Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Aysegul Kaymak"'
Autor:
Gokselin Ozgen, Merve Turk Gezer, Guliz Armagan, Petek Ballar Kirmizibayrak, Ayfer Yalcin, Ozgen Ozer, Banu Ozkirim Arslan, Gonul Kayar, Udaya Kumar Dude, Aysegul Kaymak Ozdemir
Publikováno v:
ACS Omega, Vol 9, Iss 16, Pp 18366-18374 (2024)
Externí odkaz:
https://doaj.org/article/03a6f904365a4f3f8e2bab07dd9c9034
Autor:
Ozge Saatci, Aysegul Kaymak, Umar Raza, Pelin G. Ersan, Ozge Akbulut, Carolyn E. Banister, Vitali Sikirzhytski, Unal Metin Tokat, Gamze Aykut, Suhail A. Ansari, Hayriye Tatli Dogan, Mehmet Dogan, Pouria Jandaghi, Aynur Isik, Fatma Gundogdu, Kemal Kosemehmetoglu, Omer Dizdar, Sercan Aksoy, Aytekin Akyol, Aysegul Uner, Phillip J. Buckhaults, Yasser Riazalhosseini, Ozgur Sahin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
The development of chemoresistance is a major hurdle in triple negative breast cancer (TNBC). Here, the authors show that lysyl oxidase (LOX) is overexpressed in chemoresistant TNBCs, and when inhibited reduces collagen cross-linking, fibronectin fib
Externí odkaz:
https://doaj.org/article/f292a5a9fd8f4954a8c5c7cfe015c25d
Akademický článek
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Akademický článek
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Autor:
Pelin Gülizar Ersan, Fatma Gundogdu, Aysegul Uner, Vitali Sikirzhytski, Unal Metin Tokat, Aysegul Kaymak, Phillip Buckhaults, Hayriye Tatlı Doğan, Gamze Aykut, Carolyn E. Banister, Kemal Kosemehmetoglu, Omer Dizdar, Suhail A. Ansari, Umar Raza, Mehmet Dogan, Ozge Saatci, Ozgur Sahin, Aynur Isik, Ozge Akbulut, Sercan Aksoy, Aytekin Akyol, Yasser Riazalhosseini, Pouria Jandaghi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications
Nature Communications
Chemoresistance is a major obstacle in triple negative breast cancer (TNBC), the most aggressive breast cancer subtype. Here we identify hypoxia-induced ECM re-modeler, lysyl oxidase (LOX) as a key inducer of chemoresistance by developing chemoresist
Autor:
Holger Richly, Aysegul Kaymak
Publikováno v:
Cell Cycle. 15:3306-3317
In the present study we addressed the function of the transcriptional activator Zrf1 in the generation of the 3 germ layers during in vitro development. Currently, Zrf1 is rather regarded as a factor that drives the expression of neuronal genes. Here
Publikováno v:
Oncotarget
Breast cancer is one of the most common malignancies among women which is often treated with hormone therapy and chemotherapy. Despite the improvements in detection and treatment of breast cancer, the vast majority of breast cancer patients are diagn
Autor:
Deniz Ogut, Ceren Gonen Korkmaz, Mehmet Zuhuri Arun, Aysegul Kaymak, Buket Reel, Serap Cilaker Micili, Gokce Yildirim, Bekir Ugur Ergur
Publikováno v:
Journal of Cancer
WOS: 000360298900013
PubMed ID: 26366216
Discoidin Domain Receptors (DDR1/DDR2) are tyrosine kinase receptors which are activated by collagen. DDR signalling regulates cell migration, proliferation, apoptosis and matrix metalloproteinase (M
PubMed ID: 26366216
Discoidin Domain Receptors (DDR1/DDR2) are tyrosine kinase receptors which are activated by collagen. DDR signalling regulates cell migration, proliferation, apoptosis and matrix metalloproteinase (M
Autor:
Deniz Ogut, Buket Reel, Mehmet Zuhuri Arun, Gulnur Sevin, Ceren Gonen-Korkmaz, Gokce Yildirim, Goksel Gokce, Aysegul Kaymak
Publikováno v:
Experimental and Therapeutic Medicine
WOS: 000345948000005
Prostate cancer is the second leading cause of morbidity and mortality in males in the Western world. In the present study, LNCaP, which is an androgen receptor-positive and androgen-responsive prostate cancer cell line deri
Prostate cancer is the second leading cause of morbidity and mortality in males in the Western world. In the present study, LNCaP, which is an androgen receptor-positive and androgen-responsive prostate cancer cell line deri
Autor:
Mehmet Zuhuri Arun, Buket Reel, Aysegul Kaymak, Mazen Saeed Abdulaziz, Gulnur Sevin, Deniz Ogut, Ceren Gonen-Korkmaz, Günay Yetik Anacak, Lokman Varisli, Gokce Yıldırım, Goksel Gokce
Publikováno v:
Journal of Cell Signaling.
Prostate cancer studies focus on identification of androgen receptor (AR) regulated genes that are also highly expressed in the prostate. As a promising candidate, STAMP family genes STAMP1/STEAP2, STAMP2/STEAP4 and STEAP3 are involved in apoptosisan