Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Azeddine Ibrahimi"'
Autor:
Ilham Kandoussi, Ghyzlane El Haddoumi, Mariam Mansouri, Lahcen Belyamani, Azeddine Ibrahimi, Rachid Eljaoudi
Publikováno v:
Bioinformatics and Biology Insights, Vol 18 (2024)
Phosphoinositide-3-kinases (PI3 K) are pivotal regulators of cell signaling implicated in various cancers. Particularly, mutations in the PIK3CA gene encoding the p110α catalytic subunit drive oncogenic signaling, making it an attractive therapeutic
Externí odkaz:
https://doaj.org/article/3b9d2897563444f0803a8eb5e000acaf
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Rahnella perminowiae S11P1 and Variovorax sp. S12S4 are two plant growth-promoting rhizobacteria that were previously isolated from the rhizosphere of Crocus sativus L. (saffron), and have demonstrated interesting PGP activities a
Externí odkaz:
https://doaj.org/article/3dea34b784564fff9ea6368d4cbae242
Autor:
Ghyzlane EL Haddoumi, Mariam Mansouri, Jouhaina Kourou, Lahcen Belyamani, Azeddine Ibrahimi, Ilham Kandoussi
Publikováno v:
Bioinformatics and Biology Insights, Vol 18 (2024)
Tuberculosis (TB) remains a global health challenge with the emergence of drug-resistant Mycobacterium tuberculosis variants, necessitating innovative drug molecules. One potential target is the cell wall synthesis enzyme decaprenylphosphoryl-β-D-ri
Externí odkaz:
https://doaj.org/article/d2dc97ddbb2b42d3b00eeebe7c903c97
Autor:
Nasma Boumajdi, Houda Bendani, Souad Kartti, Tarek Alouane, Lahcen Belyamani, Azeddine Ibrahimi
Publikováno v:
Evolutionary Bioinformatics, Vol 20 (2024)
Genetic variations in the human genome represent the differences in DNA sequence within individuals. This highlights the important role of whole human genome sequencing which has become the keystone for precision medicine and disease prediction. Moro
Externí odkaz:
https://doaj.org/article/9b576eb867294731bcfc8cd2ce5e2ef1
Autor:
El Mokhtar El Ouali, Laurent Bosquet, Boutaina Elgharbaoui, Fatiha Laziri, Ismail Laher, Anthony C. Hackney, Azeddine Ibrahimi, Bouchra Taib, Sanae El Harane, Katja Weiss, Beat Knechtle, Abdelhalem Mesfioui, Hassane Zouhal
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Fatty acid translocase (FAT/CD36) is a transmembrane glycoprotein belonging to the scavenger class B receptor family and is encoded by the cluster of differentiation 36 (CD36) gene. This receptor has a high affinity for fatty acids and is involved in
Externí odkaz:
https://doaj.org/article/acb41fadd7884a50bf1c677772401c80
Autor:
Meryam Magri, El Mehdi Bouricha, Mohammed Hakmi, Rachid EL Jaoudi, Lahcen Belyamani, Azeddine Ibrahimi
Publikováno v:
Bioinformatics and Biology Insights, Vol 17 (2023)
Pseudomonas aeruginosa is a major cause of nosocomial infections and is often associated with biofilm-mediated antibiotic resistance. The LasR protein is a key component of the quorum system in P. aeruginosa , allowing it to regulate its biofilm-indu
Externí odkaz:
https://doaj.org/article/f84142b2c86140e0b30575314a4d5412
Autor:
Souad Kartti, El Mehdi Bouricha, Oumaima Zarrik, Youssef Aghlallou, Chaimaa Mounjid, Rachid ELJaoudi, Lahcen Belyamani, Azeddine Ibrahimi, Basma EL khannoussi
Publikováno v:
Bioinformatics and Biology Insights, Vol 17 (2023)
The increasing commercialization of new gene panels based on next-generation sequencing for clinical research has significantly improved our understanding of breast cancer genetics and has led to the discovery of new mutation variants. The study incl
Externí odkaz:
https://doaj.org/article/9cc1acd2e4224753a301870ee2b969c3
Autor:
Ghyzlane EL Haddoumi, Mariam Mansouri, Houda Bendani, Mohammed Walid Chemao-Elfihri, Jouhaina Kourou, Hanane Abbou, Lahcen Belyamani, Ilham Kandoussi, Azeddine Ibrahimi
Publikováno v:
Bioinformatics and Biology Insights, Vol 17 (2023)
Dihydrofolate reductase (DHFR) is a crucial enzyme that catalyzes the conversion of folic acid. Its reserved properties and significance in both human (h-DHFR) and mycobacterium (mt-DHFR) make it a challenging target for developing drugs against canc
Externí odkaz:
https://doaj.org/article/c9eaad587cf24ab58195360779414f6c
Autor:
Mariam Mansouri, Ghyzlane El Haddoumi, Houda Bendani, Nasma Boumajdi, Mohammed Hakmi, Hanane Abbou, El Mehdi Bouricha, Boutaina Elgharbaoui, Souad Kartti, Rachid El Jaoudi, Lahcen Belyamani, Ilham Kandoussi, Azeddine Ibrahimi, Naima El Hafidi
Publikováno v:
Evolutionary Bioinformatics, Vol 19 (2023)
Autosomal dominant hyper-IgE syndrome (AD-HIES) is linked to dominant negative mutations of the STAT3 protein whose molecular basis for dysfunction is unclear and presenting with a variety of clinical manifestations with only supportive treatment. To
Externí odkaz:
https://doaj.org/article/c83c4e877e6045fea833a4e5d52c3e45
Autor:
Amal Zouaki, Hakima Kabbaj, Ghizlane El Amin, Mouna Ouadghiri, Bouchra Belefquih, Azeddine Ibrahimi, Myriam Seffar
Publikováno v:
Advances in Virology, Vol 2023 (2023)
SARS-CoV-2 is a major public health problem worldwide. Since its emergence, several diagnostic kits have been developed to ensure rapid patient management. The aim of our study is to check the performance of the new Moroccan SARS-CoV-2 detection kit:
Externí odkaz:
https://doaj.org/article/35d4ed8297fb4a3a895788beec866e9b