Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Aysun Adan"'
Publikováno v:
PeerJ, Vol 8, p e9369 (2020)
MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression found in more than 200 diverse organisms. Although it is still not fully established if RNA viruses could generate miRNAs, there are examples of miRNA like sequences from RNA v
Externí odkaz:
https://doaj.org/article/8fa0cd36b97b451a8615af1f1886e893
Autor:
Nur Şebnem Ersöz, Aysun Adan
Publikováno v:
Proceedings, Vol 40, Iss 1, p 4 (2019)
Sphingolipids are important signaling lipids which play crucial roles to determine the cell fate. Ceramide, apoptotic central molecule of sphingolipid metabolism, which is produced through de novo pathway by serine palmitoyl transferase (SPT) and can
Externí odkaz:
https://doaj.org/article/ae265e3c33634eb0af04f9b38f85647b
Autor:
Osman Oğuz, Aysun Adan
Publikováno v:
Proceedings, Vol 40, Iss 1, p 3 (2019)
The mechanisms underlying the growth inhibitory effect of resveratrol on Ph+ ALL cells were investigated with regard to targeting of ceramide metabolism and changes in BCR-ABL expression. Growth inhibition and apoptotic effects of resveratrol, SK inh
Externí odkaz:
https://doaj.org/article/c28c75f64298462e927f07a942a2e181
Publikováno v:
Turkish Journal of Hematology, Vol 32, Iss 2, Pp 118-126 (2015)
INTRODUCTION: The aims of this study were to examine the cytotoxic and apoptotic effects of KL-21, a novel plant product (produced by Naturin Natural Products, İzmir, Turkey), on 232B4 chronic lymphocytic leukemia (CLL) cells and to determine the cy
Externí odkaz:
https://doaj.org/article/1abc846eaad04a9591c1471a49f10b8a
Autor:
Osman Oğuz, Aysun Adan
Publikováno v:
Proceedings, Vol 1, Iss 10, p 984 (2017)
Bioactive sphingolipids are a lipid family including ceramide, sphingosine-1-phosphate (S1P) and glucosyl ceramide (GC). Ceramide produced through de novo synthesis pathway (Serine Palmitoyl Transferase (SPT) is a key enzyme subjected to regulation)
Externí odkaz:
https://doaj.org/article/514816f443b64f2aa8d439e3506cfeba
Autor:
Aysun Adan, Melisa Tecik
Publikováno v:
OncoTargets and Therapy. 15:1449-1478
FMS-like tyrosine kinase 3 (FLT3) is mutated in approximately 30% of acute myeloid leukemia (AML) patients. The presence of FLT3-ITD (internal tandem duplication, 20-25%) mutation and, to a lesser extent, FLT3-TKD (tyrosine kinase domain, 5-10%) muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af637bb2420611859598cf8220bf1a0
https://doi.org/10.2147/ott.s384293
https://doi.org/10.2147/ott.s384293
Autor:
Aysun Adan, NUR ŞEBNEM ERSÖZ
Publikováno v:
Cytotechnology
© 2022, The Author(s), under exclusive licence to Springer Nature B.V.Treatment of FMS-like tyrosine kinase 3 (FLT3)-internal tandem duplication (ITD) AML is restricted due to toxicity, drug resistance and relapse eventhough targeted therapies are c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3618f8338677ede529adf64f661f89
https://doi.org/10.1007/s10616-022-00527-1
https://doi.org/10.1007/s10616-022-00527-1
Autor:
Hande Nur Şahin, Aysun Adan
Publikováno v:
Turkish Journal of Biochemistry. 47:49-58
Objectives Therapeutic potential of clinically approved FLT3 inhibitor midostaurin has been neglected in wild-type FLT3 positive acute myeloid leukemia (AML). Sphingosine kinase-1 (SK-1) having anti-proliferative functions is studied in various cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac19a08b1ecf699e7fa997c535773d0
https://doi.org/10.1515/tjb-2021-0152
https://doi.org/10.1515/tjb-2021-0152
Autor:
Hande Şahin, Aysun Adan
Publikováno v:
Experimed. 11:149-155
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9eb980763175e4f3171d31c10984bb81
https://doi.org/10.26650/experimed.2021.974943
https://doi.org/10.26650/experimed.2021.974943
Publikováno v:
In Food Hydrocolloids May 2014 36:130-142