Zobrazeno 1 - 10
of 559
pro vyhledávání: '"Aysegul A, Sahin"'
Autor:
Uyen Q. Le, Nanyue Chen, Seetharaman Balasenthil, Eugene Lurie, Fei Yang, Suyu Liu, Laura Rubin, Luisa Maren Solis Soto, Maria Gabriela Raso, Harsh Batra, Aysegul A. Sahin, Ignacio I. Wistuba, Ann McNeill Killary
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Triple negative breast cancer (TNBC) is a disease of poor prognosis, with the majority classified as the basal-like subtype associated with epithelial-mesenchymal transition and metastasis. Because basal breast cancers originate from prolife
Externí odkaz:
https://doaj.org/article/b9e81eddcc574b83a9261ff9ed2b1014
Autor:
Lan Zheng, Rajyalakshmi Luthra, Hector A. Alvarez, F. Anthony San Lucas, Dzifa Y. Duose, Ignacio I. Wistuba, Gregory N. Fuller, Leomar Y. Ballester, Sinchita Roy-Chowdhuri, Keith J. Sweeney, Asif Rashid, Richard K. Yang, Wei Chen, Audrey Liu, Yun Wu, Constance Albarracin, Keyur P. Patel, Mark J. Routbort, Aysegul A. Sahin, Qingqing Ding, Hui Chen
Publikováno v:
Cancers, Vol 16, Iss 1, p 6 (2023)
Epidermal growth factor receptor variant III (EGFRvIII, the deletion of exons 2–7) is a recurrent intragenic EGFR::EGFR.E1E8 fusion that occurs in high-grade gliomas. The presence of EGFRvIII in other solid tumors has not been well characterized. W
Externí odkaz:
https://doaj.org/article/628146eb0ef94163a69f4c5c9ad0399b
Publikováno v:
Cancers, Vol 15, Iss 22, p 5491 (2023)
The second most common breast carcinoma, invasive lobular carcinoma, accounts for approximately 15% of tumors of breast origin. Its incidence has increased in recent times due in part to hormone replacement therapy and improvement in diagnostic modal
Externí odkaz:
https://doaj.org/article/9740ae566d1c46e79a314b02c53026fb
Autor:
Brooke B. Bartow, Gene P. Siegal, Ceren Yalniz, Ahmed M. Elkhanany, Lei Huo, Qingqing Ding, Aysegul A. Sahin, Hua Guo, Cristina Magi-Galluzzi, Shuko Harada, Xiao Huang
Publikováno v:
Cancers, Vol 15, Iss 9, p 2524 (2023)
Poly (adenosine diphosphate-ribose) polymerase inhibitors (PARPis) have demonstrated antitumor activity in cancers with a homologous recombination deficiency (HRD) and have recently been approved by the FDA for the treatment of germline BRCA1/2-mutat
Externí odkaz:
https://doaj.org/article/4f6181383d624a61afeee2b263e082a2
Autor:
Minhua Wang, Qingqing Ding, Jun Gu, Steven M. Sfamenos, Lei Huo, Zhenya Tang, Hongxia Sun, Melissa Robinson, Guilin Tang, Bora Lim, Yun Wu, Constance T. Albarracin, Aysegul A. Sahin, Hui Chen
Publikováno v:
Clinical Breast Cancer. 23:415-422
Autor:
Debasish Tripathy, Khoa Nguyen, Stanley Ly, Vivek Anand, Fouad El-Dana, Yiming Cai, Shirong Cai, Helen Piwnica-Worms, Aysegul A Sahin, Michael Andreeff, Venkata Lokesh Battula
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype with no effective standard therapy. Breast cancer stem-like cells (BCSCs) in primary TNBCs are reported to be responsible for metastatic spread of the diseas
Externí odkaz:
https://doaj.org/article/bade9203487f4305b597d0fd3a2f9118
Autor:
Santanu Adhikary, Deepavali Chakravarti, Christopher Terranova, Isha Sengupta, Mayinuer Maitituoheti, Anirban Dasgupta, Dushyant Kumar Srivastava, Junsheng Ma, Ayush T. Raman, Emily Tarco, Aysegul A. Sahin, Roland Bassett, Fei Yang, Coya Tapia, Siddhartha Roy, Kunal Rai, Chandrima Das
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
H2B monoubiquitination is implicated in oncogenesis. Here, the authors show that UBR7 PHD finger is a H2BK120 monoubiquitin ligase that acts a tumour suppressor in breast cancer by suppressing gene expression for EMT, while promoting expression of CD
Externí odkaz:
https://doaj.org/article/d9e45b04af2247a480020df6e19b7638
Autor:
Nour Abuhadra, Ryan Sun, Jennifer K. Litton, Gaiane M. Rauch, Clinton Yam, Jeffrey T. Chang, Sahil Seth, Roland Bassett, Bora Lim, Alastair M. Thompson, Elizabeth Mittendorf, Beatriz E. Adrada, Senthil Damodaran, Jason White, Elizabeth Ravenberg, Rosalind Candelaria, Banu Arun, Naoto T. Ueno, Lumarie Santiago, Sadia Saleem, Sausan Abouharb, Rashmi K. Murthy, Nuhad Ibrahim, Aysegul A. Sahin, Vicente Valero, William Fraser Symmans, Debu Tripathy, Stacy Moulder, Lei Huo
Publikováno v:
Cancers, Vol 14, Iss 5, p 1323 (2022)
High stromal tumor-infiltrating lymphocytes (sTILs) are associated with an improved pathologic complete response (pCR) and survival in triple-negative breast cancer (TNBC). We hypothesized that high baseline sTILs would have a favorable prognostic im
Externí odkaz:
https://doaj.org/article/952af2308a3544ecb401c3451546048a
Autor:
Puneet Singh, MD, Marion E. Scoggins, MD, Aysegul A. Sahin, MD, Rosa F. Hwang, MD, Henry M. Kuerer, MD, PhD, Abigail S. Caudle, MD, Elizabeth A. Mittendorf, MD, PhD, Alastair M. Thompson, MBChB, MD, Isabelle Bedrosian, MD, Mediget Teshome, MD, Sarah M. DeSnyder, MD, Funda Meric-Bernstam, MD, Kelly K. Hunt, MD
Publikováno v:
Annals of Surgery Open, Vol 1, Iss 2, p e008 (2020)
Objective:. A prospective, phase IV study was conducted to assess the effectiveness of Magseed to localize breast lesions requiring surgical excision. Background:. Since Food and Drug Administration approval in 2016, Magseed has been increasingly use
Externí odkaz:
https://doaj.org/article/2ca606fcc74e4a6b954d5ba0508ce852
Publikováno v:
Seminars in Diagnostic Pathology. 39:313-321
Due to the high prevalence of breast cancer in the female, a metastasis from primary breast cancer is usually considered in the differential diagnosis of metastatic carcinoma in the female patient, even for those without a history of breast cancer, a