Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Aysu Uygur"'
Publikováno v:
Developmental cell
SUMMARY Anatomical proportions are robustly maintained in individuals that vary enormously in size, both within a species and between members of related taxa. However, the mechanisms underlying scaling are still poorly understood. We have examined th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee0550e772045f033fa857893b092b84
Autor:
Norma P. Gerard, Juan Manuel González-Rosa, Niranjana Natarajan, Lucas H. Cocco-Delgado, Michka Sharpe, Calum A. MacRae, Nhi Ngoc Ho, Jessica L. Whited, Aysu Uygur, Craig Gerard, Caroline E. Burns, Richard T. Lee, Donald M. Bryant, C. Geoffrey Burns, Yamen Abbas
Background: Defining conserved molecular pathways in animal models of successful cardiac regeneration could yield insight into why adult mammals have inadequate cardiac regeneration after injury. Insight into the transcriptomic landscape of early car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60cb6ef7050ede78259f1cfee645a4cb
https://europepmc.org/articles/PMC5953786/
https://europepmc.org/articles/PMC5953786/
Autor:
Wanda Setlik, Deborah L. Gumucio, Karan Nagar, James G. Fox, Meenakshi Rao, Jean Phillipe Pradere, Michael Churchill, Yagnesh Tailor, Simon Renders, Sureshkumar Muthupalani, Heon Goo Lee, Nicholas A. Manieri, Mark Glaire, Andrew S. Giraud, Siddhartha Mukherjee, Tracy C. Grikscheit, Stefanie Gross, Richard A. Friedman, Bernhard W. Renz, Francis Y. Lee, Maximilian Reichert, Anil K. Rustgi, Daniel L. Worthley, Yoku Hayakawa, Yiling Si, Aysu Uygur, Abhinav Nair, Jared Carpenter, Samuel Asfaha, Ashley N. Martinez, Xiaowei Chen, Hongshan Wang, Peter A. Sims, Ajay Prakash, Mazen A. Kheirbek, Gerard Karsenty, Jon Michael Caldwell, Katherine D. Walton, Robert F. Schwabe, Alka Kolhe, Trevor A. Graham, Michael D. Gershon, Jocelyn T. Compton, Saqib Nizami, H. Paco Kang, Matthew G. Schwartz, Guangchun Jin, Timothy C. Wang, Daniel E. Levin, C. Benedikt Westphalen, Thaddeus S. Stappenbeck
Publikováno v:
Cell, vol 160, iss 1-2
PMC
Paediatrics Publications
PMC
Paediatrics Publications
The stem cells that maintain and repair the postnatal skeleton remain undefined. One model suggests that perisinusoidal mesenchymal stem cells (MSCs) give rise to osteoblasts, chondrocytes, marrow stromal cells, and adipocytes, although the existence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0584b21d4cc6a0c685bd69e8d2f5e0
Autor:
Margaret M. Brosnahan, Aysu Uygur, Kimberly L. Cooper, Karen E. Sears, D. F. Antczak, Jennifer A. Maier, Julian A. Skidmore, Karl Stephan Baczkowski, Clifford J. Tabin
Publikováno v:
Nature. 511:41-45
A reduction in the number of digits has evolved many times in tetrapods, particularly in cursorial mammals that travel over deserts and plains, yet the underlying developmental mechanisms have remained elusive. Here we show that digit loss can occur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8069036eeb2b36c5aaedc2fb957e137a
https://doi.org/10.1038/nature13496
https://doi.org/10.1038/nature13496
Autor:
Jill M. Goldstein, Emilia Gonzalez, Miook Cho, Tommaso Poggioli, Aysu Uygur, Amy J. Wagers, Claudio Macias-Trevino, Francesco S. Loffredo, Ryan G. Walker, Rachel M Tandias, Peiguo Yang, Ana Vujic, Richard T. Lee, James R. Pancoast, Yick W. Fong, Thomas B. Thompson
Publikováno v:
Circulation research. 118(1)
Rationale: Growth differentiation factor 11 (GDF11) and GDF8 are members of the transforming growth factor-β superfamily sharing 89% protein sequence homology. We have previously shown that circulating GDF11 levels decrease with age in mice. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7edfa0401f67c7542b1bd11833cbded
https://pubmed.ncbi.nlm.nih.gov/29301851
https://pubmed.ncbi.nlm.nih.gov/29301851
Publikováno v:
The FASEB Journal. 28
Since the origin of tetrapod limbs about 450 million years ago, every Class of land vertebrate - reptiles, birds, amphibians, and mammals - has undergone some degree of digit loss from the ancestral count of five. Even within mammals many species hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29e3ff500f7cda70de95c70e8bba3a35
https://doi.org/10.1096/fasebj.28.1_supplement.919.6
https://doi.org/10.1096/fasebj.28.1_supplement.919.6