Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Azra Frkatović"'
Autor:
Panayiotis Louca, Tamara Štambuk, Azra Frkatović-Hodžić, Ana Nogal, Massimo Mangino, Sarah E. Berry, Helena Deriš, George Hadjigeorgiou, Jonathan Wolf, Martina Vinicki, Paul W. Franks, Ana M. Valdes, Tim D. Spector, Gordan Lauc, Cristina Menni
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background A dysregulated postprandial metabolic response is a risk factor for chronic diseases, including type 2 diabetes mellitus (T2DM). The plasma protein N-glycome is implicated in both lipid metabolism and T2DM risk. Hence, we first in
Externí odkaz:
https://doaj.org/article/14876c1e22a74b02acad0eb3e4d62e9c
Autor:
Aoife Murray, Gillian Gough, Ana Cindrić, Frano Vučković, David Koschut, Vincenzo Borelli, Dražen J. Petrović, Ana Bekavac, Ante Plećaš, Valentina Hribljan, Reinhard Brunmeir, Julija Jurić, Maja Pučić-Baković, Anita Slana, Helena Deriš, Azra Frkatović, Jűrgen Groet, Niamh L. O’Brien, Hong Yu Chen, Yee Jie Yeap, Frederic Delom, Steven Havlicek, Luke Gammon, Sarah Hamburg, Carla Startin, Hana D’Souza, Dinko Mitrečić, Mijana Kero, Ljubica Odak, Božo Krušlin, Željka Krsnik, Ivica Kostović, Jia Nee Foo, Yuin-Han Loh, Norris Ray Dunn, Susana de la Luna, Tim Spector, Ingeborg Barišić, Michael S.C. Thomas, Andre Strydom, Claudio Franceschi, Gordan Lauc, Jasminka Krištić, Ivan Alić, Dean Nižetić
Publikováno v:
EBioMedicine, Vol 94, Iss , Pp 104692- (2023)
Summary: Background: People with Down syndrome (DS) show clinical signs of accelerated ageing. Causative mechanisms remain unknown and hypotheses range from the (essentially untreatable) amplified-chromosomal-instability explanation, to potential act
Externí odkaz:
https://doaj.org/article/fccbd6f8ccf04865a74224623e30be79
Autor:
Anika Mijakovac, Azra Frkatović, Maja Hanić, Jelena Ivok, Marina Martinić Kavur, Maja Pučić-Baković, Tim Spector, Vlatka Zoldoš, Massimo Mangino, Gordan Lauc
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Immunoglobulin G is posttranslationally modified by the addition of complex N-glycans affecting its function and mediating inflammation at multiple levels. IgG glycome composition changes with age and health in a predictive pattern, presumably due to
Externí odkaz:
https://doaj.org/article/2143403fbdb3443e815d3b9629b792b8
Autor:
Nina Šimunić-Briški, Robert Zekić, Vedran Dukarić, Mateja Očić, Azra Frkatović-Hodžić, Helena Deriš, Gordan Lauc, Damir Knjaz
Publikováno v:
Biomolecules, Vol 13, Iss 5, p 762 (2023)
Regular exercise improves health, modulating the immune system and impacting inflammatory status. Immunoglobulin G (IgG) N-glycosylation reflects changes in inflammatory status; thus, we investigated the impact of regular exercise on overall inflamma
Externí odkaz:
https://doaj.org/article/efebfdc5a3d04e2bb06201039f4e1d3c
Autor:
Yanni Zeng, Carmen Amador, Chenhao Gao, Rosie M. Walker, Stewart W. Morris, Archie Campbell, Azra Frkatović, Rebecca A Madden, Mark J. Adams, Shuai He, Andrew D. Bretherick, Caroline Hayward, David J. Porteous, James F. Wilson, Kathryn L. Evans, Andrew M. McIntosh, Pau Navarro, Chris S. Haley
Publikováno v:
EBioMedicine, Vol 74, Iss , Pp 103730- (2021)
Background: parent-of-origin effects (POE) play important roles in complex disease and thus understanding their regulation and associated molecular and phenotypic variation are warranted. Previous studies mainly focused on the detection of genomic re
Externí odkaz:
https://doaj.org/article/074223ccfeb54427999eb66fd69ca4a5
Autor:
Anika Mijakovac, Julija Jurić, Wendy M. Kohrt, Jasminka Krištić, Domagoj Kifer, Kathleen M. Gavin, Karlo Miškec, Azra Frkatović, Frano Vučković, Marija Pezer, Aleksandar Vojta, Peter A. Nigrović, Vlatka Zoldoš, Gordan Lauc
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Glycans attached to immunoglobulin G (IgG) directly affect this antibody effector functions and regulate inflammation at several levels. The composition of IgG glycome changes significantly with age. In women, the most notable change coincides with t
Externí odkaz:
https://doaj.org/article/ce88315acded499881c6c9567bc6cb59
Autor:
Laxmi Sunuwar, Azra Frkatović, Sodbo Sharapov, Qinchuan Wang, Heather M. Neu, Xinqun Wu, Talin Haritunians, Fengyi Wan, Sarah Michel, Shaoguang Wu, Mark Donowitz, Dermot McGovern, Gordan Lauc, Cynthia Sears, Joanna Melia
Publikováno v:
JCI Insight, Vol 5, Iss 20 (2020)
ZIP8 is a metal transporter with a role in manganese (Mn) homeostasis. A common genetic variant in ZIP8 (rs13107325; A391T) ranks in the top 10 of pleiotropic SNPs identified in GWAS; A391T has associations with an increased risk of schizophrenia, ob
Externí odkaz:
https://doaj.org/article/c8a8d7250ef44726afdebb8c100fb512
Autor:
Azra Frkatović-Hodžić, Karlo Miškec, Anika Mijakovac, Arina Nostaeva, Sodbo Z. Sharapov, Arianna Landini, Toomas Haller, Erik van den Akker, Sapna Sharma, Rafael R. C. Cuadrat, Massimo Mangino, Yong Li, Toma Keser, Najda Rudman, Tamara Štambuk, Maja Pučić-Baković, Irena Trbojević-Akmačić, Ivan Gudelj, Jerko Štambuk, Tea Pribić, Barbara Radovani, Petra Tominac, Krista Fischer, Marian Beekman, Manfred Wuhrer, Christian Gieger, Matthias B. Schulze, Clemens Wittenbecher, Ozren Polasek, Caroline Hayward, James F. Wilson, Tim D. Spector, Anna Köttgen, Frano Vučković, Yurii S. Aulchenko, Aleksandar Vojta, Jasminka Krištić, Lucija Klarić, Vlatka Zoldoš, Gordan Lauc
Glycans are an essential structural component of Immunoglobulin G (IgG) that modulate its structure and function. However, regulatory mechanisms behind this complex posttranslational modification are not well known. Previous genome-wide association s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d92d3302502fc9912a10a4d1815f33e6
https://doi.org/10.1101/2023.04.25.23289027
https://doi.org/10.1101/2023.04.25.23289027
Autor:
Ana Cindric, Frano Vuckovic, David Koschut, Vincenzo Borelli, Julija Juric, Maja Pucic-Bakovic, Anita Slana, Helena Deris, Azra Frkatović, Aoife Murray, Ivan Alic, Jurgen Groet, Niamh O’Brien, Drazen Petrovic, Sarah Hamburg, Carla Startin, Rosalyn Hithersay, Hana D’Souza, LonDownS Consortium, Tim Spector, Dinko Mitrecic, Mijana Kero, Ljubica Odak, Ingeborg Barisic, Michael Thomas, Andre Strydom, Anne-Sophie Rebillat, Claudio Franceschi, Gordan Lauc, Jasminka Kristic, Dean Nizetic
Cells from people with Down syndrome (DS) show faster accumulation of DNA damage and epigenetic aging marks. Causative mechanisms remain un-proven and hypotheses range from amplified chromosomal instability to actions of several supernumerary chromos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::548515c2398e5b88c12e6b8f505b6b96
https://doi.org/10.21203/rs.3.rs-1128079/v1
https://doi.org/10.21203/rs.3.rs-1128079/v1
Glycosylation of immunoglobulin G (IgG) largely defines function of this antibody and regulates inflammation on multiple levels but the mechanisms and the genes involved in the process of IgG glycosylation are still vaguely understood. Genome wide as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::177d08a6dfd4b83b99821367903e5c1a
https://www.bib.irb.hr/1161656
https://www.bib.irb.hr/1161656