Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Ayumi Nishimura"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Macrophages contribute to adipose tissue homeostasis; however, they are also thought to be responsible for insulin resistance in obesity. Macrophages, which were oversimplified in past methodologies, have become rather difficult to understand compreh
Externí odkaz:
https://doaj.org/article/9d3039794f634c508880026e71d4f117
Autor:
Yoshiyuki Watanabe, Shiho Fujisaka, Yoshitomo Morinaga, Shiro Watanabe, Allah Nawaz, Hideki Hatta, Tomonobu Kado, Ayumi Nishimura, Muhammad Bilal, Muhammad Rahil Aslam, Keiko Honda, Yoshimi Nakagawa, Samir Softic, Kenichi Hirabayashi, Takashi Nakagawa, Yoshinori Nagai, Kazuyuki Tobe
Publikováno v:
Molecular Metabolism, Vol 77, Iss , Pp 101797- (2023)
Objective: Polyphenols have health-promoting effects, such as improving insulin resistance. Isoxanthohumol (IX), a prenylated flavonoid found in beer hops, has been suggested to reduce obesity and insulin resistance; however, the mechanism remains un
Externí odkaz:
https://doaj.org/article/5e617e1c998c4930b7ab219ec79db80e
Autor:
Allah Nawaz, Muhammad Bilal, Shiho Fujisaka, Tomonobu Kado, Muhammad Rahil Aslam, Saeed Ahmed, Keisuke Okabe, Yoshiko Igarashi, Yoshiyuki Watanabe, Takahide Kuwano, Koichi Tsuneyama, Ayumi Nishimura, Yasuhiro Nishida, Seiji Yamamoto, Masakiyo Sasahara, Johji Imura, Hisashi Mori, Martin M. Matzuk, Fujimi Kudo, Ichiro Manabe, Akiyoshi Uezumi, Takashi Nakagawa, Yumiko Oishi, Kazuyuki Tobe
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Muscle regeneration requires the contribution and communication of various different cell types. Here, Nawaz et al. show that CD206+ macrophages inhibit the secretion of the promyogenic factor follistatin by fibro-adipogenic progenitor cells, impedin
Externí odkaz:
https://doaj.org/article/940fc3d0e8834f71b70e400aa3500e3a
Autor:
Muhammad Bilal, Allah Nawaz, Tomonobu Kado, Muhammad Rahil Aslam, Yoshiko Igarashi, Ayumi Nishimura, Yoshiyuki Watanabe, Takahide Kuwano, Jianhui Liu, Hiroyuki Miwa, Takumi Era, Koichi Ikuta, Johji Imura, Kunimasa Yagi, Takashi Nakagawa, Shiho Fujisaka, Kazuyuki Tobe
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101328- (2021)
Objective: Expansion of adipose tissue during obesity through the recruitment of newly generated adipocytes (hyperplasia) is metabolically healthy, whereas that through the enlargement of pre-existing adipocytes (hypertrophy) leads to metabolic compl
Externí odkaz:
https://doaj.org/article/26f597ca874e42599c41c8fa0a7b32a1
Autor:
Yoshiyuki Watanabe, Shiho Fujisaka, Kazutaka Ikeda, Masaki Ishikawa, Takahiro Yamada, Allah Nawaz, Tomonobu Kado, Takahide Kuwano, Ayumi Nishimura, Muhammad Bilal, Jianhui Liu, Kunimasa Yagi, Koji Hase, Kazuyuki Tobe
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102445- (2021)
Summary: The gut microbiota metabolizes the nutrients to produce various metabolites that play crucial roles in host metabolism. However, the links between the microbiota established by different nutrients and the microbiota-influenced changes in the
Externí odkaz:
https://doaj.org/article/13352c328d3c4ccab6b6ae019109e49d
Autor:
Takahide Kuwano, Hironori Izumi, Muhammad Rahil Aslam, Yoshiko Igarashi, Muhammad Bilal, Ayumi Nishimura, Yoshiyuki Watanabe, Allah Nawaz, Tomonobu Kado, Koichi Ikuta, Seiji Yamamoto, Masakiyo Sasahara, Shiho Fujisaka, Kunimasa Yagi, Hisashi Mori, Kazuyuki Tobe
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248267 (2021)
Meflin (Islr) expression has gained attention as a marker for mesenchymal stem cells, but its function remains largely unexplored. Here, we report the generation of Meflin-CreERT2 mice with CreERT2 inserted under the Meflin gene promoter to label Mef
Externí odkaz:
https://doaj.org/article/21c085d407024df5a22ce3b5bee77b7b
Autor:
Allah Nawaz, Yasuhiro Nishida, Akiko Takikawa, Shiho Fujisaka, Tomonobu Kado, Aminuddin Aminuddin, Muhammad Bilal, Ishtiaq Jeelani, Muhammad Rahil Aslam, Ayumi Nishimura, Takahide Kuwano, Yoshiyuki Watanabe, Yoshiko Igarashi, Keisuke Okabe, Saeed Ahmed, Azhar Manzoor, Isao Usui, Kunimasa Yagi, Takashi Nakagawa, Kazuyuki Tobe
Publikováno v:
Nutrients, Vol 13, Iss 12, p 4374 (2021)
Recently, obesity-induced insulin resistance, type 2 diabetes, and cardiovascular disease have become major social problems. We have previously shown that Astaxanthin (AX), which is a natural antioxidant, significantly ameliorates obesity-induced glu
Externí odkaz:
https://doaj.org/article/8b8b9d9582ae4559bc4d5e3b158419ee
Autor:
null Ana Luiza Esteves Carneiro, null Danielle Ayumi Nishimura, null Romualdo Monteiro de Barros, null Henrique Tuzzolo-Neto, null Jun Ho Kim, null Claudio Costa
Publikováno v:
RSBO. 18:221-05
The aim of the present study was to analyze cone-beam computed tomography (CBCT) images to study the prevalence of foramen of Huschke (FH) and petrotympanic fissure (PF) in a sample of the Brazilian population. Material and Methods: A total of 146 CB
Autor:
Arthur Rodriguez Gonzalez Cortes, Christyan Hiroshi Iida, Danielle Ayumi Nishimura, Ana Luiza Esteves Carneiro, Claudio Costa, Emiko Saita Arita
Publikováno v:
Journal of Oral Implantology. 47:159-167
Autor:
Allah, Nawaz, Muhammad, Bilal, Shiho, Fujisaka, Tomonobu, Kado, Muhammad Rahil, Aslam, Saeed, Ahmed, Keisuke, Okabe, Yoshiko, Igarashi, Yoshiyuki, Watanabe, Takahide, Kuwano, Koichi, Tsuneyama, Ayumi, Nishimura, Yasuhiro, Nishida, Seiji, Yamamoto, Masakiyo, Sasahara, Johji, Imura, Hisashi, Mori, Martin M, Matzuk, Fujimi, Kudo, Ichiro, Manabe, Akiyoshi, Uezumi, Takashi, Nakagawa, Yumiko, Oishi, Kazuyuki, Tobe
Publikováno v:
Nature communications. 13(1)
Muscle regeneration requires the coordination of muscle stem cells, mesenchymal fibro-adipogenic progenitors (FAPs), and macrophages. How macrophages regulate the paracrine secretion of FAPs during the recovery process remains elusive. Herein, we sys