Zobrazeno 1 - 10
of 320
pro vyhledávání: '"Azra C Ghani"'
Autor:
Nora Schmit, Hillary M Topazian, Matteo Pianella, Giovanni D Charles, Peter Winskill, Michael T White, Katharina Hauck, Azra C Ghani
Publikováno v:
eLife, Vol 12 (2024)
Large reductions in the global malaria burden have been achieved, but plateauing funding poses a challenge for progressing towards the ultimate goal of malaria eradication. Using previously published mathematical models of Plasmodium falciparum and P
Externí odkaz:
https://doaj.org/article/7678cace3246411986135e01cb8280c6
Autor:
Alexandra B Hogan, Sean L Wu, Jaspreet Toor, Daniela Olivera Mesa, Patrick Doohan, Oliver J Watson, Peter Winskill, Giovanni Charles, Gregory Barnsley, Eleanor M Riley, David S Khoury, Neil M Ferguson, Azra C Ghani
Publikováno v:
PLoS Medicine, Vol 20, Iss 11, p e1004195 (2023)
BackgroundVaccines have reduced severe disease and death from Coronavirus Disease 2019 (COVID-19). However, with evidence of waning efficacy coupled with continued evolution of the virus, health programmes need to evaluate the requirement for regular
Externí odkaz:
https://doaj.org/article/24be92e134bd43bc963c1648797ccc41
Publikováno v:
PLoS Medicine, Vol 17, Iss 11, p e1003377 (2020)
BackgroundThe RTS,S/AS01 vaccine against Plasmodium falciparum malaria infection completed phase III trials in 2014 and demonstrated efficacy against clinical malaria of approximately 36% over 4 years for a 4-dose schedule in children aged 5-17 month
Externí odkaz:
https://doaj.org/article/1eb31262413e423a81b833f2bd42bd6b
Autor:
Andria Mousa, Abdullah Al-Taiar, Nicholas M Anstey, Cyril Badaut, Bridget E Barber, Quique Bassat, Joseph D Challenger, Aubrey J Cunnington, Dibyadyuti Datta, Chris Drakeley, Azra C Ghani, Victor R Gordeuk, Matthew J Grigg, Pierre Hugo, Chandy C John, Alfredo Mayor, Florence Migot-Nabias, Robert O Opoka, Geoffrey Pasvol, Claire Rees, Hugh Reyburn, Eleanor M Riley, Binal N Shah, Antonio Sitoe, Colin J Sutherland, Philip E Thuma, Stefan A Unger, Firmine Viwami, Michael Walther, Christopher J M Whitty, Timothy William, Lucy C Okell
Publikováno v:
PLoS Medicine, Vol 17, Iss 10, p e1003359 (2020)
BackgroundDelay in receiving treatment for uncomplicated malaria (UM) is often reported to increase the risk of developing severe malaria (SM), but access to treatment remains low in most high-burden areas. Understanding the contribution of treatment
Externí odkaz:
https://doaj.org/article/ba8efe1bc73045abb15eedf4a63503a8
Autor:
Kylie E. C. Ainslie, Caroline E. Walters, Han Fu, Sangeeta Bhatia, Haowei Wang, Xiaoyue Xi, Marc Baguelin, Samir Bhatt, Adhiratha Boonyasiri, Olivia Boyd, Lorenzo Cattarino, Constanze Ciavarella, Zulma Cucunuba, Gina Cuomo-Dannenburg, Amy Dighe, Ilaria Dorigatti, Sabine L van Elsland, Rich FitzJohn, Katy Gaythorpe, Azra C Ghani, Will Green, Arran Hamlet, Wes Hinsley, Natsuko Imai, David Jorgensen, Edward Knock, Daniel Laydon, Gemma Nedjati-Gilani, Lucy C Okell, Igor Siveroni, Hayley A Thompson, H. Juliette T. Unwin, Robert Verity, Michaela Vollmer, Patrick G T Walker, Yuanrong Wang, Oliver J Watson, Charles Whittaker, Peter Winskill, Christl A Donnelly, Neil M Ferguson, Steven Riley
Publikováno v:
Wellcome Open Research, Vol 5 (2020)
Background: The COVID-19 epidemic was declared a Global Pandemic by WHO on 11 March 2020. By 24 March 2020, over 440,000 cases and almost 20,000 deaths had been reported worldwide. In response to the fast-growing epidemic, which began in the Chinese
Externí odkaz:
https://doaj.org/article/41e4dca62a494f34831ac1205c2d6588
Autor:
Alexandra B Hogan, PhD, Britta L Jewell, PhD, Ellie Sherrard-Smith, PhD, Juan F Vesga, PhD, Oliver J Watson, PhD, Charles Whittaker, MSc, Arran Hamlet, PhD, Jennifer A Smith, DPhil, Peter Winskill, PhD, Robert Verity, PhD, Marc Baguelin, PhD, John A Lees, PhD, Lilith K Whittles, PhD, Kylie E C Ainslie, PhD, Samir Bhatt, DPhil, Adhiratha Boonyasiri, MD, Nicholas F Brazeau, PhD, Lorenzo Cattarino, PhD, Laura V Cooper, MPhil, Helen Coupland, MRes, Gina Cuomo-Dannenburg, MMath, Amy Dighe, MRes, Bimandra A Djaafara, MRes, Christl A Donnelly, ProfScD, Jeff W Eaton, PhD, Sabine L van Elsland, PhD, Richard G FitzJohn, PhD, Han Fu, PhD, Katy A M Gaythorpe, PhD, William Green, MRes, David J Haw, PhD, Sarah Hayes, MSc, Wes Hinsley, PhD, Natsuko Imai, PhD, Daniel J Laydon, PhD, Tara D Mangal, PhD, Thomas A Mellan, PhD, Swapnil Mishra, PhD, Gemma Nedjati-Gilani, PhD, Kris V Parag, PhD, Hayley A Thompson, MPH, H Juliette T Unwin, PhD, Michaela A C Vollmer, PhD, Caroline E Walters, PhD, Haowei Wang, MSc, Yuanrong Wang, Xiaoyue Xi, MSc, Neil M Ferguson, ProfDPhil, Lucy C Okell, PhD, Thomas S Churcher, PhD, Nimalan Arinaminpathy, DPhil, Azra C Ghani, ProfPhD, Patrick G T Walker, PhD, Timothy B Hallett, ProfPhD
Publikováno v:
The Lancet Global Health, Vol 8, Iss 9, Pp e1132-e1141 (2020)
Summary: Background: COVID-19 has the potential to cause substantial disruptions to health services, due to cases overburdening the health system or response measures limiting usual programmatic activities. We aimed to quantify the extent to which di
Externí odkaz:
https://doaj.org/article/c3f23ef3c1124c1993c547ea5ad1e2a8
Autor:
Kylie E C Ainslie, Caroline E. Walters, Han Fu, Sangeeta Bhatia, Haowei Wang, Xiaoyue Xi, Marc Baguelin, Samir Bhatt, Adhiratha Boonyasiri, Olivia Boyd, Lorenzo Cattarino, Constanze Ciavarella, Zulma Cucunuba, Gina Cuomo-Dannenburg, Amy Dighe, Ilaria Dorigatti, Sabine L van Elsland, Rich FitzJohn, Katy Gaythorpe, Azra C Ghani, Will Green, Arran Hamlet, Wes Hinsley, Natsuko Imai, David Jorgensen, Edward Knock, Daniel Laydon, Gemma Nedjati-Gilani, Lucy C Okell, Igor Siveroni, Hayley A Thompson, H Juliette T Unwin, Robert Verity, Michaela Vollmer, Patrick G T Walker, Yuanrong Wang, Oliver J Watson, Charles Whittaker, Peter Winskill, Christl A Donnelly, Neil M Ferguson, Steven Riley
Publikováno v:
Wellcome Open Research, Vol 5 (2020)
Background: The COVID-19 epidemic was declared a Global Pandemic by WHO on 11 March 2020. By 24 March 2020, over 440,000 cases and almost 20,000 deaths had been reported worldwide. In response to the fast-growing epidemic, which began in the Chinese
Externí odkaz:
https://doaj.org/article/c2958b80ed6e410cbfb6d3b2d2176e84
Autor:
Isobel Routledge, Shengjie Lai, Katherine E Battle, Azra C Ghani, Manuel Gomez-Rodriguez, Kyle B Gustafson, Swapnil Mishra, Juliette Unwin, Joshua L Proctor, Andrew J Tatem, Zhongjie Li, Samir Bhatt
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 3, p e1007707 (2020)
In order to monitor progress towards malaria elimination, it is crucial to be able to measure changes in spatio-temporal transmission. However, common metrics of malaria transmission such as parasite prevalence are under powered in elimination contex
Externí odkaz:
https://doaj.org/article/fde608c6e3a14e1399be460d3770a60b
Autor:
John Bradley, Chris Drakeley, Teun Bousema, Joseph D Challenger, Bronner P Gonçalves, Katia Bruxvoort, Alfred B Tiono, Azra C Ghani, Lucy C Okell
Publikováno v:
BMJ Global Health, Vol 4, Iss 6 (2019)
IntroductionArtemether-lumefantrine (AL) is the most widely-recommended treatment for uncomplicated Plasmodium falciparum malaria. Its efficacy has been extensively assessed in clinical trials. In routine healthcare settings, however, its effectivene
Externí odkaz:
https://doaj.org/article/3f52ebc77bed4ef6b2fab24cbc0bef3e
Autor:
Oliver John Watson, Robert Verity, Azra C Ghani, Tini Garske, Jane Cunningham, Antoinette Tshefu, Melchior K Mwandagalirwa, Steven R Meshnick, Jonathan B Parr, Hannah C Slater
Publikováno v:
eLife, Vol 8 (2019)
Ten countries have reported pfhrp2/pfhrp3 gene deletions since the first observation of pfhrp2-deleted parasites in 2012. In a previous study (Watson et al., 2017), we characterised the drivers selecting for pfhrp2/3 deletions and mapped the regions
Externí odkaz:
https://doaj.org/article/ec7f18e440e7433daad632926d7913ad