Tracking the Antigenic Evolution of Foot-and-Mouth Disease Virus.

Autor: Richard Reeve, Daryl W Borley, Francois F Maree, Sasmita Upadhyaya, Azwidowi Lukhwareni, Jan J Esterhuysen, William T Harvey, Belinda Blignaut, Elizabeth E Fry, Satya Parida, David J Paton, Mana Mahapatra

Publikováno v: PLoS ONE, Vol 11, Iss 7, p e0159360 (2016)

Quantifying and predicting the antigenic characteristics of a virus is something of a holy grail for infectious disease research because of its central importance to the emergence of new strains, the severity of outbreaks, and vaccine selection. Howe

Externí odkaz: https://doaj.org/article/b9ad828d94c84c1a9ca4a2b4d1f096f1

Cytology compared with Hybrid Capture 2 human papilloma virus cervical cancer screening in HIV positive and HIV negative South African women

Autor: Leon Cornelius Snyman, Karin Louise Richter, Azwidowi Lukhwareni, Gerrit Dreyer, Matthys Hendrik Botha, F Haynes Van Der Merwe, Cathy Visser, Greta Dreyer

Publikováno v: International Journal of Gynecologic Cancer. 33:669-675

ObjectivesCervical cancer is preventable and caused by persistent infection with oncogenic human papilloma virus (HPV) types. HPV screening is more sensitive and is the preferred screening test. HPV screening data are mainly from developed settings,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ce68af2faa4c17026c768b731caa5ad5
https://doi.org/10.1136/ijgc-2022-003897

Post-treatment monitoring by ASCL1/LHX8 methylation analysis in women with HIV treated for cervical intraepithelial neoplasia grade 2/3

Autor: Frederique J. Vink, Renske D.M. Steenbergen, Wieke W. Kremer, Birgit I. Lissenberg-Witte, Daniëlle A.M. Heideman, Maaike C.G. Bleeker, Marjolein van Zummeren, Erika Breytenbach, Cathy Visser, Azwidowi Lukhwareni, Chris J.L.M. Meijer, Greta Dreyer

Publikováno v: AIDS (London, England), 36(7), 953-961. Lippincott Williams and Wilkins
Vink, F J, Steenbergen, R D M, Kremer, W W, Lissenberg-Witte, B I, Heideman, D A M, Bleeker, M C G, van Zummeren, M, Breytenbach, E, Visser, C, Lukhwareni, A, Meijer, C J L M & Dreyer, G 2022, ' Post-treatment monitoring by ASCL1/LHX8 methylation analysis in women with HIV treated for cervical intraepithelial neoplasia grade 2/3 ', AIDS (London, England), vol. 36, no. 7, pp. 953-961 . https://doi.org/10.1097/QAD.0000000000003197

Objective:Women with HIV (WWH) have an increased risk to develop recurrent cervical intraepithelial neoplasia grade 2/3 (rCIN2/3) after treatment compared with HIV-negative women. Therefore, appropriate posttreatment monitoring of WWH is important. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0057fcc248c3853650a2db213c8cb807
https://research.vumc.nl/en/publications/368d8035-bcf9-4d12-b4f7-b5fda9373928

Evidence of susceptibility to lamivudine-based HAART and genetic stability of hepatitis B virus (HBV) in HIV co-infected patients: A South African longitudinal HBV whole genome study

Autor: M. Jeffrey Mphahlele, J. Nare Rakgole, Edina Amponsah-Dacosta, Maemu P. Gededzha, Selokela G. Selabe, Jason T. Blackard, Azwidowi Lukhwareni

Publikováno v: Infection, Genetics and Evolution. 43:232-238

Background Reports on the concomitant impact of HIV co-infection and long term highly active anti-retroviral therapy (HAART) on the genetic stability and molecular evolution of HBV are limited in sub-Saharan Africa. Materials and methods This retrosp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a8a303973bab9fce8bb0767f971ff6
https://doi.org/10.1016/j.meegid.2016.05.035

High prevalence of the K65R mutation in HIV-1 subtype C infected patients failing tenofovir-based first-line regimens in South Africa

Autor: Sergio Carmona, Lindiwe Skhosana, Wendy S. Stevens, Kim Steegen, Michelle Bronze, Azwidowi Lukhwareni, Maria A. Papathanasopoulos, Esrom Letsoalo

Publikováno v: PLoS ONE, Vol 10, Iss 2, p e0118145 (2015)
PLoS ONE

Background Tenofovir (TDF) has replaced stavudine (d4T) as the preferred nucleoside reverse transcriptase inhibitor (NRTI) in first-line regimens in South Africa, but limited information is available on the resistance patterns that develop after the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8553492fc9d5ff0858cbc2af04c23eb6
http://europepmc.org/articles/PMC4320083?pdf=render