Výsledky vyhledávání - "Azucena González-Navarro"

Akademický článek

NSGS mice humanized with cord blood mononuclear cells show sustained and functional myeloid–lymphoid representation with limited graft-versus-host disease

Autor: Jorge Carrillo, Julià Blanco, Manel Juan, Pablo Menendez, Rosario Aschero, Alba Martínez-Moreno, Carla Panisello, Heleia Roca Ho, Aida Falgas, Europa Azucena González-Navarro, Julieta Carabelli, Edwards Pradenas, María Lázaro-Díez, Julia G Prado, Ángel M Carcaboso, Clara Bueno

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 10 (2024)

Humanized immunodeficient mice serve as critical models for investigating the functional interplay between transplanted human cells and a pre-reconstituted human immune system. These models facilitate the study of molecular and cellular pathogenic me

Externí odkaz: https://doaj.org/article/bed49f3854d84262911d96cc974169ac

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Akademický článek

Cellular and humoral responses after second and third SARS-CoV-2 vaccinations in patients with autoimmune diseases treated with rituximab: specific T cell immunity remains longer and plays a protective role against SARS-CoV-2 reinfections

Autor: Natalia Egri, Hugo Calderón, Robert Martinez, Mario Vazquez, Verónica Gómez-Caverzaschi, Mariona Pascal, Olga Araújo, Manel Juan, Europa Azucena González-Navarro, José Hernández-Rodríguez

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

BackgroundHumoral and cellular immune responses are known to be crucial for patients to recover from COVID-19 and to protect them against SARS-CoV-2 reinfection once infected or vaccinated.ObjectivesThis study aimed to investigate humoral and T cell

Externí odkaz: https://doaj.org/article/fba262c9ad9740ea9f5441e5d4ea4dfc

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Akademický článek

Acute and long-term immune responses to SARS-CoV-2 infection in unvaccinated children and young adults with inborn errors of immunity

Autor: Ana García-García, Claudia Fortuny, Victoria Fumadó, Iolanda Jordan, Laura Ruiz-López, Europa Azucena González-Navarro, Natalia Egri, Ana Esteve-Solé, Yiyi Luo, Alexandru Vlagea, Manel Monsonís Cabedo, Cristian Launes, Aleix Soler, Anna Codina, Manel Juan, Mariona Pascal, Angela Deyà-Martínez, Laia Alsina

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

PurposeTo describe SARS-CoV-2 infection outcome in unvaccinated children and young adults with inborn errors of immunity (IEI) and to compare their specific acute and long-term immune responses with a sex-, age-, and severity-matched healthy populati

Externí odkaz: https://doaj.org/article/89571c6eaf904d93b09b9c7326300166

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Akademický článek

CoVITEST: A Fast and Reliable Method to Monitor Anti-SARS-CoV-2 Specific T Cells From Whole Blood

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Cellular and humoral immune responses are essential for COVID-19 recovery and protection against SARS-CoV-2 reinfection. To date, the evaluation of SARS-CoV-2 immune protection has mainly focused on antibody detection, generally disregarding the cell

Externí odkaz: https://doaj.org/article/e812613cd0b24345b15370c06f4a4ac4

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Akademický článek

Development of a Novel Anti-CD19 Chimeric Antigen Receptor: A Paradigm for an Affordable CAR T Cell Production at Academic Institutions

Publikováno v: Molecular Therapy: Methods & Clinical Development, Vol 12, Iss , Pp 134-144 (2019)

Genetically modifying autologous T cells to express an anti-CD19 chimeric antigen receptor (CAR) has shown impressive response rates for the treatment of CD19+ B cell malignancies in several clinical trials (CTs). Making this treatment available to o

Externí odkaz: https://doaj.org/article/0991d78034c649d5800886f6bf312afe

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Akademický článek

Point-Of-Care CAR T-Cell Production (ARI-0001) Using a Closed Semi-automatic Bioreactor: Experience From an Academic Phase I Clinical Trial

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

Development of semi-automated devices that can reduce the hands-on time and standardize the production of clinical-grade CAR T-cells, such as CliniMACS Prodigy from Miltenyi, is key to facilitate the development of CAR T-cell therapies, especially in

Externí odkaz: https://doaj.org/article/c4affb1899c8444da99e673d6cca6b80

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Akademický článek

Inflammatory dysregulation of monocytes in pediatric patients with obsessive-compulsive disorder

Autor: Natalia Rodríguez, Astrid Morer, E. Azucena González-Navarro, Carles Serra-Pages, Daniel Boloc, Teresa Torres, Susana García-Cerro, Sergi Mas, Patricia Gassó, Luisa Lázaro

Publikováno v: Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-11 (2017)

Abstract Background Although the exact etiology of obsessive-compulsive disorder (OCD) is unknown, there is growing evidence of a role for immune dysregulation in the pathophysiology of the disease, especially in the innate immune system including th

Externí odkaz: https://doaj.org/article/287672949fd54632a8e669b92b23f988

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Akademický článek

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