Detection of endogenous translesion DNA synthesis in single mammalian cells

Autor: Egger, Tom, Aze, Antoine, Maiorano, Domenico

Publikováno v: In Cell Reports Methods 26 June 2023 3(6)

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Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites

Autor: Zellweger, Ralph, Chauvin, Maëva, Bec, Nicole, Larroque, Christian, Lopes, Massimo, Basbous, Jihane, Aze, Antoine, CHALOIN, Laurent, Lebdy, Rana, Hodroj, Dana, Ribeyre, Cyril, Larroque, Marion, Shepard, Caitlin, Kim, Baek, Pruvost, Alain, Moreaux, Jérôme, Maiorano, Domenico, Méchali, Marcel, Constantinou, Angelos

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, 2020, 48 (4), pp.1886-1904. ⟨10.1093/nar/gkz1162⟩
Nucleic Acids Research, Oxford University Press, 2020, 48 (4), pp.1886-1904. ⟨10.1093/nar/gkz1162⟩

Metabolic alterations support cellular transformation. Noticeably, cellular transformation and cancer progression is associated with accumulation of dihydrouracil and dihydrothymine. However, it remains elusive how dihydropyrimidine metabolites affec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dcae2cf4dd3e7e5ccc59a4dd71160f1
https://hal.science/hal-02556387

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Characteristics of Metazoan DNA Replication Origins

Autor: Hutchins, James R. A., Aze, Antoine, Coulombe, Philippe, Méchali, Marcel

Publikováno v: DNA Replication, Recombination, and Repair

DNA replication in metazoan cells initiates at multiple discrete chromosomal sites called replication origins. Recent genome-wide studies have mapped thousands of origins in animal and plant cells, but without yielding a distinct and universal consen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmc_________::101d7707bdfaebfe43e58e37480af2ac
http://europepmc.org/articles/PMC7120227