Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Aziz A. Khazaeli"'
Autor:
James W. Curtsinger, Aziz A. Khazaeli
Publikováno v:
Demographic Research, Vol 30, p 10 (2014)
BACKGROUNDProgress in understanding senescence requires information about age-dependent changes in individual organisms. However, for experimental systems such as Drosophila melanogaster we usually do not know whether population trajectories are an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff3e5e38f7945354338681e5fa94c50
http://www.demographic-research.org/volumes/vol30/10/30-10.pdf
http://www.demographic-research.org/volumes/vol30/10/30-10.pdf
Autor:
James W. Curtsinger, Aziz A. Khazaeli
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 68:546-553
Populations of Drosophila melanogaster that have been artificially selected for late age of reproduction evolve longer life spans and, in some cases, reduced early fecundity. The negative correlation is widely interpreted as evidence of antagonistic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe8a3479577086189b0135e4c4b5879
https://doi.org/10.1093/gerona/gls226
https://doi.org/10.1093/gerona/gls226
Publikováno v:
Experimental Gerontology. 40:377-385
Among mammals, body size and life span tend to vary inversely within species, but the pattern is less clear in invertebrates. Here, we report on survival and weight of male flies from 29 laboratory strains of Drosophila melanogaster. Natural variatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b7b7f2f6f9edbcb81a8575c3d7f5fbb
https://doi.org/10.1016/j.exger.2005.02.004
https://doi.org/10.1016/j.exger.2005.02.004
Publikováno v:
Genetics. 169:231-242
We measured age-specific metabolic rates in 2861 individual Drosophila melanogaster adult males to determine how genetic variation in metabolism is related to life span. Using recombinant inbred (RI) lines derived from populations artificially select
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::503df863ccdc7bdbb9ddcf8fdd978c68
https://doi.org/10.1534/genetics.104.030403
https://doi.org/10.1534/genetics.104.030403
Publikováno v:
Journal of Insect Physiology. 50:445-453
We examined the association between body mass and metabolic rate in Drosophila melanogaster under a variety of conditions. These included comparisons of body mass and metabolic rate in flies from different laboratory lines measured at different ages,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89ae50e781f1639d7fc1d0f5eba656fd
https://doi.org/10.1016/j.jinsphys.2004.03.002
https://doi.org/10.1016/j.jinsphys.2004.03.002
Publikováno v:
Biogerontology. 5:17-30
An approach towards analyzing survivorship data is proposed for the study of changes in stress resistance with age in the population of Drosophila melanogaster. This is based on the model of heterogeneous mortality (frailty model). Results of the dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74c2513c78bee4f8b88a6074c3eb562b
https://doi.org/10.1023/b:bgen.0000017681.46326.9e
https://doi.org/10.1023/b:bgen.0000017681.46326.9e
Publikováno v:
Journal of Applied Physiology. 95:2605-2613
The use of model organisms, such as Drosophila melanogaster, provides a powerful method for studying mechanisms of aging. Here we report on a large set of recombinant inbred (RI) D. melanogaster lines that exhibit approximately a fivefold range of av
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fade61caf1e667b254c06b8e2e9025ee
https://doi.org/10.1152/japplphysiol.00448.2003
https://doi.org/10.1152/japplphysiol.00448.2003
Autor:
Aziz A. Khazaeli, James W. Curtsinger
Publikováno v:
Mechanisms of Ageing and Development. 123:81-93
We have constructed a set of 120 recombinant inbred lines for use in studies of the genetics of lifespan in Drosophila. The lines are derived from Luckinbill and Clare's (Heredity 55 (1985) 9) artificial selection experiment for increased lifespan. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5feedb023615544f5144601b199a3e5e
https://doi.org/10.1016/s0047-6374(01)00345-1
https://doi.org/10.1016/s0047-6374(01)00345-1
Autor:
James W. Curtsinger, Aziz A. Khazaeli
Publikováno v:
Genetica. 109:245-253
Adult lifespans, age-specific survival, age-specific mortality, survival times on paraquat, and survival times on DDT were assayed in seven lines of Drosophila melanogaster, including two genetically heterogeneous wild lines recently collected from n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bae715c94ab193b0061711b95b22cb13
https://doi.org/10.1023/a:1017569318401
https://doi.org/10.1023/a:1017569318401
Publikováno v:
Mechanisms of Ageing and Development. 105:301-317
Age-specific mortality rates decelerate at older ages in both genetically homogenous and heterogeneous populations of Drosophila . One explanation proposed for deceleration is population heterogeneity. This hypothesis suggests that a population consi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::262a8a7fd5c81e42011f8c42516bef18
https://doi.org/10.1016/s0047-6374(98)00102-x
https://doi.org/10.1016/s0047-6374(98)00102-x