Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Aysen E, Ozel"'
Publikováno v:
Medicine in Drug Discovery, Vol 7, Iss , Pp 100012- (2020)
A coumarin-benzothiazole hybrid 3 was recently reported as a potential anticancer lead compound based on antioxidant and α-glucosidase inhibitory activities. Herein, we report anticancer activity of the lead compound 3 at a single dose (10 μM) agai
Externí odkaz:
https://doaj.org/article/962e14f9732347a48ba643a3454e384e
Publikováno v:
Molecular Crystals and Liquid Crystals. 753:27-49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c29c3941c45cf96642a5d8768e20b6fb
https://doi.org/10.1080/15421406.2022.2084240
https://doi.org/10.1080/15421406.2022.2084240
Publikováno v:
Advances in Chemical and Materials Engineering ISBN: 9781668460092
Polymers are macromolecules with a very high molecular weight that are formed as a result of one or more small molecules bonding to each other, typically by covalent bonds. The concept of macromolecules consisting of many repeating units are publishe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81ee4e27b98be49245a15e69eeb2243c
https://doi.org/10.4018/978-1-6684-6009-2.ch010
https://doi.org/10.4018/978-1-6684-6009-2.ch010
Autor:
Yasemin Budama-Kilinc, Rabia Cakir-Koc, Serda Kecel-Gunduz, Yagmur Kokcu, Bilge Bicak, Hande Mutlu, Aysen E. Ozel
Publikováno v:
PeerJ, Vol 6, p e4270 (2018)
Background N-acetylcarnosine (NAC), a dipeptide with powerful antioxidant properties that is extensively used as a pharmaceutical prodrug for the treatment of cataract and acute gastric disease, was investigated by molecular dynamics with the GROMACS
Externí odkaz:
https://doaj.org/article/86c8ece2e64040a3bdae763c5b35bc56
Publikováno v:
Volume: 26, Issue: 3 135-142
Yüzüncü Yıl Üniversitesi Fen Bilimleri Enstitüsü Dergisi
Yüzüncü Yıl Üniversitesi Fen Bilimleri Enstitüsü Dergisi
Cyclo(Phe-Phe) dipeptidi Alzheimer hastalığı tedavisinde etkili bir dipeptitdir. Bu çalışmada Cyclo(Phe-Phe) dipeptidinin 3-Boyutlu yapısı teorik konformasyon analizi (TKA) metodu ile belirlenmiştir. Konformasyon analizinde, Ramachandran har
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c58d8182a0416ed13ac2a04fd458f7c2
https://doi.org/10.53433/yyufbed.941445
https://doi.org/10.53433/yyufbed.941445
Publikováno v:
Biologically Active Small Molecules ISBN: 9781003283119
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e09cf0087ee3c53abcce2eeaaca778ad
https://doi.org/10.1201/9781003283119-5
https://doi.org/10.1201/9781003283119-5
Publikováno v:
Yüzüncü Yıl Üniversitesi Fen Bilimleri Enstitüsü Dergisi. 26:80-87
Antimikrobiyal ve antikanser gibi önemli biyolojik aktivitelere sahip olan Cyclo(Trp-Trp) dipeptidinin (C₂₂H₂₀N₄O₂) en düşük enerjili moleküler geometrisi, teorik konformasyon analizi hesabını takiben yapılan Yoğunluk Fonksiyonel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fc7ff461704cdead7b8ad9651339a64
https://doi.org/10.53433/yyufbed.908710
https://doi.org/10.53433/yyufbed.908710
Publikováno v:
Volume: 25, Issue: 2 401-409
Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi
Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi
Bu çalışmada HT-29, Hela ve MCF-7 hücre hatlarına karşı antikanser etki gösteren Cyclo(Tyr-Tyr) dipeptidinin olası en kararlı yedi konformasyonu tirozin aminoasilerinin χ yan zincir dihedral açılarına bağlı olarak konformasyon analizi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a0778e49229600f96c81ca04ff81cf4
https://doi.org/10.19113/sdufenbed.881399
https://doi.org/10.19113/sdufenbed.881399
Publikováno v:
Bulletin of the Chemical Society of Ethiopia. 34:613-623
In this study conformation analysis of seven drugs commonly used in the treatment of COVID-19 was performed. The most stable conformers of the drug molecules were used as initial data for docking analysis. Using the Cavityplus program, the probable m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85cb40488acdfee1333839ce68f768b6
https://doi.org/10.4314/bcse.v34i3.16
https://doi.org/10.4314/bcse.v34i3.16
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 40:660-672
The theoretically possible most stable conformation of the cyclic dipeptide, which has a significant anticancer activity, was examined by conformational analysis method and then by DFT calculations. With DFT calculations, cyclo(Ala-His) dipeptide was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94af0da5c5875cfccba11fa1f3ecb6f7
https://doi.org/10.1080/07391102.2020.1817150
https://doi.org/10.1080/07391102.2020.1817150