Zobrazeno 1 - 10
of 450
pro vyhledávání: '"Azhar, Rasul"'
Publikováno v:
Translational Oncology, Vol 47, Iss , Pp 102055- (2024)
Breast cancer (BC) is a complex and multifactorial disease, driven by genetic alterations that promote tumor growth and progression. However, recent research has highlighted the importance of non-genetic factors in shaping cancer evolution and influe
Externí odkaz:
https://doaj.org/article/f2a2feba4044479282573d69f7578d68
Publikováno v:
Journal of King Saud University: Science, Vol 36, Iss 8, Pp 103267- (2024)
Alpha-glucosidase inhibitors characterize a major class of Type II antidiabetic drugs and play a significant role in lowering postprandial hyperglycemia. Currently, the market offers a limited number of synthetic inhibitors, highlighting the necessit
Externí odkaz:
https://doaj.org/article/b7d3b100b8004b3791d2ff9a37ac8db3
Autor:
Rabia Akram, Haseeb Anwar, Muhammad Shahid Javed, Ali Imran, Azhar Rasul, Shoaib Ahmad Malik, Mobina Manzoor, Fakhar Islam, Ikram Ullah Khan, Faiqa Sajid, Tehreem Iman, Muhammad Ajmal Shah, Tao Sun, Ghulam Hussain, Mohd Asif Shah
Publikováno v:
International Journal of Food Properties, Vol 26, Iss 1, Pp 894-914 (2023)
ABSTRACTDiabetic peripheral neuropathy is one of the most prevalent complications of diabetes mellitus. It is the most common type of neuropathy characterized by decreased sensory functions in the lower extremities and substantial neuropathic pain. B
Externí odkaz:
https://doaj.org/article/08e7f81e94d248109c3e6055316f0a8f
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Protein inhibitors of activated STATs (PIAS) are proteins for cytokine signaling that activate activator-mediated gene transcription. These proteins, as versatile cellular regulators, have been described as regulators of approximately 60 proteins. Dy
Externí odkaz:
https://doaj.org/article/b2e2345e5d1f41858c1a89fc60b3a03c
Publikováno v:
Scientifica, Vol 2024 (2024)
Diabetes mellitus, a high-morbidity endocrine disease, is typically treated with synthetic hypoglycemic drugs that are costly and have severe side effects. Natural products, like mushrooms, offer a cost-effective, accessible, and eco-friendly alterna
Externí odkaz:
https://doaj.org/article/1f1c6f96483d46439a1a1dcdb9bb67dc
Autor:
Ameer Fawad Zahoor, Sadaf Saeed, Azhar Rasul, Razia Noreen, Ali Irfan, Sajjad Ahmad, Shah Faisal, Sami A. Al-Hussain, Muhammad Athar Saeed, Muhammed Tilahun Muhammed, Zeinab A. Muhammad, Magdi E. A. Zaki
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 3078 (2023)
Molecular hybridization has emerged as the prime and most significant approach for the development of novel anticancer chemotherapeutic agents for combating cancer. In this pursuit, a novel series of indole–1,2,4-triazol-based N-phenyl acetamide st
Externí odkaz:
https://doaj.org/article/94057874409b45f99ff75edfdbf51d9d
Autor:
Rahat Nawaz, Sayed Tayyab Raza Naqvi, Batool Fatima, Nazia Zulfiqar, Muhammad Umer Farooq, Muhammad Najam ul Haq, Dilshad Hussain, Asghar Javeed, Azhar Rasul, Laila Jafri, Saadat Majeed, Waheed Qamar Khan
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract In the present work, nonwoven cotton fabric was modified for antibacterial applications using low-cost and eco-friendly precursors. The treatment of fabric with alkali leads to the formation of active sites for surface modification, followed
Externí odkaz:
https://doaj.org/article/5e1dc1e4dad941a99e4e70470403f0bf
Autor:
Harun Norshidah, Chiuan Herng Leow, Kamarulzaman Ezatul Ezleen, Habibah A. Wahab, Ramachandran Vignesh, Azhar Rasul, Ngit Shin Lai
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
An increase in the occurrence of viral infectious diseases is a global concern for human health. According to a WHO report, dengue virus (DENV) is one of the most common viral diseases affecting approximately 400 million people annually, with worseni
Externí odkaz:
https://doaj.org/article/6a0c4d4e47f6476bade1c0a04e951a18
Autor:
Aneela Khushal, Umar Farooq, Sara Khan, Azhar Rasul, Tanveer A. Wani, Seema Zargar, Sohail Anjum Shahzad, Syed Majid Bukhari, Nazeer Ahmad Khan
Publikováno v:
Molecules, Vol 28, Iss 18, p 6548 (2023)
The major cause of hyperglycemia can generally be attributed to β-glucosidase as per its involvement in non-alcoholic fatty liver disease. This clinical condition leads to liver carcinoma (HepG2 cancer). The phthalimides and phthalamic acid classes
Externí odkaz:
https://doaj.org/article/593ad19a865947ea8e5e61ed898d044d
Publikováno v:
Pharmaceuticals, Vol 16, Iss 7, p 986 (2023)
Cancer therapies based on nanoparticles with a loaded drug can overcome the problem of the drug’s toxic effects in the traditional chemotherapeutic approach. In this study, we loaded LLY-507, a potent inhibitor of SMYD2, a methyltransferase enzyme,
Externí odkaz:
https://doaj.org/article/39e3a386b87f4613b2ceb1a52d2b843e