Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Azar Dashti"'
Autor:
Yongxin Yu, Kristian F. Hanssen, Hanne Scholz, Timothy J. Lyons, Joshua J. Wang, Tore Henriksen, M. K. Menard, K. May, Azar Dashti, K. Lu, Christopher E. Aston, John R. Stanley, Alicia J. Jenkins, Alison Nankervis, Samar M. Hammad, Torun Clausen, Bjorg Lorentzen, Jian Xing Ma, J. C. Scardo, Sarah X. Zhang, Satish K. Garg
Publikováno v:
Diabetologia. 52:160-168
Elevated anti-angiogenic factors such as soluble fms-like tyrosine kinase 1 (sFlt1), a soluble form of vascular endothelial growth factor receptor, and endoglin, a co-receptor for TGFbeta1, confer high risk of pre-eclampsia in healthy pregnant women.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8cd35c81ffded9c8728f952c5559ce
https://doi.org/10.1007/s00125-008-1182-x
https://doi.org/10.1007/s00125-008-1182-x
Autor:
Azar Dashti, Peng Zhai, Xinli Lin, Shili Wu, Xuejun C. Zhang, Deborah Downs, Yujun Pan, Xinjuan Wang, Yong-Tae Kim
Publikováno v:
European Journal of Biochemistry. 269:5668-5677
BACE2 (Memapsin 1) is a membrane-bound aspartic protease that is highly homologous with BACE1 (Memapsin 2). While BACE1 processes the amyloid precursor protein (APP) at a key step in generating the β-amyloid peptide and presumably causes Alzheimer's
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21df60d01be7d9d06ffd018c99752cf5
https://doi.org/10.1046/j.1432-1033.2002.03277.x
https://doi.org/10.1046/j.1432-1033.2002.03277.x
Publikováno v:
Proceedings of the National Academy of Sciences. 97:1456-1460
The cDNAs of two new human membrane-associated aspartic proteases, memapsin 1 and memapsin 2, have been cloned and sequenced. The deduced amino acid sequences show that each contains the typical pre , pro , and aspartic protease regions, but each als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe2e9e8b8edd1da1a1c06d7a6d134c1e
https://doi.org/10.1073/pnas.97.4.1456
https://doi.org/10.1073/pnas.97.4.1456
Autor:
Jian Xing Ma, Albina Gosmanova, Azar Dashti, Sarah X. Zhang, M Z Baker, Christopher E. Aston, Alicia J. Jenkins, Timothy J. Lyons
Publikováno v:
Diabetes Research and Clinical Practice. 82:e5-e7
Serum PEDF levels (mean (S.D.)) were increased in 96 Type 2 diabetic vs. 54 non-diabetic subjects; 5.3 (2.8) vs. 3.2 (2.0)mug/ml, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00e575f16d897227c718db191fca0a1
https://doi.org/10.1016/j.diabres.2008.06.019
https://doi.org/10.1016/j.diabres.2008.06.019
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1302:224-230
A full-length recombinant human apolipoprotein C-II (ApoC-II) has been successfully expressed in Escherichia coli using the T7 expression system. The recombinant ApoC-II. which was expressed intracellularly in the inclusion bodies, was solubilized wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848d362ffb869cb685c02c0ef7077548
https://doi.org/10.1016/0005-2760(96)00065-3
https://doi.org/10.1016/0005-2760(96)00065-3
Autor:
Christopher E. Aston, Samar M. Hammad, Alison Nankervis, Torun Clausen, Kristian F. Hanssen, Tore Henriksen, James A. Scardo, Arpita Basu, Bjørg Lorentzen, Petar Alaupovic, M. Kathryn Menard, Hanne Scholz, Timothy J. Lyons, Azar Dashti, John R. Stanley, Satish K. Garg, Mingyuan Wu, Alicia J. Jenkins, Yongxin Yu
Publikováno v:
The Journal of clinical endocrinology and metabolism. 97(5)
In nondiabetic pregnancy, cross-sectional studies have shown associations between maternal dyslipidemia and preeclampsia (PE). In type 1 diabetes mellitus (T1DM), the prevalence of PE is increased 4-fold, but prospective associations with plasma lipo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a8ef2bb9851e642af76c60348bbbe6
https://pubmed.ncbi.nlm.nih.gov/22438226
https://pubmed.ncbi.nlm.nih.gov/22438226
Publikováno v:
The FASEB Journal. 7:1070-1080
A potential gene therapy strategy against human immunodeficiency virus (HIV-1) is to disrupt the intracellular transport of viral proteins. We report here the binding and transporting of HIV-1 glycoprotein gp160 to lysosomes as a result of the expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119897599c699ca48d13818005e2a811
https://doi.org/10.1096/fasebj.7.11.8370478
https://doi.org/10.1096/fasebj.7.11.8370478
Autor:
Kenneth Wilson, Ming-Hui Zou, Timothy J. Lyons, Joshua J. Wang, Azar Dashti, Jian Xing Ma, Sarah X. Zhang, Luke I. Szweda
Publikováno v:
Journal of molecular endocrinology. 41(3)
Oxidized and/or glycated low-density lipoprotein (LDL) may mediate capillary injury in diabetic retinopathy. The mechanisms may involve pro-inflammatory and pro-oxidant effects on retinal capillary pericytes. In this study, these effects, and the pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeb262dada9c6a95c0193db43a6593db
https://pubmed.ncbi.nlm.nih.gov/18586837
https://pubmed.ncbi.nlm.nih.gov/18586837
Autor:
George L. Dale, M Z Baker, Kerri D. May, Azar Dashti, Alicia J. Jenkins, Timothy J. Lyons, Leann Olansky, Christopher E. Aston, Albina Gosmanova
Publikováno v:
Diabetes research and clinical practice. 81(2)
Coated-platelet levels were quantified in 58 people with Type 1 diabetes, 90 with Type 2 diabetes, and 54 non-diabetic controls. In diabetes high coated-platelet levels were related to smoking and glucose control drugs, but not to glycaemia or other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d157127651c0784cbc0613cb87be63f9
https://pubmed.ncbi.nlm.nih.gov/18508150
https://pubmed.ncbi.nlm.nih.gov/18508150
Autor:
Weiwei Song, Jeremy L. Barth, Yongxin Yu, W. S. Argraves, Kangmo Lu, Y. Huang, Timothy J. Lyons, Azar Dashti
Publikováno v:
Diabetologia. 50(10)
Aims/hypothesis Matrix metalloproteinases (MMPs) and their natural inhibitors, tissue inhibitor of metalloproteinases (TIMPs), regulate important biological processes including the homeostasis of the extracellular matrix, proteolysis of cell surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c0248ba8722e9988ab5b39774880c4
https://pubmed.ncbi.nlm.nih.gov/17676308
https://pubmed.ncbi.nlm.nih.gov/17676308