Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ayumi Asaeda"'
Autor:
Kenjiro Asagoshi, Hiroshi Ide, Satoshi Matsuyama, Ayumi Asaeda, Yasuhiko Takamori, Keizo Tano, Akira Murakami, Kihei Kubo
Publikováno v:
Biochemistry. 39:1959-1965
The activity of human methylpurine DNA N-glycosylase (hMPG) for major substrates was directly compared using two types of substrates, i.e., natural DNA and synthetic oligonucleotides. By the use of ARP assay detecting abasic sites in DNA, we first in
Publikováno v:
Analytica Chimica Acta. 365:35-41
We have recently developed a novel method for detection and quantitation of abasic (AP) sites in DNA, in which the biotinylated reagent, called the aldehyde reactive probe (ARP) specifically reacts with aldehyde groups of AP sites and biotin-tagged d
Autor:
Fumihito Ohashi, Akiko Shiomi, Yasuhiko Takamori, Kihei Kubo, Hiroshi Ide, Ayumi Asaeda, Satoshi Matsuyama
Publikováno v:
Journal of Veterinary Medical Science. 60:1293-1297
Fluorodeoxyuridine, an inhibitor of thymidylate synthetase, is known to induce chromosomal fragile sites. The drug treatment may cause deprivation of intracellular thymidine nucleotide pool followed by a serious imbalance of deoxynucleotide pool. Tho
Autor:
Ayumi Asaeda, Kazuaki Yamashita, Mitsuru Yanai, Yasushi Shirahase, Yasuhiro Sakai, Kazunari Kumasaka, Kouji Sakaguchi, Theo Wallimann, Uwe Schlattner, Tadashi Hoshino, Kouji Kishi
Publikováno v:
Scandinavian Journal of Clinical and Laboratory Investigation
Scandinavian Journal of Clinical and Laboratory Investigation, Taylor & Francis, 2009, pp.1-9. ⟨10.1080/00365510902981171⟩
Scandinavian Journal of Clinical and Laboratory Investigation, Taylor & Francis, 2009, pp.1-9. ⟨10.1080/00365510902981171⟩
International audience; Objective: The MB fraction of creatine kinase (CK-MB) has long been used as a cardiac marker. It is known that the CK-MB immunoinhibition method lacks selectivity and accuracy, because the appearance of macro CK type 2, corres
Publikováno v:
Nucleosidesnucleotides. 17(1-3)
Human methylpurine N-glycosylase (MPG) activity was investigated by monitoring abasic (AP) sites resulting from removal of alkylated bases. The amount of AP sites in MMS-treated HeLa cells transiently increased at 3 h, then gradually decreased to 40%
Autor:
Satoshi Nakajima, Kazuo Yamamoto, Kihei Kubo, Yusuke Saito, Ayumi Asaeda, Keiichi Ono, Fumiko Uraki
The nth and nei genes of Escherichia coli affect the production of endonuclease III and endonuclease VIII, respectively, glycosylases/apurinic lyases that attack DNA damaged by oxidizing agents. Here, we provide evidence that oxidative lethal lesions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aba6a71b78bde8181753358fd47b0db1
https://europepmc.org/articles/PMC179178/
https://europepmc.org/articles/PMC179178/
Autor:
Hiroshi Ide, Yasuhiko Takamori, Yoshiharu Kimura, Keisuke Makino, Kenji Michiue, Ayumi Asaeda, Kihei Kubo, Ken Akamatsu
Publikováno v:
Biochemistry. 32(32)
The abasic site (apurinic/apyrimidinic site) is the most common lesion in DNA and is suggested to be an important intermediate in mutagenesis and carcinogenesis. We have recently reported a novel assay for the detection and quantitation of abasic sit