Výsledky vyhledávání - "Aysegul Kascatan-Nebioglu"

In Vitro and Murine Efficacy and Toxicity Studies of Nebulized SCC1, a Methylated Caffeine-Silver(I) Complex, for Treatment of Pulmonary Infections

Autor: Khadijah M. Hindi, Wiley J. Youngs, Lisa A. Hogue, Ravy K. Vajravelu, Carolyn L. Cannon, Aida Ibricevic, George H. Capps, Steven L. Brody, Michael J. Walter, Aysegul Kascatan-Nebioglu

Publikováno v: Antimicrobial Agents and Chemotherapy. 53:3285-3293

The expanding clinical challenge of respiratory tract infections due to resistant bacteria necessitates the development of new forms of therapy. The development of a compound composed of silver coupled to a methylated caffeine carrier (silver carbene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67d08e16ac3d4053219988ee329b448a
https://doi.org/10.1128/aac.00314-09

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Synthesis and in vitro Efficacy Studies of Silver Carbene Complexes on Biosafety Level 3 Bacteria

Autor: Khadijah M. Hindi, Jeff G. Leid, Barbara M. Judy, Julia K. Hilliard, Aysegul Kascatan-Nebioglu, Emily K. Cope, Brian D. Wright, Matthew J. Panzner, Arpaporn Deeraksa, Rebekah J. Mallett, Wiley J. Youngs, Alyssa Smith, Carolyn L. Cannon, D. Mark Estes, Alfredo G. Torres, Christine E. Hovis

Publikováno v: European Journal of Inorganic Chemistry. 2009:1739-1745

A series of N-heterocyclic carbene silver complexes have been synthesized and tested against the select group of bio-safety level 3 bacteria Burkholderia pseudomallei, Burkholderia mallei, Bacillus anthracis, methicillin-resistant Staphylococcus aure

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd777b1b229ea4ad7150e00d3e36a0f5
https://doi.org/10.1002/ejic.200801159

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N-Heterocyclic carbene–silver complexes: A new class of antibiotics

Autor: Aysegul Kascatan-Nebioglu, Wiley J. Youngs, Carolyn L. Cannon, Claire A. Tessier, Matthew J. Panzner

Publikováno v: Coordination Chemistry Reviews. 251:884-895

N-Heterocyclic carbene (NHC)–silver complexes were synthesized from pyridine linked pincer ligands and methylated caffeine. Pincer NHC–silver complexes were found to have more potent antimicrobial activity than the conventionally used silver anti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9429844e3d03fab5e5ddb4bb32580e9f
https://doi.org/10.1016/j.ccr.2006.08.019

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Synthesis from Caffeine of a Mixed N-Heterocyclic Carbene−Silver Acetate Complex Active against Resistant Respiratory Pathogens

Autor: Abdulkareem Melaiye, Seth D. Crosby, Marvin Coughenour, Christine E. Hovis, Wiley J. Youngs, Amy Milsted, Semih Durmus, Lisa A. Hogue, Carolyn L. Cannon, Claire A. Tessier, Daniel Ely, Aysegul Kascatan-Nebioglu, Matthew J. Panzner, Khadijah M. Hindi, Rebekah J. Mallett

Publikováno v: Journal of Medicinal Chemistry. 49:6811-6818

The bis(N-heterocyclic carbene) (NHC) silver complex, 3, with a methyl carbonate anion was formed from the reaction of the iodide salt of methylated caffeine, 1, with silver (I) oxide in methanol. Attempts to crystallize this complex from a mixture o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b40dc0cd0c1751184b520416409b4b8d
https://doi.org/10.1021/jm060711t

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Synthesis and Structural Characterization of N-Heterocyclic Carbene Complexes of Silver(I) and Rhodium(I) from Caffeine

Autor: Wiley J. Youngs, Matthew J. Panzner, Jered C. Garrison, Claire A. Tessier, Aysegul Kascatan-Nebioglu

Publikováno v: Organometallics. 23:1928-1931

The imidazolium cation 1,3,7,9-tetramethylxanthinium methyl sulfate (1a) is obtained by the reaction of caffeine with dimethyl sulfate. The anion exchange of 1a gives 1,3,7,9-tetramethylxanthinium hexafluorophosphate (1b). Ligand 1a reacts with Ag2O

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b036561ab2e036e1f69685d54317f0a9
https://doi.org/10.1021/om030689r

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