Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Azna, Zuberi"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
The rise of β-Lactamase mediated antibiotic resistance is a major concern for public health; hence, there is an urgent need to find new treatment approaches. Structure-guided drug repurposing offers a promising approach to swiftly deliver essential
Externí odkaz:
https://doaj.org/article/db80bf1bebb94f74b1c95674b1ad934d
Publikováno v:
Pharmaceuticals, Vol 17, Iss 11, p 1536 (2024)
Background: Histone deacetylase 6 (HDAC6) plays a crucial role in neurological, inflammatory, and other diseases; thus, it has emerged as an important target for therapeutic intervention. To date, there are no FDA-approved HDAC6-targeting drugs, and
Externí odkaz:
https://doaj.org/article/ca47aad20e174abe983f689531fabf57
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
A complex structure known as a biofilm is formed when a variety of bacterial colonies or a single type of cell in a group sticks to a surface. The extracellular polymeric compounds that encase these cells, often consisting of proteins, eDNA, and poly
Externí odkaz:
https://doaj.org/article/1411f881031f496d862f961b177decc1
Autor:
Azna Zuberi, Yongchao Huang, Ariel J. Dotts, Helen Wei, John S. Coon V, Shimeng Liu, Takashi Iizuka, Olivia Wu, Olivia Sotos, Priyanka Saini, Debabrata Chakravarti, Thomas G. Boyer, Yang Dai, Serdar E. Bulun, Ping Yin
Publikováno v:
JCI Insight, Vol 8, Iss 18 (2023)
Uterine leiomyomas cause heavy menstrual bleeding, anemia, and pregnancy loss in millions of women worldwide. Driver mutations in the transcriptional mediator complex subunit 12 (MED12) gene in uterine myometrial cells initiate 70% of leiomyomas that
Externí odkaz:
https://doaj.org/article/d0e7da5cad5e4be6b2a1e703a85ac26f
Publikováno v:
Journal of Biological Research - Thessaloniki, Vol 27, Iss 1, Pp 1-12 (2020)
Abstract Background Biofilm formation is a complex phenomenon of bacterial cells, involved in several human infections. Its formation is regulated and controlled by several protein factors. The BolA-like proteins (bolA gene) are conserved in both pro
Externí odkaz:
https://doaj.org/article/5eb2f378869849099ac20e50ed5e13fb
Autor:
Takashi Iizuka, Ping Yin, Azna Zuberi, Stacy Kujawa, John S. Coon, Richelle D. Björvang, Pauliina Damdimopoulou, Diana C. Pacyga, Rita S. Strakovsky, Jodi A. Flaws, Serdar E. Bulun
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(47)
Uterine leiomyoma is the most common tumor in women and causes severe morbidity in 15 to 30% of reproductive-age women. Epidemiological studies consistently indicate a correlation between leiomyoma development and exposure to endocrine-disrupting che
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::873c4d523e7e6183150a551371fc8726
https://pubmed.ncbi.nlm.nih.gov/36375056
https://pubmed.ncbi.nlm.nih.gov/36375056
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Urinary tract infection (UTI) is one the common infections caused by the recalcitrant nature of biofilms, developed after the pathogen has adhered to the inner lining of the urinary tract. Although significant research has been made in recent years t
Externí odkaz:
https://doaj.org/article/6880af0aa2144bda9e52b3909e35bb69
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Biofilm is a sessile bacterial accretion embedded in self-producing matrix. It is the root cause of about 80% microbial infections in human. Among them, E. coli biofilms are most prevalent in medical devices associated nosocomial infections. The obje
Externí odkaz:
https://doaj.org/article/30ef8f24bf5b4496af87928056ffab6e
Publikováno v:
Current Microbiology. 79
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93def741775db79eaa30c2d7067bcc53
https://doi.org/10.1007/s00284-021-02760-x
https://doi.org/10.1007/s00284-021-02760-x
Publikováno v:
Current microbiology. 79(3)
Biofilm plays an important role in the community and hospital-acquired infections. Especially E. coli biofilm that contributes towards the significant part of medical devices associated with microbial infections. OmpR/EnvZ, a two-component system, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c5f902c73d2a0c084595dc8cde27d59
https://pubmed.ncbi.nlm.nih.gov/35091832
https://pubmed.ncbi.nlm.nih.gov/35091832