Fluid–structure interaction modelling of a positive-displacement Total Artificial Heart

Autor: Joseph Bornoff, Azad Najar, Libera Fresiello, Thomas Finocchiaro, Ina Laura Perkins, Harinderjit Gill, Andrew N. Cookson, Katharine H. Fraser

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)

Abstract For those suffering from end-stage biventricular heart failure, and where a heart transplantation is not a viable option, a Total Artificial Heart (TAH) can be used as a bridge to transplant device. The Realheart TAH is a four-chamber artifi

Externí odkaz: https://doaj.org/article/834932446ffb481f83c77608cbb18048

Hemodynamic characterization of the Realheart® total artificial heart with a hybrid cardiovascular simulator

Autor: Libera Fresiello, Azad Najar, Nils Brynedal Ignell, Krzysztof Zieliński, Maria Rocchi, Bart Meyns, Ina Laura Perkins

Publikováno v: Artificial Organs. 46:1585-1596

Heart failure is a growing health problem worldwide. Due to the lack of donor hearts there is a need for alternative therapies, such as total artificial hearts (TAHs). The aim of this study is to evaluate the hemodynamic performance of the Realheart�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe12304092dbec947e14db74b228a08
https://doi.org/10.1111/aor.14223

Video-based valve motion combined with computational fluid dynamics gives stable and accurate simulations of blood flow in the Realheart total artificial heart

Autor: Nils Brynedal Ignell, Libera Fresiello, Danny McCree, Nathaniel Kelly, Katharine Fraser, Ina Laura Perkins, Azad Najar, Andrew Cookson

Publikováno v: Kelly, N S, McCree, D, Fresiello, L, Brynedal Ignell, N, Cookson, A N, Najar, A, Perkins, I L & Fraser, K H 2022, ' Video-based valve motion combined with computational fluid dynamics gives stable and accurate simulations of blood flow in the Realheart total artificial heart ', Artificial Organs, vol. 46, no. 1, pp. 57-70 . https://doi.org/10.1111/aor.14056
Kelly, N, McCree, D, Fresiello, L, Ignell, N, Cookson, A, Najar, A, Perkins, I L & Fraser, K 2022, ' Video based valve motion combined with Computational Fluid Dynamics gives stable and accurate simulations of blood flow in the Realheart® Total Artificial Heart ', Artificial Organs, vol. 46, no. 1, pp. 57-70 . https://doi.org/10.1111/aor.14056

BACKGROUND: Patients with end-stage, biventricular heart failure, and for whom heart transplantation is not an option, may be given a Total Artificial Heart (TAH). The Realheart® is a novel TAH which pumps blood by mimicking the native heart with tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b88891c4637a5b5292b56ef9c2170c7
https://lirias.kuleuven.be/handle/20.500.12942/703141

P70: Evaluation Of A Novel Virtual Implantation Tool For The External Design Optimization Of The Realheart TAH

Autor: Oliver Chu, Ina Laura Perkins, Thomas Finocchiaro, Azad Najar

Publikováno v: ASAIO Journal. 68:133-133

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c00993751d00af20bdec24cd9cbc7ff0
https://doi.org/10.1097/01.mat.0000841496.22312.77

Virtual implantations to transition from porcine to bovine animal models for a total artificial heart

Autor: Simon J. Sonntag, Bart Meyns, Ina Laura Pieper, Göran Hellers, Fredrik Pahlm, Henrik Casimir Ahn, Azad Najar

Publikováno v: Artificial organsREFERENCES. 44(4)

Realheart total artificial heart (TAH) is a novel, pulsatile, four-chamber total artificial heart which had been successfully tested acutely in a porcine animal model. However, the bovine model is better suited for long-term testing and thus an evalu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43307b2b784a439c0196c78c69978361
https://pubmed.ncbi.nlm.nih.gov/31596507