Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Azucena Lemus"'
Autor:
Misol Ahn, Krystyna Bajsarowicz, Abby Oehler, Azucena Lemus, Krystof Bankiewicz, Stephen J DeArmond
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98496 (2014)
Prion disease is caused by a single pathogenic protein (PrPSc), an abnormal conformer of the normal cellular prion protein PrPC. Depletion of PrPC in prion knockout mice makes them resistant to prion disease. Thus, gene silencing of the Prnp gene is
Externí odkaz:
https://doaj.org/article/66afdabe53f04fc4be59002124875636
Autor:
David W Colby, Rachel Wain, Ilia V Baskakov, Giuseppe Legname, Christina G Palmer, Hoang-Oanh B Nguyen, Azucena Lemus, Fred E Cohen, Stephen J DeArmond, Stanley B Prusiner
Publikováno v:
PLoS Pathogens, Vol 6, Iss 1, p e1000736 (2010)
Prions arise when the cellular prion protein (PrP(C)) undergoes a self-propagating conformational change; the resulting infectious conformer is designated PrP(Sc). Frequently, PrP(Sc) is protease-resistant but protease-sensitive (s) prions have been
Externí odkaz:
https://doaj.org/article/05d2fdbcce8f465787a434786e853dd7
Autor:
Giuseppe Legname, Stephen J. DeArmond, Holger Wille, Hoang-Oanh B. Nguyen, Joel C. Watts, Azucena Lemus, Joshua Sussman, Kurt Giles, Jan Stöhr, Abby Oehler, Stanley B. Prusiner
Publikováno v:
Proceedings of the National Academy of Sciences. 108:21223-21228
Some prion protein mutations create anchorless molecules that cause Gerstmann–Sträussler–Scheinker (GSS) disease. To model GSS, we generated transgenic mice expressing cellular prion protein (PrP C ) lacking the glycosylphosphatidyl inositol (GP
Autor:
Azucena Lemus, Stephen J. DeArmond, Jiri G. Safar, Robert Hnasko, Stanley B. Prusiner, Ana Serban, Larry H. Stanker, Elisa Cleveland
Publikováno v:
The Journal of Immunology. 185:729-737
Prion diseases are fatal, neurodegenerative illnesses caused by the accumulation of PrPSc, an aberrantly folded isoform of the normal, cellular prion protein. Detection of PrPSc commonly relies on immunochemical methods, a strategy hampered by the la
Autor:
Gültekin Tamgüney, Stephen J. DeArmond, Kurt Giles, Stanley B. Prusiner, Azucena Lemus, Kevin Francis
Publikováno v:
Proceedings of the National Academy of Sciences. 106:15002-15006
Prions are infectious proteins that cause fatal neurodegenerative diseases. Because astrocytic gliosis marked by the deposition of fibrils composed of GFAP is a prominent feature of prion disease, we asked whether GFAP might be used as a surrogate ma
Autor:
Tracey M. Sirochman, Azucena Lemus, Lisa L. Wolfe, David V. Glidden, Christina G.S. Palmer, Stanley B. Prusiner, Michael W. Miller, Gültekin Tamgüney, Stephen J. DeArmond
Publikováno v:
Nature
Nature, vol 461, iss 7263
Tamgüney, G; Miller, MW; Wolfe, LL; Sirochman, TM; Glidden, DV; Palmer, C; et al.(2009). Asymptomatic deer excrete infectious prions in faeces. Nature, 461(7263), 529-532. doi: 10.1038/nature08289. UCSF: Retrieved from: http://www.escholarship.org/uc/item/1jz6m94h
Nature, vol 461, iss 7263
Tamgüney, G; Miller, MW; Wolfe, LL; Sirochman, TM; Glidden, DV; Palmer, C; et al.(2009). Asymptomatic deer excrete infectious prions in faeces. Nature, 461(7263), 529-532. doi: 10.1038/nature08289. UCSF: Retrieved from: http://www.escholarship.org/uc/item/1jz6m94h
Infectious prion diseasesĝ€"scrapie of sheep and chronic wasting disease (CWD) of several species in the deer familyĝ€" are transmitted naturally within affected host populations. Although several possible sources of contagion have been identif
Publikováno v:
Universidad Michoacana de San Nicolás de Hidalgo
UMSNH
Repositorio Institucional de la Universidad Michoacana de San Nicolás de Hidalgo
UMSNH
Repositorio Institucional de la Universidad Michoacana de San Nicolás de Hidalgo
Facultad de Derecho y Ciencias Sociales. Maestría en Derecho de la Información The research presented is a study on the narcocorrido a focus of information law. Freedom of expression is a fundamental right, however, is not unfettered. One limitatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3056::d17a4d340aa8a029931a1d4278ef3766
http://bibliotecavirtual.dgb.umich.mx:8083/xmlui/handle/DGB_UMICH/600
http://bibliotecavirtual.dgb.umich.mx:8083/xmlui/handle/DGB_UMICH/600
Autor:
Krystyna Bajsarowicz, Azucena Lemus, Misol Ahn, Abby Oehler, Krystof S. Bankiewicz, Stephen J. DeArmond
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 5, p e98496 (2014)
Bankiewicz, Krzysztof; Ahn, M; Bajsarowicz, K; Oehler, A; Lemus, A; & DeArmond, SJ. (2014). Convection-enhanced delivery of AAV2-PrPshRNA in prion-infected mice.. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/6tz843jn
PLoS ONE, Vol 9, Iss 5, p e98496 (2014)
Bankiewicz, Krzysztof; Ahn, M; Bajsarowicz, K; Oehler, A; Lemus, A; & DeArmond, SJ. (2014). Convection-enhanced delivery of AAV2-PrPshRNA in prion-infected mice.. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/6tz843jn
Prion disease is caused by a single pathogenic protein (PrPSc), an abnormal conformer of the normal cellular prion protein PrPC. Depletion of PrPC in prion knockout mice makes them resistant to prion disease. Thus, gene silencing of the Prnp gene is
Autor:
Stanley B. Prusiner, Kurt Giles, Sunny K. Grillo, Azucena Lemus, Joel C. Watts, Stephen J. DeArmond
Transgenic (Tg) mouse models of Alzheimer's disease have served as valuable tools for investigating pathogenic mechanisms related to Aβ accumulation. However, assessing disease status in these animals has required time-consuming behavioral assessmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50fb69902b1ee59f67953e3ef95663e6
https://europepmc.org/articles/PMC3038719/
https://europepmc.org/articles/PMC3038719/
Autor:
Stephen J. DeArmond, Carsten Korth, Stanley B. Prusiner, Kurt Giles, Azucena Lemus, David V. Glidden, Darlene Groth, Smita S. Patel
Objective: Transgenic (Tg) mice expressing chimeras of mouse and human prion proteins (PrPs) have shorter incubation periods for Creutzfeldt-Jakob disease (CJD) prions than mice expressing full-length human PrP. Increasing the sequence similarity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d60994c10e5859692d2de5337d0eea5
https://europepmc.org/articles/PMC2935907/
https://europepmc.org/articles/PMC2935907/