Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ayumi Takakura"'
Autor:
Ayumi Takakura, Toshinori Hirai, Naomi Hamaguchi, Rika Mukohara, Kazutaka Matsumoto, Yutaka Yano, Takuya Iwamoto
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 9, Iss 1, Pp 1-6 (2023)
Abstract Background Our case is the first report showing the development of hypoglycemia following the administration of vadadustat in a patient with chronic kidney disease being treated with mitiglinide and sitagliptin, possibly due to drug–drug i
Externí odkaz:
https://doaj.org/article/b96d630e7f6a4ebc9a7d9bf866ad54fb
Autor:
C. William Wester, Bryan E. Shepherd, Usman J. Wudil, Baba Maiyaki Musa, Donna J. Ingles, Heather L. Prigmore, Faisal S. Dankishiya, Aima A. Ahonkhai, Bukar A. Grema, Philip J. Budge, Ayumi Takakura, Opeyemi A. Olabisi, Cheryl A. Winkler, Jeffrey B. Kopp, Joseph V. Bonventre, Christina M. Wyatt, Muktar H. Aliyu
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Background Microalbuminuria is an independent risk factor for cardiovascular and kidney disease and a predictor of end organ damage, both in the general population and in persons with HIV (PWH). Microalbuminuria is also an important risk fac
Externí odkaz:
https://doaj.org/article/7f7310b716ec4421be479d015ca124c3
Autor:
Amanda J. Clark, Marie Christelle Saade, Vamsidhara Vemireddy, Kyle Q. Vu, Brenda Mendoza Flores, Valerie Etzrodt, Erin J. Ciampa, Huihui Huang, Ayumi Takakura, Kambiz Zandi-Nejad, Zsuzsanna K. Zsengellér, Samir M. Parikh
Nicotinamide adenine dinucleotide (NAD+) levels decline in experimental models of acute kidney injury (AKI). Attenuated enzymatic conversion of tryptophan to NAD+ in tubular epithelium may contribute to adverse cellular and physiological outcomes. Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a498630bd9b4caab45b365ff79965c9
https://doi.org/10.1101/2023.05.23.541987
https://doi.org/10.1101/2023.05.23.541987
Autor:
Ayumi Takakura, Kambiz Zandi-Nejad
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33(6)
Sepsis is characterized by systemic inflammation that is caused by infection and by activation of proinflammatory pathways, resulting in mitochondrial and cellular dysfunction leading to multiorgan failure. Here, we show the following: 1) in peritone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a816f1a1c4498cc04b2c359061a118e3
https://pubmed.ncbi.nlm.nih.gov/30951370
https://pubmed.ncbi.nlm.nih.gov/30951370
Publikováno v:
Gut microbes. 9(1)
The mechanisms underlying the systemic effects mediated by gut microbiota are under active investigation. In addition to local, direct effects of gut microbiota on the host, metabolic products from microbiota may act peripherally, reaching distal org
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd6f04c5badbe72db8af26fd2abd70f
https://pubmed.ncbi.nlm.nih.gov/28961041
https://pubmed.ncbi.nlm.nih.gov/28961041
Autor:
Jing Zhou, Vy Nguyen, Kristina A. Roberts, Markus Plomann, Gang Yao, Ayumi Takakura, Xuefeng Su, Xiaogang Li
Publikováno v:
Human Molecular Genetics. 23:2769-2779
How epithelial cells form a tubule with defined length and lumen diameter remains a fundamental question in cell and developmental biology. Loss of control of tubule lumen size in multiple organs including the kidney, liver and pancreas features poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e03a22a0159151424961cf3c665175
https://doi.org/10.1093/hmg/ddt672
https://doi.org/10.1093/hmg/ddt672
Publikováno v:
Kidney International. 83(3):426-437
The protein kinase C and casein kinase 2 substrate in neurons (Pacsin) is a subfamily of membrane-binding proteins that participates in vesicle trafficking and cytoskeleton organization. Here, we studied Pacsin 2 in kidney development and repair foll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9bd96d42e304535b57982937fd3f57b
Autor:
Marwan Mounayar, Najib El Haddad, Paolo Fiorina, Reza Abdi, Thomas Rückle, Robert Moore, Alessandra Petrelli, Ayumi Takakura, Sunmi Yang, Wassim Elyaman, Mollie Jurewicz, Jamil Azzi
Publikováno v:
Diabetes
Type 1 diabetes (T1D) remains a major health problem worldwide, with a steadily rising incidence yet no cure. Phosphoinositide 3-kinase-γ (PI3Kγ), a member of a family of lipid kinases expressed primarily in leukocytes, has been the subject of subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb19c3cbc09a40d2111932b1cb88d659
https://doi.org/10.2337/db11-0134
https://doi.org/10.2337/db11-0134
Autor:
Shan Qin, Surya M. Nauli, Leah Contrino, Jing Zhou, Mary Taglienti, Jordan A. Kreidberg, Ayumi Takakura
Publikováno v:
Journal of Clinical Investigation. 120:3617-3628
Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited disorder that is caused by mutations at two loci, polycystin 1 (PKD1) and polycystin 2 (PKD2). It is characterized by the formation of multiple cysts in the kidneys that can l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b567703312defe68e88898bd7b0e2d56
https://doi.org/10.1172/jci41531
https://doi.org/10.1172/jci41531
Autor:
Jing Zhou, Sarah Gondela, Annouck Luyten, Ying Chen, Santiago B. Rompani, Ayumi Takakura, Xuefeng Su
Publikováno v:
Journal of the American Society of Nephrology. 21:1521-1532
Mutations in PKD1, which encodes polycystin-1 (PC1), contribute to >85% of cases of autosomal dominant polycystic kidney disease (ADPKD). The planar cell polarity (PCP) pathway is necessary for the oriented cell division and convergent extension that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c4d32e6250bbe31ae1c6708b57ec485
https://doi.org/10.1681/asn.2010010127
https://doi.org/10.1681/asn.2010010127