Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ayush K. Srivastava"'
Autor:
Fabian Hoelzgen, Thuy T. P. Nguyen, Elina Klukin, Mohamed Boumaiza, Ayush K. Srivastava, Elizabeth Y. Kim, Ran Zalk, Anat Shahar, Sagit Cohen-Schwartz, Esther G. Meyron-Holtz, Fadi Bou-Abdallah, Joseph D. Mancias, Gabriel A. Frank
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract The interaction between nuclear receptor coactivator 4 (NCOA4) and the iron storage protein ferritin is a crucial component of cellular iron homeostasis. The binding of NCOA4 to the FTH1 subunits of ferritin initiates ferritinophagy—a ferr
Externí odkaz:
https://doaj.org/article/e4a516c83d304a99b368f05ce7ce2660
Autor:
Ayush K. Srivastava, Aliaksandra A. Reutovich, Nathan J. Hunter, Paolo Arosio, Fadi Bou-Abdallah
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Ferritin is a ubiquitous intracellular iron storage protein that plays a crucial role in iron homeostasis. Animal tissue ferritins consist of multiple isoforms (or isoferritins) with different proportions of H and L subunits that contribute
Externí odkaz:
https://doaj.org/article/0ec83e8949494934b78127fd60be7757
Autor:
Aliaksandra A. Reutovich, Ayush K. Srivastava, Gideon L. Smith, Alexandre Foucher, Douglas M. Yates, Eric A. Stach, Georgia C. Papaefthymiou, Paolo Arosio, Fadi Bou-Abdallah
Publikováno v:
Biochemistry. 61(19)
Ferritins are highly conserved supramolecular protein nanostructures that play a key role in iron homeostasis. Thousands of iron atoms can be stored inside their hollow cavity as a hydrated ferric oxyhydroxide mineral. Although phosphate associates w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d50ad57f345fca07ecea2e3b6c9e2ad
https://pubmed.ncbi.nlm.nih.gov/36099002
https://pubmed.ncbi.nlm.nih.gov/36099002
Publikováno v:
Protein science : a publication of the Protein SocietyREFERENCES. 32(1)
Mammalian ferritins are predominantly heteropolymeric species consisting of 2 structurally similar, but functionally and genetically distinct subunit types, called H (Heavy) and L (Light). The two subunits co-assemble in different H and L ratios to f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f628f0269e7845a8f844276fbd6cdca
https://pubmed.ncbi.nlm.nih.gov/36519270
https://pubmed.ncbi.nlm.nih.gov/36519270
Autor:
Thomas Longo, Steve Kim, Ayush K. Srivastava, Lauren Hurley, Kaixuan Ji, Arthur J. Viescas, Nicholas Flint, Alexandre C. Foucher, Douglas Yates, Eric A. Stach, Fadi Bou-Abdallah, Georgia C. Papaefthymiou
Publikováno v:
Nanoscale advances. 5(1)
The physical properties of in vitro iron-reconstituted and genetically engineered human heteropolymer ferritins were investigated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890ac7217c68725177bb46747a22f563
https://pubmed.ncbi.nlm.nih.gov/36605807
https://pubmed.ncbi.nlm.nih.gov/36605807
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1867:130288
The development of safe and effective vaccines against SARS-CoV-2 and other viruses with high antigenic drift is of crucial importance to public health. Ferritin is a well characterized and ubiquitous iron storage protein that has emerged not only as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794cdd7dad1b20d1fa65cb627d8cf8e7
https://doi.org/10.1016/j.bbagen.2022.130288
https://doi.org/10.1016/j.bbagen.2022.130288
Autor:
Gideon L. Smith, Ayush K. Srivastava, Aliaksandra A. Reutovich, Nathan J. Hunter, Paolo Arosio, Artem Melman, Fadi Bou-Abdallah
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 11; Pages: 6100
Most in vitro iron mobilization studies from ferritin have been performed in aqueous buffered solutions using a variety of reducing substances. The kinetics of iron mobilization from ferritin in a medium that resembles the complex milieu of cells cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2092e8e58224ce70887920b8a24235d4
https://pubmed.ncbi.nlm.nih.gov/35682778
https://pubmed.ncbi.nlm.nih.gov/35682778