Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Azza B El-Remessy"'
Autor:
Azza B El-Remessy, Telina Franklin, Nagla Ghaley, Jinling Yang, Michael W Brands, Ruth B Caldwell, Mohamed Ali Behzadian
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186749 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0071868.].
Externí odkaz:
https://doaj.org/article/c65c39eac3c84b38be6db7c23c69cb0e
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 2, Iss , Pp - (2015)
Accumulation of the nerve growth factor precursor (proNGF) and its receptor p75NTR have been associated with several neurodegenerative diseases in both brain and retina. However, whether proNGF contributes to microvascular degeneration remain unexplo
Externí odkaz:
https://doaj.org/article/e24c2c97df4a432a993ffd2fda981ed8
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110388 (2014)
We have recently shown that thioredoxin interacting protein (TXNIP) is required for VEGF-mediated VEGFR2 receptor activation and angiogenic signal. Retinas from TXNIP knockout mice (TKO) exhibited higher cellular antioxidant defense compared to wild
Externí odkaz:
https://doaj.org/article/894f7bb96d484077bfa93112970416d2
Autor:
Azza B El-Remessy, Telina Franklin, Nagla Ghaley, Jinling Yang, Michael W Brands, Ruth B Caldwell, Mohamed Ali Behzadian
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71868 (2013)
Diabetes-induced breakdown of the blood-retinal barrier (BRB) has been linked to hyperglycemia-induced expression of vascular endothelial growth factor (VEGF) and is likely mediated by an increase in oxidative stress. We have shown that VEGF increase
Externí odkaz:
https://doaj.org/article/f3e142bd95164e89b39cbdb9ac1a3155
Autor:
Mohammed M H Al-Gayyar, Barbara A Mysona, Suraporn Matragoon, Mohammed A Abdelsaid, Mona F El-Azab, Ahmed Y Shanab, Yonju Ha, Sylvia B Smith, Kathryn E Bollinger, Azza B El-Remessy
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54692 (2013)
Our previous studies showed positive correlation between accumulation of proNGF, activation of RhoA and neuronal death in diabetic models. Here, we examined the neuroprotective effects of selective inhibition of RhoA kinase in the diabetic rat retina
Externí odkaz:
https://doaj.org/article/0c89936eb4594b909d45a4b4e0347303
Autor:
Weihua Guan, Payaningal R Somanath, Anna Kozak, Anna Goc, Azza B El-Remessy, Adviye Ergul, Maribeth H Johnson, Ahmed Alhusban, Sahar Soliman, Susan C Fagan
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24551 (2011)
We identified that the angiotensin receptor antagonist, candesartan, has profound neurovascular protective properties when administered after ischemic stroke and was associated with a proangiogenic state at least partly explained by vascular endothel
Externí odkaz:
https://doaj.org/article/da57f93dd8944e7fa2bf6f23546b2213
Autor:
Azza B. El-Remessy
Publikováno v:
Endocrines, Vol 3, Iss 4, Pp 801-812 (2022)
Diabetic ketoacidosis (DKA) is the most common hyperglycemic emergency and causes the greatest risk for death that could be prevented in patients with diabetes mellitus. DKA occurs more commonly among patients with type-1 diabetes with a thirty perce
Externí odkaz:
https://doaj.org/article/855bde81d83d4233b3a662aa036209ff
Autor:
Saifudeen Ismael, Sanaz Nasoohi, Lexiao Li, Khurram S. Aslam, Mohammad Moshahid Khan, Azza B. El-Remessy, Michael P. McDonald, Francesca-Fang Liao, Tauheed Ishrat
Publikováno v:
Neurobiology of Disease, Vol 156, Iss , Pp 105399- (2021)
Immune system hypersensitivity is believed to contribute to mental frailty in the elderly. Solid evidence indicates NOD-like receptor pyrin domain containing-3 (NLRP3)-inflammasome activation intimately connects aging-associated chronic inflammation
Externí odkaz:
https://doaj.org/article/62fc7f302ada4afc90c2d1aa3296b352
Autor:
Sally L. Elshaer, Hang-soo Park, Laura Pearson, William D. Hill, Frank M. Longo, Azza B. El-Remessy
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 829 (2021)
Mesenchymal stem cells (MSCs) are a promising therapy to improve vascular repair, yet their role in ischemic retinopathy is not fully understood. The aim of this study is to investigate the impact of modulating the neurotrophin receptor; p75NTR on th
Externí odkaz:
https://doaj.org/article/27858a60851d406db6aec05665ca76f8
Autor:
Sally L. Elshaer, Salma H. Bahram, Pranav Rajashekar, Rajashekhar Gangaraju, Azza B. El-Remessy
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 23, Iss 249, p 249 (2022)
International Journal of Molecular Sciences, Vol 23, Iss 249, p 249 (2022)
Mesenchymal stem cells are multipotent stem cells isolated from various tissue sources, including but not limited to bone marrow, adipose, umbilical cord, and Wharton Jelly. Although cell-mediated mechanisms have been reported, the therapeutic effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c36a7bdee93519e0993182a0e4f7c2e
https://pubmed.ncbi.nlm.nih.gov/35008675
https://pubmed.ncbi.nlm.nih.gov/35008675