Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Azzedine Aouimer"'
Publikováno v:
Journal of biopharmaceutical statistics. 14(1)
The aim of this work is to quantitatively assess the impact of structural model misspecifications on the estimates of mean and interindividual variability of clearance in the context of population approaches. This assessment is conducted from simulat
Publikováno v:
Computer methods and programs in biomedicine. 67(1)
The contribution of non-linear orthogonal regression for estimation of individual pharmacokinetic parameters when drug concentrations and sampling times are subject to error was studied. The first objective was to introduce and compare four numerical