Zobrazeno 1 - 10
of 555
pro vyhledávání: '"Aysegul A, Sahin"'
Publikováno v:
Human Pathology Reports, Vol 37, Iss , Pp 300755- (2024)
Secretory breast carcinoma is a rare form of breast cancer characterized by low-grade histology, presence of intracellular eosinophilic secretions, and ETV6-NTRK3 fusion. Although several studies have explored the histopathologic features of secretor
Externí odkaz:
https://doaj.org/article/2c1cd609b46c4a598dc2a64acdb21465
Autor:
Uyen Q. Le, Nanyue Chen, Seetharaman Balasenthil, Eugene Lurie, Fei Yang, Suyu Liu, Laura Rubin, Luisa Maren Solis Soto, Maria Gabriela Raso, Harsh Batra, Aysegul A. Sahin, Ignacio I. Wistuba, Ann McNeill Killary
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Triple negative breast cancer (TNBC) is a disease of poor prognosis, with the majority classified as the basal-like subtype associated with epithelial-mesenchymal transition and metastasis. Because basal breast cancers originate from prolife
Externí odkaz:
https://doaj.org/article/b9e81eddcc574b83a9261ff9ed2b1014
Autor:
Santanu Adhikary, Deepavali Chakravarti, Christopher Terranova, Isha Sengupta, Mayinuer Maitituoheti, Anirban Dasgupta, Dushyant Kumar Srivastava, Junsheng Ma, Ayush T. Raman, Emily Tarco, Aysegul A. Sahin, Roland Bassett, Fei Yang, Coya Tapia, Siddhartha Roy, Kunal Rai, Chandrima Das
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
H2B monoubiquitination is implicated in oncogenesis. Here, the authors show that UBR7 PHD finger is a H2BK120 monoubiquitin ligase that acts a tumour suppressor in breast cancer by suppressing gene expression for EMT, while promoting expression of CD
Externí odkaz:
https://doaj.org/article/d9e45b04af2247a480020df6e19b7638
Autor:
Minhua Wang, Qingqing Ding, Jun Gu, Steven M. Sfamenos, Lei Huo, Zhenya Tang, Hongxia Sun, Melissa Robinson, Guilin Tang, Bora Lim, Yun Wu, Constance T. Albarracin, Aysegul A. Sahin, Hui Chen
Publikováno v:
Clinical Breast Cancer. 23:415-422
Autor:
Debasish Tripathy, Khoa Nguyen, Stanley Ly, Vivek Anand, Fouad El-Dana, Yiming Cai, Shirong Cai, Helen Piwnica-Worms, Aysegul A Sahin, Michael Andreeff, Venkata Lokesh Battula
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype with no effective standard therapy. Breast cancer stem-like cells (BCSCs) in primary TNBCs are reported to be responsible for metastatic spread of the diseas
Externí odkaz:
https://doaj.org/article/bade9203487f4305b597d0fd3a2f9118
Autor:
Puneet Singh, MD, Marion E. Scoggins, MD, Aysegul A. Sahin, MD, Rosa F. Hwang, MD, Henry M. Kuerer, MD, PhD, Abigail S. Caudle, MD, Elizabeth A. Mittendorf, MD, PhD, Alastair M. Thompson, MBChB, MD, Isabelle Bedrosian, MD, Mediget Teshome, MD, Sarah M. DeSnyder, MD, Funda Meric-Bernstam, MD, Kelly K. Hunt, MD
Publikováno v:
Annals of Surgery Open, Vol 1, Iss 2, p e008 (2020)
Objective:. A prospective, phase IV study was conducted to assess the effectiveness of Magseed to localize breast lesions requiring surgical excision. Background:. Since Food and Drug Administration approval in 2016, Magseed has been increasingly use
Externí odkaz:
https://doaj.org/article/2ca606fcc74e4a6b954d5ba0508ce852
Autor:
James Crespo, Hongxia Sun, Jimin Wu, Qing-Qing Ding, Guilin Tang, Melissa K Robinson, Hui Chen, Aysegul A Sahin, Bora Lim
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241775 (2020)
PurposeThe 2018 American Society of Clinical Oncology/College of American Pathologists (ASCO/CAP) guideline on HER2 testing in breast cancer permits reclassification of cases with HER2-equivocal results by FISH. The impact of such reclassification is
Externí odkaz:
https://doaj.org/article/878ddac6c1934e4db03bd3c661411f1a
Autor:
Alexes C. Daquinag, Ali Dadbin, Brad Snyder, Xiaoping Wang, Aysegul A. Sahin, Naoto T. Ueno, Mikhail G. Kolonin
Publikováno v:
Molecular Therapy: Oncolytics, Vol 6, Iss C, Pp 1-9 (2017)
Adipose stromal cells (ASCs) have been identified as a mesenchymal cell population recruited from white adipose tissue (WAT) by tumors and supporting cancer progression. We have previously reported the existence of a non-glycanated decorin isoform (n
Externí odkaz:
https://doaj.org/article/1081b6e0953d48c9b677692a6b96f8eb
Publikováno v:
Seminars in Diagnostic Pathology. 39:313-321
Due to the high prevalence of breast cancer in the female, a metastasis from primary breast cancer is usually considered in the differential diagnosis of metastatic carcinoma in the female patient, even for those without a history of breast cancer, a
Autor:
Brooke B. Bartow, Gene P. Siegal, Ceren Yalniz, Ahmed M. Elkhanany, Lei Huo, Qingqing Ding, Aysegul A. Sahin, Hua Guo, Cristina Magi-Galluzzi, Shuko Harada, Xiao Huang
Publikováno v:
Cancers; Volume 15; Issue 9; Pages: 2524
Poly (adenosine diphosphate-ribose) polymerase inhibitors (PARPis) have demonstrated antitumor activity in cancers with a homologous recombination deficiency (HRD) and have recently been approved by the FDA for the treatment of germline BRCA1/2-mutat