Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ayumu Sakai"'
Publikováno v:
Canadian Journal of Fisheries and Aquatic Sciences. 74:812-823
Three growth-based survival mechanisms were tested for multiple cohorts of Japanese anchovy (Engraulis japonicus) larvae in Sagami Bay. Through otolith microstructure analysis, growth trajectories and histories of samples of the survivors were compar
Publikováno v:
Composites Science and Technology. 71:1098-1104
The present study demonstrates a novel mixing approach for achieving a good dispersion of carbon nanotubes (CNTs) in a styrene–butadiene rubber (SBR), which leads to a significant improvement in electrical properties. Our mixing technique consists
Autor:
Naohiko Uchida, Ayumu Sakai, Yoshikatsu Fujisawa, Mitsutoshi Yamamoto, Yuji Tanaka, Akihiro Kanzaki, Shigetoshi Kuroda, Hiroshi Ujike
Publikováno v:
The American Journal of Geriatric Psychiatry. 13:1062-1066
Objective Some preclinical evidence suggests that the sigma receptor type 1, which plays several roles in learning and memory, may also be involved in the pathogenesis of Alzheimer disease (AD). The authors provide here genetic evidence that the sigm
Autor:
Kenji Nakata, Naohiko Uchida, Akihiro Kanzaki, Yoshikatsu Fujisawa, Kazuya Okumura, Ayumu Sakai, Mitsutoshi Yamamoto, Yasushi Takehisa, Hiroshi Ujike, Shigetoshi Kuroda, Takaki Imamura
Publikováno v:
Dementia and Geriatric Cognitive Disorders. 17:164-169
Neprilysin (NEP), also known as neutral endopeptidase, enkephalinase, CD 10, and common acute lymphoblastic leukemia antigen, is a 97-kD protein. NEP can degrade amyloid β peptides, and its mRNA and protein levels are known to be reduced in the brai
Autor:
Takamitsu Nakano, Takaki Imamura, Yuji Tanaka, Naohiko Uchida, Shigetoshi Kuroda, Ayumu Sakai, Manabu Takaki, Akira Nomura, Takeshi Katsu, Hiroshi Ujike, Kenji Nakata
Publikováno v:
Neuroscience Letters. 353:53-56
Neurodevelopmental abnormalities have been reported in studies on the pathogenesis of schizophrenia. The Wnt-signaling pathway has been implicated in a variety of processes in neurodevelopment, and the frizzled proteins have been identified as recept
Autor:
Takashi Hamamura, Takaki Imamura, Hiroshi Ujike, Yuji Tanaka, Akira Nomura, Kenji Nakata, Shigetoshi Kuroda, Naohiko Uchida, Ayumu Sakai, Takeshi Katsu
Publikováno v:
Neuroscience Letters. 337:17-20
Brain-derived neurotrophic factor (BDNF) belongs to a family of neurotrophic factors and has been demonstrated to promote the survival, differentiation, and maintenance of a broad variety of central nervous system neurons. Several reports have sugges
Autor:
Hiroshi Ujike, Toru Hori, Masaomi Iyo, Norio Ozaki, Tokutaro Komiyama, Ayumu Sakai, Toshiya Inada, Ichiro Sora, Kyohei Otani, Nakao Iwata, Mitsuhiko Yamada, Tatsuya Kotaka, Yuko Okahisa, Shigetoshi Kuroda, Yoshimoto Sekine, Mutsuo Harano
Publikováno v:
Neuroscience letters. 434(1)
Because methamphetamine (METH) is metabolized by CYP2D6 at the first step of hydroxylation and demethylation, it is possible that functional variants of CYP2D6 alter susceptibility to methamphetamine-induced dependence. We genotyped CYP2D6*1, *4, *5,
Autor:
Mutsuo Harano, Mitsuhiko Yamada, Norio Ozaki, Ichiro Sora, Tokutaro Komiyama, Yuji Tanaka, Hiroshi Ujike, Masaomi Iyo, Shigetoshi Kuroda, T. Inada, Yoshimoto Sekine, Nakao Iwata, Toru Hori, T. Kodaka, Ayumu Sakai, Yuko Okahisa, Kenji Nakata
Publikováno v:
Annals of the New York Academy of Sciences. 1074
Dihydropyrimidinase-related protein 2 (DRP-2 or DPYSL-2)mediates the intracellular response to collapsin, a repulsive extracellular guidance cue or axonal outgrowth. DRP-2 is also referred to as collapsin response mediator protein 2 (CRMP-2). We have
Autor:
Toshiya Inada, Ayumu Sakai, Mutsuo Harano, Kyohei Ohtani, Naohiko Uchida, Hiroshi Ujike, Makiko Kishimoto, Ichiro Sora, Yukitaka Morita, Tokutaro Komiyama, Norio Ozaki, Takaki Imamura, Shigetoshi Kuroda, Akira Nomura, Nakao Iwata, Yoshimoto Sekine, Mitsuhiko Yamada, Akiko Morio, Yuji Tanaka, Masaomi Iyo
Publikováno v:
Neuroscience letters. 376(3)
Genetic contributions to the etiology of substance abuse and dependence are topics of major interest. Acute and chronic cannabis use can produce drug-induced psychosis resembling schizophrenia and worsen positive symptoms of schizophrenia. The endoca
Autor:
Shigetoshi Kuroda, Naohiko Uchida, Yasushi Takehisa, Yoshikatsu Fujisawa, Kenji Nakata, Hiroshi Ujike, Takaki Imamura, Mitsutoshi Yamamoto, Akihiro Kanzaki, Kazuya Okumura, Ayumu Sakai
Publikováno v:
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. (1)
Susceptibility to Alzheimer's disease (AD) is thought to be regulated by multiple genetic factors. Recently, three independent studies have reported that loci on chromosome 10q are linked with AD, and the insulin degrading enzyme (IDE; MIM 146680) ge