Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Aysha B. Khalid"'
Publikováno v:
Cogent Engineering, Vol 2, Iss 1 (2015)
Cnr2 is one of two cannabinoid receptors known to regulate bone metabolism. Here, we compared the whole bone properties of femora and tibiae from three-month-old Cnr2−/- mice with wild-type controls using a C57BL/6 background. Bending stiffness was
Externí odkaz:
https://doaj.org/article/9edd1e5cc8f645a4a64b2844be392b6e
Autor:
Susan A. Krum, Gustavo A. Miranda-Carboni, Tiffany N. Seagroves, Alexandria V. Slayden, Jerusha Kumpati, Aysha B. Khalid, Iram Fatima, Ikbale El Ayachi, Jesus Garcia-Lopez, Maria Angeles Lillo Osuna
Osteosarcoma is a malignant tumor in the bone, which originates from normal osteoblasts or osteoblast precursors. Normal osteoblasts express estrogen receptor alpha (ERα); however, osteosarcomas do not express ERα due to promoter DNA methylation. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34647a5808ecd8a7f5c59539bfd05419
https://doi.org/10.1158/0008-5472.c.6511551.v1
https://doi.org/10.1158/0008-5472.c.6511551.v1
Autor:
Susan A. Krum, Gustavo A. Miranda-Carboni, Tiffany N. Seagroves, Alexandria V. Slayden, Jerusha Kumpati, Aysha B. Khalid, Iram Fatima, Ikbale El Ayachi, Jesus Garcia-Lopez, Maria Angeles Lillo Osuna
Supplementary Figure 1. Media and serum effect on 143B cells. Supplementary Figure 2. Publicly available osteosarcoma data. Supplementary Figure 3. Effects of DAC on U2OS cells. Supplementary Figure 4. Effects of DAC on MG63 cells. Supplementary Figu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a317a9466cf88a01fb3e5a6621f90a7
https://doi.org/10.1158/0008-5472.22423674.v1
https://doi.org/10.1158/0008-5472.22423674.v1
Autor:
Anas M. Khanshour, Yongbo Lu, Xudong Xie, Stephen Aplin Lyon, Jamie Russell, Bruce Beutler, Eva Marie Y. Moresco, Aysha B. Khalid, Yang Li, Nandina Paria, Qian Xu, Jian Q. Feng, Joshua E. Mayfield, Kristin Denton, Xiaohong Li, Julia Kozlitina, Robert E. Hammer, Sara Ludwig, Jonathan J. Rios, Amy F Lewanda, Carol Wise, Carlos Ferreira, Miao Tang
Publikováno v:
J Bone Miner Res
Proper embryonic and postnatal skeletal development require coordination of myriad complex molecular mechanisms. Disruption of these processes, through genetic mutation, contributes to variation in skeletal development. We developed a high-throughput
Autor:
Jerusha Kumpati, Aysha B. Khalid, Jesus Garcia-Lopez, Tiffany N. Seagroves, Ikbale El Ayachi, Susan A. Krum, Maria Angeles Lillo Osuna, Iram Fatima, Gustavo A. Miranda-Carboni, Alexandria V. Slayden
Publikováno v:
Cancer Research. 79:1054-1068
Osteosarcoma is a malignant tumor in the bone, which originates from normal osteoblasts or osteoblast precursors. Normal osteoblasts express estrogen receptor alpha (ERα); however, osteosarcomas do not express ERα due to promoter DNA methylation. H
Autor:
Jonathan J. Rios, Carlos Ferreira, Stephen Aplin Lyon, Robert E. Hammer, Amy F Lewanda, Sara Ludwig, Jian Q. Feng, Julia Kozlitina, Anas M. Khanshour, Joshua E. Mayfield, Bruce Beutler, Yang Li, Yongbo Lu, Aysha B. Khalid, Kristin Denton, Xiaohong Li, Qian Xu, Xudong Xie, Carol Wise, Nandina Paria, Miao Tang, Eva Marie Y Moresco, Jamie Russell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff410a54d9f2df68bc9d204dc324329
https://doi.org/10.1002/jbmr.4323/v2/response1
https://doi.org/10.1002/jbmr.4323/v2/response1
Autor:
Yared H. Kidane, F. Kent Hamra, Alexandra J Rafipay, Jacqueline T. Hecht, Mitchell K. Weston, Jonathan J. Rios, Matthew B. Dobbs, B. Stephens Richards, Nandina Paria, Anas M. Khanshour, Megan J. Wilson, Vanessa De Mello, Aysha B. Khalid, Julia Kozlitina, Neil Vargesson, Christina A. Gurnett, Carol Wise, Reuel Cornelia
Publikováno v:
Hum Mol Genet
Talipes equinovarus (clubfoot, TEV) is a congenital rotational foot deformity occurring in 1 per 1000 births with increased prevalence in males compared with females. The genetic etiology of isolated clubfoot (iTEV) remains unclear. Using a genome-wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b6ad8a6eb81a1ad80e7c555814e2d9
https://europepmc.org/articles/PMC7823076/
https://europepmc.org/articles/PMC7823076/
Autor:
Aysha B. Khalid, Sarocha Suthon, Jacquelyn C. Pence, Gustavo A. Miranda-Carboni, Jianjian Lin, Susan A. Krum
Publikováno v:
Bone
GATA4 is a transcription factor that regulates osteoblast differentiation. However, GATA4 is expressed at a higher level in mesenchymal stem cells (MSCs) than in osteoblasts. Therefore, the role of GATA4 in limb bud mesenchyme differentiation was inv
Autor:
Michael D. West, Hal Sternberg, Nyam Osor Chimge, Sara H Windahl, Yonatan Amzaleg, Anna E. Törnqvist, Aysha B. Khalid, Susan A. Krum, Jie Ji, Dustin E. Schones, Donlaporn Kittivanichkul, John A. Katzenellenbogen, Yankel Gabet, Baruch Frenkel, Claes Ohlsson, Elias Sabag
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 183:10-17
Estrogens attenuate bone turnover by inhibiting both osteoclasts and osteoblasts, in part through antagonizing Runx2. Apparently conflicting, stimulatory effects in osteoblast lineage cells, however, sway the balance between bone resorption and bone
Autor:
Ruth O'Regan, Susan A. Krum, Aysha B. Khalid, Victoria L. Seewaldt, William L. Kuenzinger, Lauren Brakefield, Ikbale El-Ayachi, Jackelyn A. Alva-Ornelas, Jackelyn C. Pence, Hilaire C. Playa, Gustavo A. Miranda-Carboni, Peter Wend, Tiffany N. Seagroves, Daniel L. Johnson, Iram Fatima, Raisa I. Krutilina
Publikováno v:
Cancers
Volume 11
Issue 12
Volume 11
Issue 12
Triple-negative breast cancers (TNBCs), which lack specific targeted therapy options, evolve into highly chemo-resistant tumors that metastasize to multiple organs simultaneously. We have previously shown that TNBCs maintain an activated WNT10B-drive