Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ayumi Kuga"'
Autor:
Masayuki Yamamoto, Hozumi Motohashi, Hiroshi Kitamura, Harit Panda, Mikiko Suzuki, Ayumi Kuga, Makiko Hayashi
The transcription factor Nrf2 activates transcription of cytoprotective genes during oxidative and electrophilic insults. Nrf2 activity is regulated by Keap1 in a stress-dependent manner in normal cells, and somatic loss-of-function mutations of Keap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b3c331a31ed3b4534501fd3df6d6d13
https://doi.org/10.1158/0008-5472.c.6511550
https://doi.org/10.1158/0008-5472.c.6511550
Autor:
Masayuki Yamamoto, Hozumi Motohashi, Hiroshi Kitamura, Harit Panda, Mikiko Suzuki, Ayumi Kuga, Makiko Hayashi
Figure S1: Expression of Keap1 and Nqo1 in Keap1WT/WT, Keap1FB/FB and Keap1FA/FA mouse tissues; Figure S2: Analyses of tumor-bearing mouse cohorts; Figure S3: Origins of tumor cells in Kras::Keap1WT/WT, Kras::Keap1FB/FB and Kras::Keap1FA/FA lungs; Fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f6d466eb695b074797c9e304f239ad
https://doi.org/10.1158/0008-5472.22423673
https://doi.org/10.1158/0008-5472.22423673
Autor:
Ayumi Kuga, Kouhei Tsuchida, Harit Panda, Makoto Horiuchi, Akihito Otsuki, Keiko Taguchi, Fumiki Katsuoka, Mikiko Suzuki, Masayuki Yamamoto
Publikováno v:
Mol Cell Biol
Nrf2 activates cytoprotective gene expression, and Nrf2 activity is regulated through at least two protein degradation pathways: the Keap1-mediated and β-TrCP-mediated pathways. To address the relative contributions of these pathways, we generated k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e20afe1b5dbcd4ce6b76c72e426517d6
https://europepmc.org/articles/PMC9302178/
https://europepmc.org/articles/PMC9302178/
Autor:
Ayumi Kuga, Mikiko Suzuki, Hiroshi Kitamura, Masayuki Yamamoto, Makiko Hayashi, Harit Panda, Hozumi Motohashi
Publikováno v:
Cancer research. 80(16)
The transcription factor Nrf2 activates transcription of cytoprotective genes during oxidative and electrophilic insults. Nrf2 activity is regulated by Keap1 in a stress-dependent manner in normal cells, and somatic loss-of-function mutations of Keap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f35bd2a629298a073e9f3d15dd2152
https://pubmed.ncbi.nlm.nih.gov/32636316
https://pubmed.ncbi.nlm.nih.gov/32636316
Autor:
Ayumi Kuga, Nobuo Fuke, Mikiko Suzuki, Nadine Keleku-Lukwete, Hiroyuki Suganuma, Masayuki Yamamoto, Harit Panda
Publikováno v:
Experimental hematology. 77
Sickle cell disease (SCD) is a recessively inherited blood disorder caused by abnormal β-globin production. The β-globin mutation changes erythrocyte morphology into a sickle shape and increases erythrocyte vulnerability to hemolysis. Oxidative str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e4671870875868d33c16777222051c6
https://pubmed.ncbi.nlm.nih.gov/31404577
https://pubmed.ncbi.nlm.nih.gov/31404577