Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Azusa, Shibazaki"'
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Activation of NF-κB transcription factors is critical for innate immune cells to induce inflammation and fight against microbial pathogens. On the other hand, the excessive and prolonged activation of NF-κB causes massive inflammatory damage to the
Externí odkaz:
https://doaj.org/article/539891c83bb74a5babb081811dc287ef
Autor:
Jun'ichi Kobayashi, Takaaki Kubota, Yohei Takahashi, Naonobu Tanaka, Tohru Gonoi, Jane Fromont, Azusa Shibazaki, Haruaki Ishiyama
Publikováno v:
Tetrahedron. 68:8545-8550
The structures of seven new secondary metabolites isolated from an Okinawan marine sponge Suberites sp., nakijinamines A (1), B (2), and F–I (3–6) and 6-bromoconicamin (7), have been elucidated on the basis of spectroscopic analysis, chemical con
Autor:
Takashi Sato, Azusa Shibazaki, Hisashi Narimatsu, Toshihide Shikanai, Rikio Yabe, Tohru Gonoi, Hiroaki Tateno, Jun Hirabayashi
Publikováno v:
Glycobiology. 22:210-220
Human zymogen granule protein 16 (ZG16p) contains a Jacalin-like lectin domain, although its glycan-binding properties are not fully understood. Here, we screened the glycan-binding specificity of ZG16p by recently developed glycoconjugate microarray
Publikováno v:
Tetrahedron. 67:6689-6696
Five new isomalabaricane-type triterpenoids, stelliferins J–N (1–5), were isolated from Okinawan marine sponge Rhabdastrella cf. globostellata. The structures of 1–5 were elucidated from the spectroscopic data and chemical means including appli
Publikováno v:
Tetrahedron Letters. 52:3575-3578
Two new meroterpenoids, yojironins A (1) and B (2), were isolated from the whole plants of Hypericum yojiroanum, together with two new prenylated acylphloroglucinols, yojironins C (3) and D (4). Their structures were elucidated by spectroscopic data.
Autor:
Jane Fromont, Tohru Gonoi, Takaaki Kubota, Azusa Shibazaki, Yohei Takahashi, Jun'ichi Kobayashi
Publikováno v:
Organic Letters. 13:3016-3019
Three new heteroaromatic alkaloids, nakijinamines C-E (1-3), which are a hybrid of the aaptamine-type and bromoindole alkaloids possessing a taurine- or histidine-derived residue, have been isolated from an Okinawan marine sponge Suberites species. T
Publikováno v:
Journal of Carbohydrate Chemistry. 30:147-164
Fungal surface glycans play roles in cell protection and interaction. Our knowledge of fungal glycans, however, is limited to model yeasts and a few medically/industrially important fungi. We evaluated the usefulness of a lectin microarray in analysi
Autor:
Yoshihisa Takaishi, Naonobu Tanaka, Tohru Gonoi, Motoo Shiro, Mio Otani, Azusa Shibazaki, Jun'ichi Kobayashi, Yoshiki Kashiwada
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:4451-4455
Four new prenylated acylphloroglucinols, petiolins J-M (1-4), were isolated from aerial parts of Hypericum pseudopetiolatum var. kiusianum, and the structures were elucidated by spectroscopic data and a single-crystal X-ray diffraction analysis. Peti
HSP70 mediates degradation of the p65 subunit of nuclear factor κB to inhibit inflammatory signaling
Publikováno v:
Science signaling. 7(356)
The nuclear PDZ-LIM domain protein PDLIM2 acts as a ubiquitin E3 ligase that targets the p65 subunit of the transcription factor nuclear factor κB (NF-κB) for degradation, thus preventing excessive inflammatory responses. We found that the chaperon
Autor:
Azusa, Shibazaki, Tohru, Gonoi
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1200
Lectin microarrays are rows of lectins with different carbohydrate-binding specificities spotted on surfaces of glass slides. Lectin microarray technique enables glycomic analyses of carbohydrate composition of fungal cell walls. We will describe an