Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Azra Alajbegovic"'
Autor:
Azra Alajbegovic, Fatima Daoud, Neserin Ali, Katarzyna Kawka, Johan Holmberg, Sebastian Albinsson
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Vascular smooth muscle cell plasticity plays a pivotal role in the pathophysiology of vascular diseases. Despite compelling evidence demonstrating the importance of transcription factor GATA6 in vascular smooth muscle, the functional role of GATA6 re
Externí odkaz:
https://doaj.org/article/74fc50ea83954819b740573266a1b42f
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Aortic aneurysms are defined as an irreversible increase in arterial diameter by more than 50% relative to the normal vessel diameter. The incidence of aneurysm rupture is about 10 in 100,000 persons per year and ruptured arterial aneurysms inevitabl
Externí odkaz:
https://doaj.org/article/3e7e051d47ce4fe7ab1ec5ad6145f9e2
Autor:
Sebastian Albinsson, Mario Grossi, Johan Holmberg, Catarina Rippe, Karl Swärd, Fatima Daoud, Azra Alajbegovic
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims YAP (Yap1) and TAZ (Wwtr1) are transcriptional co-activators and downstream effectors of the Hippo pathway, which play crucial roles in organ size control and cancer pathogenesis. Genetic deletion of YAP/TAZ has shown their critical
Autor:
Fatima, Daoud, Marycarmen, Arévalo Martinez, Johan, Holmberg, Azra, Alajbegovic, Neserin, Ali, Catarina, Rippe, Karl, Swärd, Sebastian, Albinsson
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 42(4)
Hypertension remains a major risk factor for cardiovascular diseases, but the underlying mechanisms are not well understood. We hypothesize that appropriate mechanotransduction and contractile function in vascular smooth muscle cells are crucial to m
Autor:
Sébastien Daudi, Johan Holmberg, Mari Ekman, Gabriella Kalliokoski, Azra Alajbegovic, Sebastian Albinsson, Catarina Rippe, Sigurdur Ragnarsson, Karl Swärd, Fatima Daoud
Publikováno v:
Vascular Pharmacology. 138:106837
Objective Smooth muscle cells contribute significantly to lipid-laden foam cells in atherosclerotic plaques. However, the underlying mechanisms transforming smooth muscle cells into foam cells are poorly understood. The purpose of this study was to g
Autor:
Catarina Rippe, Karin G. Stenkula, Sebastian Albinsson, Maria F. Gomez, Azra Alajbegovic, Karl Swärd
Publikováno v:
The Journal of Physiology. 594:4741-4752
Members of the myocardin family bind to the transcription factor serum response factor (SRF) and act as coactivators controlling genes of relevance for myogenic differentiation and motile function. Binding of SRF to DNA is mediated by genetic element
Autor:
Sebastian Albinsson, Catarina Rippe, Lo Persson, Mario Grossi, Bengt-Olof Nilsson, Amalia Forte, Karl Swärd, Otto Phanstiel, Per Hellstrand, Azra Alajbegovic
Publikováno v:
Journal of Cellular Physiology. 231:1334-1342
Increased vascular smooth muscle cell (VSMC) proliferation is a factor in atherosclerosis and injury-induced arterial (re) stenosis. Inhibition of polyamine synthesis by α-difluoro-methylornithine (DFMO), an irreversible inhibitor of ornithine decar
Publikováno v:
The FASEB Journal. 32
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Frontiers in Physiology
Frontiers in Physiology
Aortic aneurysms are defined as an irreversible increase in arterial diameter by more than 50% relative to the normal vessel diameter. The incidence of aneurysm rupture is about 10 in 100,000 persons per year and ruptured arterial aneurysms inevitabl
Autor:
Thomas Braun, Catarina Rippe, Azra Alajbegovic, Sebastian Albinsson, Karl Swärd, Anirban Bhattachariya, Thomas Boettger, Mari Ekman, Diana Dahan, Per Hellstrand, Tran Thi Hien, Johan Holmberg
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 38(2)
Objective— Pressure-induced myogenic tone is involved in autoregulation of local blood flow and confers protection against excessive pressure levels in small arteries and capillaries. Myogenic tone is dependent on smooth muscle microRNAs (miRNAs),