Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Azucena Salas"'
Autor:
Laura Jiménez-Gracia, Domenica Marchese, Juan C. Nieto, Ginevra Caratù, Elisa Melón-Ardanaz, Victoria Gudiño, Sara Roth, Kellie Wise, Natalie K. Ryan, Kirk B. Jensen, Xavier Hernando-Momblona, Joana P. Bernardes, Florian Tran, Laura Katharina Sievers, Stefan Schreiber, Maarten van den Berge, Tessa Kole, Petra L. van der Velde, Martijn C. Nawijn, Philip Rosenstiel, Eduard Batlle, Lisa M. Butler, Ian A. Parish, Jasmine Plummer, Ivo Gut, Azucena Salas, Holger Heyn, Luciano G. Martelotto
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-36 (2024)
Abstract The use of single-cell technologies for clinical applications requires disconnecting sampling from downstream processing steps. Early sample preservation can further increase robustness and reproducibility by avoiding artifacts introduced du
Externí odkaz:
https://doaj.org/article/d1ab6d70f44f4bfd844fa1f4befa4917
Autor:
Alba Garrido-Trigo, Ana M. Corraliza, Marisol Veny, Isabella Dotti, Elisa Melón-Ardanaz, Aina Rill, Helena L. Crowell, Ángel Corbí, Victoria Gudiño, Miriam Esteller, Iris Álvarez-Teubel, Daniel Aguilar, M. Carme Masamunt, Emily Killingbeck, Youngmi Kim, Michael Leon, Sudha Visvanathan, Domenica Marchese, Ginevra Caratù, Albert Martin-Cardona, Maria Esteve, Ingrid Ordás, Julian Panés, Elena Ricart, Elisabetta Mereu, Holger Heyn, Azucena Salas
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Ulcerative colitis and Crohn’s disease are chronic inflammatory intestinal diseases with perplexing heterogeneity in disease manifestation and response to treatment. While the molecular basis for this heterogeneity remains uncharacterized,
Externí odkaz:
https://doaj.org/article/91914e5f5fdd496f894dce921d226bce
Autor:
Amira Metwaly, Jelena Jovic, Nadine Waldschmitt, Sevana Khaloian, Helena Heimes, Deborah Häcker, Mohamed Ahmed, Nassim Hammoudi, Lionel Le Bourhis, Aida Mayorgas, Kolja Siebert, Marijana Basic, Tobias Schwerd, Matthieu Allez, Julian Panes, Azucena Salas, André Bleich, Sebastian Zeissig, Pamela Schnupf, Fabio Cominelli, Dirk Haller
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-21 (2023)
Abstract Background Crohn’s disease (CD) is associated with changes in the microbiota, and murine models of CD-like ileo-colonic inflammation depend on the presence of microbial triggers. Increased abundance of unknown Clostridiales and the microsc
Externí odkaz:
https://doaj.org/article/160bf4e0935a4c559e27d044a98b7180
Autor:
Beatriz Martín-Adrados, Stefanie K. Wculek, Sergio Fernández-Bravo, Raúl Torres-Ruiz, Ana Valle-Noguera, Maria José Gomez-Sánchez, José Carlos Hernández-Walias, Frederico Moraes Ferreira, Ana María Corraliza, David Sancho, Vanesa Esteban, Sandra Rodriguez-Perales, Aránzazu Cruz-Adalia, Helder I. Nakaya, Azucena Salas, David Bernardo, Yolanda Campos-Martín, Elena Martínez-Zamorano, Diego Muñoz-López, Manuel Gómez del Moral, Francisco Javier Cubero, Richard S. Blumberg, Eduardo Martínez-Naves
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe Unfolded Protein Response, a mechanism triggered by the cell in response to Endoplasmic reticulum stress, is linked to inflammatory responses. Our aim was to identify novel Unfolded Protein Response-mechanisms that might be involved i
Externí odkaz:
https://doaj.org/article/59dfd819e60246a9be340bee3f602a6e
Autor:
Alba Garrido-Trigo, Ana M. Corraliza, Marisol Veny, Isabella Dotti, Elisa Melón-Ardanaz, Aina Rill, Helena L. Crowell, Ángel Corbí, Victoria Gudiño, Miriam Esteller, Iris Álvarez-Teubel, Daniel Aguilar, M. Carme Masamunt, Emily Killingbeck, Youngmi Kim, Michael Leon, Sudha Visvanathan, Domenica Marchese, Ginevra Caratù, Albert Martin-Cardona, Maria Esteve, Ingrid Ordás, Julian Panés, Elena Ricart, Elisabetta Mereu, Holger Heyn, Azucena Salas
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/b3bab41a702941269b02108c15092e84
Autor:
Laia Bonjoch, Yasmin Soares de Lima, Marcos Díaz-Gay, Isabella Dotti, Jenifer Muñoz, Leticia Moreira, Sabela Carballal, Teresa Ocaña, Miriam Cuatrecasas, Oswaldo Ortiz, Antoni Castells, Maria Pellisé, Francesc Balaguer, Azucena Salas, Ludmil B. Alexandrov, Sergi Castellví-Bel
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Serrated polyposis syndrome (SPS) is one of the most frequent polyposis syndromes characterized by an increased risk for developing colorectal cancer (CRC). Although SPS etiology has been mainly associated with environmental factors, germline predisp
Externí odkaz:
https://doaj.org/article/349b636d6eec4d70b45a16c39bd321da
Autor:
Bryan Linggi, Vipul Jairath, Guangyong Zou, Lisa M. Shackelton, Dermot P. B. McGovern, Azucena Salas, Bram Verstockt, Mark S. Silverberg, Shadi Nayeri, Brian G. Feagan, Niels Vande Casteele
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Publicly available ulcerative colitis (UC) gene expression datasets from observational studies and clinical trials include inherently heterogeneous disease characteristics and methodology. We used meta-analysis to identify a robust UC gene s
Externí odkaz:
https://doaj.org/article/7837a75292a542ebb02f0ecb74810914
Autor:
Sergi Casadó-Llombart, María Velasco-de Andrés, Cristina Català, Alejandra Leyton-Pereira, Rebeca Gutiérrez-Cózar, Belén Suárez, Noelia Armiger, Esther Carreras, Miriam Esteller, Elena Ricart, Ingrid Ordás, Javier P. Gisbert, María Chaparro, María Esteve, Lucía Márquez, David Busquets, Eva Iglesias, Esther García-Planella, María Dolores Martín-Arranz, Juliane Lohmann, C. Korcan Ayata, Jan Hendrik Niess, Pablo Engel, Julián Panés, Azucena Salas, Eugeni Domènech, Francisco Lozano, ENEIDA Project of GETECCU, Alfredo J. Lucendo, Jordi Guardiola, Xavier Calvet, Lorenzo Olivá́n, Marta Piqueras
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Crohn’s disease (CD) and ulcerative colitis (UC) are inflammatory bowel diseases (IBD) resulting from the interaction of multiple environmental, genetic and immunological factors. CD5 and CD6 are paralogs encoding lymphocyte co-receptors involved i
Externí odkaz:
https://doaj.org/article/f8c831491e61476d9916ae833d60eb38
Autor:
Amira Metwaly, Andreas Dunkel, Nadine Waldschmitt, Abilash Chakravarthy Durai Raj, Ilias Lagkouvardos, Ana Maria Corraliza, Aida Mayorgas, Margarita Martinez-Medina, Sinah Reiter, Michael Schloter, Thomas Hofmann, Matthieu Allez, Julian Panes, Azucena Salas, Dirk Haller
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Gut microbial and metabolite alterations are linked to inflammatory bowel diseases pathogenesis. Here the authors identify functional microbiota signatures that correlate with disease activity by comparing patients with Crohn’s disease undergoing a
Externí odkaz:
https://doaj.org/article/80a8a0456f1b494a8e06f154f92dc470
Autor:
Francesca Aparecida Ramos da Silva, Lívia Bitencourt Pascoal, Isabella Dotti, Maria de Lourdes Setsuko Ayrizono, Daniel Aguilar, Bruno Lima Rodrigues, Montserrat Arroyes, Elena Ferrer-Picon, Marciane Milanski, Lício Augusto Velloso, João José Fagundes, Azucena Salas, Raquel Franco Leal
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background Crohn’s disease (CD) is a multifactorial disease characterized by chronic intestinal inflammation. The increased visceral adiposity near the affected intestinal area, of which mesenteric adipose tissue (MAT) is the main componen
Externí odkaz:
https://doaj.org/article/4f48f6094b7a47ea9d311517c94e4c76