Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Ayyappan Nair"'
Autor:
Mohit Sharma, Subramania Iyer, Kishore P., Jimmy Mathew, Raghuveer Reddy, Janarthanan Ramu, Sundeep Vijayaraghavan, Abhijeet Wakure, Chetan Mali S M., Visakh Varma, Ashish Chaudhari, Swapnil Dhake, Akshay Omkumar, Jerry Paul, Sunil Rajan, Ayyappan Nair, Druvan Shaji
Publikováno v:
Indian Journal of Plastic Surgery, Vol 50, Iss 02, Pp 153-160 (2017)
Introduction: This article deals with two patients who underwent bilateral hand transplantation following amputation of both upper limbs at the distal third of the foream. Materials and Methods: The first patient had a history of loss of hands in a t
Externí odkaz:
https://doaj.org/article/6a178c0f5e76451daf02acc3c3ec9ade
Publikováno v:
Journal of Orthopaedic Case Reports. 12:69-75
Introduction: Luxatio erecta femoris or inferior hip dislocation is the rarest type of hip dislocation. It can be caused by a severe trauma to the hip and the mechanism of injury is often very complex. Very few cases have been reported in the literat
Publikováno v:
Journal of Evidence Based Medicine and Healthcare, Vol 3, Iss 78, Pp 4215-4218 (2016)
BACKGROUND Osteoarthritis is the most common type of arthritis. It is a degenerative disease where, load bearing synovial joints like hip and knee are affected. Usually bilateral, highest incidence is seen after 6th decade of life. It is also common
Publikováno v:
Journal of Evidence Based Medicine and Healthcare, Vol 3, Iss 78, Pp 4226-4229 (2016)
BACKGROUND Around three lakh accidents occur in India every year injuring upto 3,40,000 people. Injuries to the pedestrian occur as a result of acceleration process. There can be an abrasion, contusion, laceration or fracture. Injuries can be grouped
Autor:
Ganesh Sambasivam, Sunilkumar Sukumaran, Subbulakshmi Karthikeyan, Gunja Gupta, Ayyappan Nair, Saiful F. Haq, Shalaka Samant
Publikováno v:
Journal of Industrial Microbiology and Biotechnology. 41:1435-1442
Recombinant proteins can be targeted to the Escherichia coli periplasm by fusing them to signal peptides. The popular pET vectors facilitate fusion of target proteins to the PelB signal. A systematic comparison of the PelB signal with native E. coli
Publikováno v:
Zebrafish. 11:154-166
Compounds routinely used to increase the quality of life and combat disease undergo stringent potency and biosafety tests before approval. However, based on the outcome of ongoing research, new norms need to be effected to ensure that the compounds c
Publikováno v:
Journal of Virological Methods. 153:269-272
A robust assay to titer lentiviral vectors is imperative to qualifying their use in drug discovery, target validation and clinical applications. In this study, a novel branched DNA based hybridization assay was developed to titer lentiviral vectors b
Autor:
Laura Shaughnessy, Ayyappan Nair, Frank Koentgen, Beth Chamblin, Ram Ramabhadran, Mary Beth Thomas, John Wakefield
Publikováno v:
Current Alzheimer Research. 2:239-247
Lentiviral vectors are efficient tools for the introduction of genes into a wide range of established and primary cells in vitro, ex vivo, and in vivo, and also permit efficient transgenesis in a wide range of mammalian species. Our goals have been t
Autor:
Warren J. Strittmatter, James R. Burke, S. Y. Bae, Carol A. Colton, Ayyappan Nair, Q. Xu, J. K. Wakefield, Michael P. Vitek
Publikováno v:
The Journal of Neuroscience. 24:7118-7127
Our data suggest a novel mechanism whereby pathological-length polyglutamine (polyQ) proteins promote the spermine synthetic pathway, increasing polyQ-aggregation and cell death. As detected in a cell-free turbidity assay, spermine promotes aggregati
Autor:
Frank Koentgen, John Wakefield, Laura Shaughnessy, Beth Chamblin, Ayyappan Nair, Lori L. McMahon, Mary Beth Thomas, Ram Ramabhadran
Publikováno v:
Journal of Molecular Neuroscience. 24:023-032
Development of therapeutics for Alzheimer's disease (AD) requires appropriate cell culture models that reflect the errant biochemical pathways and animal models that reflect the pathological hallmarks of the disease as well as the clinical manifestat