Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ayumi Takeshita"'
Autor:
Ayumi Takeshita, Norifumi Morikawa, Yuta Yokoyama, Yasuo Takeda, Erika Watanabe, Kazuro Ikawa, Akari Shigemi, Kazuaki Matsumoto
Publikováno v:
Journal of Infection and Chemotherapy. 21:70-73
Linezolid pharmacokinetic profile in pediatric patients has not been fully characterized, and the dose needed to achieve a pharmacokinetic-pharmacodynamic (PK-PD) target has yet to be established because its efficacy is associated with the area under
Publikováno v:
Shokubutsu Kankyo Kogaku. 20:242-246
施肥量の違いがミズナの生育と硝酸イオン濃度に及ぼす影響を,同じアブラナ科で硝酸イオン濃度が高い葉菜類の一つであるコマツナを比較対象として検討した.施肥処理は大塚A処方0.5
Publikováno v:
Molecular and Cellular Biology. 24:1313-1323
Most cis-acting regulatory elements have generally been assumed to activate a single nearby gene. However, many genes are clustered together, raising the possibility that they are regulated through a common element. We show here that a single peroxis
Autor:
Katsushi Yamada, Norifumi Morikawa, Kazuaki Matsumoto, Akari Shigemi, Yasuo Takeda, Keiko Yaji, Yoshihiro Shimodozono, Kazuro Ikawa, Ayumi Takeshita
Publikováno v:
International Journal of Antimicrobial Agents. 36:179-181
The major adverse event associated with linezolid treatment is reversible myelosuppression, mostly thrombocytopenia. Recent studies have reported that the incidence of linezolid-induced thrombocytopenia was higher in patients with renal failure than
Autor:
Kazuaki Matsumoto, Yasuo Takeda, Erika Watanabe, Akari Shigemi, Yuta Yokoyama, Norifumi Morikawa, Kazuro Ikawa, Ayumi Takeshita
Publikováno v:
International journal of antimicrobial agents. 44(3)
The pharmacokinetic/pharmacodynamic (PK/PD) index for the efficacy of linezolid is a 24-h area under the plasma drug concentration-time curve (AUC₂₄)/minimum inhibitory concentration (MIC) ratio of ≥100. The main adverse event associated with a
Autor:
Tanetoshi Koyama, Ayumi Takeshita, Kazuhiro Saito, Kyozo Ogura, Tokuzo Nishino, Masami Osabe, Shusei Obata
Publikováno v:
Acta Biochimica Polonica. 41:281-292
The gene for thermostable farnesyl diphosphate synthase from Bacillus stearothermophilus was cloned, sequenced, and overexpressed in Escherichia coli. The synthase was purified to homogeneity and crystallized. The enzyme carried only two cysteine res
Publikováno v:
Canadian Journal of Chemistry. 72:75-79
Site-directed mutation was introduced into the gene for the farnesyl diphosphate synthase of Bacillus stearothermophilus. To investigate the significance of the three C-terminal amino acids, where arginine is completely conserved throughout the farne
Autor:
Norifumi Morikawa, Yasuo Takeda, Naoko Fukunaga, Yoshihiro Shimodozono, Keiko Yaji, Kazuro Ikawa, Akari Shigemi, Katsushi Yamada, Ayumi Takeshita, Kazuaki Matsumoto
Publikováno v:
International Journal of Antimicrobial Agents. 33:98-99
Autor:
Kogenta Nakamura, Ayumi Takeshita, Norifumi Morikawa, Yuta Yokoyama, Yasuo Takeda, M. Okuno, Akari Shigemi, Yasuhiro Umezaki, Erika Watanabe, Kazuro Ikawa, Kazuaki Matsumoto
Publikováno v:
International Journal of Antimicrobial Agents. 42:S45
Publikováno v:
Biochemistry. 33(42)
p-(Chloromercuri)benzoic acid inhibited the catalytic activity of Bacillus stearothermophilus farnesyl diphosphate synthase (FPP synthase), which contains only two cysteine residues at positions 73 and 289. In order to explore the role of the cystein