82-year-old woman was admitted with bilateral clavicular fractures after falling out of bed. She complained of pain in all her bones. She reported having undergone a partial gastrectomy (Billroth II) 40 years ago with subsequent milk intol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5156ab24df9aa3c4beb72f8938027fb
https://doi.org/10.1055/s-2007-1024492
https://doi.org/10.1055/s-2007-1024492
Autor:
Rupert Timpl, Holger Notbohm, Kerstin Tiedemann, Erika Gustafsson, Ursula Schlötzer-Schrehardt, Dieter P. Reinhardt, Takako Sasaki, Thilo Wedel, B. Bätge, Walter Göhring
Publikováno v:
Journal of Biological Chemistry. 280:11404-11412
Mutational defects in fibrillin-rich microfibrils give rise to a number of heritable connective tissue disorders, generally termed microfibrillopathies. To understand the pathogenesis of these microfibrillopathies, it is important to elucidate the su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::370838d4adabbce4788e30e95884247c
https://doi.org/10.1074/jbc.m409882200
https://doi.org/10.1074/jbc.m409882200
Consequences of Cysteine Mutations in Calcium-binding Epidermal Growth Factor Modules of Fibrillin-1
Autor:
Guoqing Lin, B. Bätge, Harald John, Tillman Vollbrandt, Holger Notbohm, Ehab I. El-Hallous, Kerstin Tiedemann, Dieter P. Reinhardt, Jürgen Brinckmann
Publikováno v:
Journal of Biological Chemistry. 279:32924-32931
Mutations in fibrillin-1 lead to Marfan syndrome and some related genetic disorders. Many of the more than 600 mutations currently known in fibrillin-1 eliminate or introduce cysteine residues in epidermal growth factor-like modules. Here we report s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a22480fc75d91b298619d0b12f18440
https://doi.org/10.1074/jbc.m405239200
https://doi.org/10.1074/jbc.m405239200
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 108:311-315
The cell surface expression of receptors for TGF-beta was studied in human osteoblasts derived from femoral trabecular bone of a total of 19 patients aged 2-83 years. All cell populations investigated showed a similar profile of expression of TGF-bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb31e1dbdd6d3143cd58473081abc0d6
https://doi.org/10.1055/s-2000-8001
https://doi.org/10.1055/s-2000-8001
Autor:
Yahya Açil, Michael Tronnier, Holger Notbohm, Peter P. Fietzek, B. Bätge, W. Schmeller, Peter K. Müller, Jürgen Brinckmann
Publikováno v:
Journal of Investigative Dermatology. 113(4):617-621
In fibrotic skin of lipodermatosclerosis a substantial increase of the cross-link hydroxylysylpyridinoline is observed. Hydroxylysylpyridinoline is a typical cross-link of skeletal tissue and is thought to play a major part in the hardening of sclero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3954071759ee7cad76064ba20c5cb178
Publikováno v:
Journal of Endocrinology. 161:503-510
High concentrations of transforming growth factor b (TGF-beta) are found in the bone matrix, reflecting a pivotal role of this growth factor in the coupling of bone resorption and formation. TGF-beta strongly stimulates the synthesis of extracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9af70fa954e5f588ea065edf1fe9810
https://doi.org/10.1677/joe.0.1610503
https://doi.org/10.1677/joe.0.1610503
Publikováno v:
European Journal of Clinical Investigation. 25:959-966
Transforming growth factor beta 1 (TGF-beta 1) is an osteotropic growth factor that is found in substantial concentration in bone. The authors studied the influence of TGF-beta 1 on the modification of lysine residues of collagen I. The degree of lys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e2f623ef728f033314448ce197ce84
https://doi.org/10.1111/j.1365-2362.1995.tb01974.x
https://doi.org/10.1111/j.1365-2362.1995.tb01974.x
Autor:
A. Martinez, Jürgen Brinckmann, B. Bätge, C. Eisenbeiss, M. Hagedorn‐Greiwe, Dieter P. Reinhardt
Publikováno v:
British Journal of Dermatology. 149:850-852
Summary Background The diagnosis of Ehlers–Danlos syndrome (EDS) is mainly based on clinical criteria, although in some instances a sound molecular diagnosis is available. Clinical signs can be divided into two categories: one with high diagnostic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10d224dd1cc6cb2b046fdde961d62c4
https://doi.org/10.1046/j.1365-2133.2003.05439.x
https://doi.org/10.1046/j.1365-2133.2003.05439.x
Publikováno v:
RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren. 158:475-478
Bone density measurements were performed on 51 patients with suspected osteoporosis. We used DE-QCT and DEXA. The methods were compared with regard to deviation from normal. In 29 of the 51 patients there was more than half standard deviation and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::891b27a8fa4a4d3e7664153818741b9a
https://doi.org/10.1055/s-2008-1032685
https://doi.org/10.1055/s-2008-1032685
Publikováno v:
Journal of Protein Chemistry. 11:635-643
Pepsin-solubilized collagen I from skin and bone was analyzed with regard to its thermal stability as a triple helical molecule in solution and after in vitro fibril formation. Collagen I from human control bone was compared with samples showing defi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::717f274a90ab414f60cea7905eb0a03a
https://doi.org/10.1007/bf01024964
https://doi.org/10.1007/bf01024964