Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ayslan Castro Brant"'
Autor:
Bruna Palma Matta, Renan Gomes, Daniel Mattos, Renata Olicio, Caroline Macedo Nascimento, Gerson Moura Ferreira, Ayslan Castro Brant, Mariana Boroni, Carolina Furtado, Valdirene Lima, Miguel Ângelo Martins Moreira, Anna Cláudia Evangelista dos Santos
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Several studies have demonstrated the cost-effectiveness of genetic testing for surveillance and treatment of carriers of germline pathogenic variants associated with hereditary breast/ovarian cancer syndrome (HBOC). In Brazil, seventy perce
Externí odkaz:
https://doaj.org/article/00f066d23c3340e78d0de67740044707
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract SARS-CoV-2 is an extremely contagious respiratory virus causing adult atypical pneumonia COVID-19 with severe acute respiratory syndrome (SARS). SARS-CoV-2 has a single-stranded, positive-sense RNA (+RNA) genome of ~ 29.9 kb and exhibits sig
Externí odkaz:
https://doaj.org/article/6f21d2470277432492938faef517d6ae
Autor:
Albert N. Menezes, Liz Maria de Almeida, Shayany Pinto Felix, Miguel A. M. Moreira, Ayslan Castro Brant
Publikováno v:
Genomics. 112:2942-2948
Multiple infections by HPV genotypes are frequently detected in HPV+ cervical lesions but the interaction between each viral genotype during carcinogenesis is poorly understood. Here we carried out a comprehensive study to characterize the multiple H
Publikováno v:
Cell & Bioscience
Cell & Bioscience, Vol 11, Iss 1, Pp 1-17 (2021)
Cell & Bioscience, Vol 11, Iss 1, Pp 1-17 (2021)
SARS-CoV-2 is an extremely contagious respiratory virus causing adult atypical pneumonia COVID-19 with severe acute respiratory syndrome (SARS). SARS-CoV-2 has a single-stranded, positive-sense RNA (+RNA) genome of ~ 29.9 kb and exhibits significant
Autor:
Marcelo A. Soares, Albert N. Menezes, Miguel de Mulder Rougvie, Miguel Ângelo M. Moreira, Ayslan Castro Brant, Gislaine Curty
Publikováno v:
Cancers
Volume 13
Issue 14
Cancers, Vol 13, Iss 3513, p 3513 (2021)
Volume 13
Issue 14
Cancers, Vol 13, Iss 3513, p 3513 (2021)
Simple Summary Retroelements are endogenous DNA elements present in the human genome. They have a key role in tumorigenesis and cancer progression. Several studies have reported their expression as biomarkers and immunotherapeutic targets to cancer.
Autor:
Evandro Lucena, Maria Carolina Viana, Hector N. Seuanez, Vanessa Mendonça, William Corrêa Tavares, Mariana Boroniv, Ayslan Castro Brant
Publikováno v:
World Journal of Veterinary Research. 1:05-10
The tumor suppressor, Human Retinoblastoma Susceptibility Gene (RB1) plays a prominent role in normal development, gene transcription, DNA replication, repair, and mitosis, and its complete biallelic dysfunction in retinoblasts is the main cause of r
Publikováno v:
Virologica Sinica
Human papillomavirus 18 (HPV18) E6 and E7 oncogenes are transcribed as a single bicistronic E6E7 pre-mRNA. The E6 ORF region in the bicistronic E6E7 pre-mRNA contains an intron. Splicing of this intron disrupts the E6 ORF integrity and produces a spl
Autor:
Anna Cláudia Evangelista dos Santos, Renan Gomes, Caroline Macedo Nascimento, Silvia Maria de Aquino Paes, Pricila da Silva Spinola, Bruna Palma Matta, Miguel A. M. Moreira, Ayslan Castro Brant, Cibele R. Bonvicino
Publikováno v:
Breast cancer research and treatment. 185(3)
This study aimed to identify and classify genetic variants in consensus moderate-to-high-risk predisposition genes associated with Hereditary Breast and Ovarian Cancer Syndrome (HBOC), in BRCA1/2-negative patients from Brazil. The study comprised 126
Autor:
Luís Felipe Leite Martins, João Paulo C. B. Vidal, Liz Maria de Almeida, Fernanda Nahoum Carestiato, Sérgio Menezes Amaro Filho, Silvia Maria Baeta Cavalcanti, Neilane Bertoni, Miguel A. M. Moreira, Ayslan Castro Brant, Shayany Pinto Felix
Publikováno v:
Virus Research. 232:48-53
CpG methylation at early promoter of HPV16 DNA, in the 3' end of the Long Control Region (3'LCR), has been associated to the presence of episomal forms of viral genome and, consequently, intact E1 and E2 ORFs. The DNA methylation would block the acce
Autor:
Michael Sammeth, Miguel A. M. Moreira, Liz Maria de Almeida, Ayslan Castro Brant, Albert N. Menezes, Shayany Pinto Felix
Publikováno v:
Genomics. 111(6)
Scarce data are available on the expression of papillomavirus genome and the frequency of alternatively spliced E6E7 mRNAs in invasive cervical cancer. We carried out a comprehensive characterization of HPV expression by RNA-Seq analysis in 22 invasi