Výsledky vyhledávání - "Ayumu Kadota"

Akademický článek

Aqueous Extract from Leaves of Citrus unshiu Attenuates Lipopolysaccharide-Induced Inflammatory Responses in a Mouse Model of Systemic Inflammation

Autor: Kosuke Nishi, Takako Ito, Ayumu Kadota, Momoko Ishida, Hisashi Nishiwaki, Naohiro Fukuda, Naoaki Kanamoto, Yoko Nagata, Takuya Sugahara

Publikováno v: Plants, Vol 10, Iss 8, p 1708 (2021)

Inflammation is related to various life-threatening diseases including cancer, neurodegenerative diseases, and metabolic syndrome. Because macrophages are prominent inflammatory cells, regulation of macrophage activation is a key issue to control the

Externí odkaz: https://doaj.org/article/cb0bbe28ee624539ac7658791063b0a3

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Akademický článek

Nobiletin suppresses monocyte chemoattractant protein-1 (MCP-1) expression by regulating MAPK signaling in 3T3-L1 cells

Autor: Sho Yasunaga, Miku Domen, Kosuke Nishi, Ayumu Kadota, Takuya Sugahara

Publikováno v: Journal of Functional Foods, Vol 27, Iss , Pp 406-415 (2016)

Nobiletin is a major citrus flavonoid possessing several biological activities. Nobiletin has been reported to display anti-inflammatory activity and to reduce monocyte chemoattractant protein (MCP)-1 secretion by 3T3-L1 adipocytes. However, its mode

Externí odkaz: https://doaj.org/article/37c8d5255b734a4ea047976ed55cdeab

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Akademický článek

Effect of concurrent administration of nobiletin and β-lactoglobulin on the symptoms of Japanese cedar pollinosis models in mice

Autor: Sho Yasunaga, Ayumu Kadota, Taizo Kikuchi, Chiaki Kubo, Kosuke Nishi, Takuya Sugahara

Publikováno v: Journal of Functional Foods, Vol 22, Iss , Pp 389-397 (2016)

Nobiletin and β-lactoglobulin were previously demonstrated to suppress mast cell de-granulation in vitro and in vivo. In this study, the multiple anti-allergic effects of both substances by simultaneous treatment were examined in order to determine

Externí odkaz: https://doaj.org/article/c67949f194414739bd8ff857ad5ef60c

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Akademický článek

Nobiletin, a polymethoxy flavonoid, exerts anti-allergic effect by suppressing activation of phosphoinositide 3-kinase

Autor: Sayo Onishi, Kosuke Nishi, Sho Yasunaga, Ayako Muranaka, Kazutaka Maeyama, Ayumu Kadota, Takuya Sugahara

Publikováno v: Journal of Functional Foods, Vol 6, Iss , Pp 606-614 (2014)

Nobiletin is a polymethoxy flavonoid present in fruit tissues of citrus species and has been reported to suppress degranulation of RBL-2H3 cells. However, the detailed mechanism is still unknown. In this study the mechanism of suppressive effect of n

Externí odkaz: https://doaj.org/article/f3bade15e04b4126bc83b86aee3c3c02

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Akademický článek

Immunomodulatory effects of citrus fruit auraptene in vitro and in vivo

Autor: Sogo Nishimoto, Ayako Muranaka, Kosuke Nishi, Ayumu Kadota, Takuya Sugahara

Publikováno v: Journal of Functional Foods, Vol 4, Iss 4, Pp 883-890 (2012)

Effects of auraptene on immune cells in vitro and in vivo were examined. IgM production by human hybridoma HB4C5 cells was enhanced by auraptene. Auraptene also stimulated IgA and IgG production by mouse primary splenocytes, and IgA and IgM productio

Externí odkaz: https://doaj.org/article/d48b98db55cd4bfcbe362f23cdf5175a

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Akademický článek

Immunostimulatory effect of β-cryptoxanthin in vitro and in vivo

Autor: Kosuke Nishi, Ayako Muranaka, Sogo Nishimoto, Ayumu Kadota, Takuya Sugahara

Publikováno v: Journal of Functional Foods, Vol 4, Iss 3, Pp 618-625 (2012)

Beta-cryptoxanthin (β-Crp), a mono-hydroxylated β-carotene, is a major dietary provitamin A xanthophyll. The immunostimulatory effect of β-Crp was examined using human hybridoma HB4C5 cells and mouse primary lymphocytes in vitro and using mice in

Externí odkaz: https://doaj.org/article/56be7b12b4a94e7b942255ece0d00dca

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