Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ayse Nur-Menevse"'
Autor:
Jessica Pinkert, Hans-Henning Boehm, Mark Trautwein, Wolf-Dietrich Doecke, Florian Wessel, Yingzi Ge, Eva Maria Gutierrez, Rafael Carretero, Christoph Freiberg, Uwe Gritzan, Merlin Luetke-Eversloh, Sven Golfier, Oliver Von Ahsen, Valentina Volpin, Antonio Sorrentino, Anchana Rathinasamy, Maria Xydia, Robert Lohmayer, Julian Sax, Ayse Nur-Menevse, Abir Hussein, Slava Stamova, Georg Beckmann, Julian Marius Glueck, Dorian Schoenfeld, Joerg Weiske, Dieter Zopf, Rienk Offringa, Bertolt Kreft, Philipp Beckhove, Joerg Willuda
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), a cell surface receptor, is expressed on normal epithelial tissue and highly expressed in cancers of high unmet medical need, such as non-small cell lung, pancreatic, and colorectal
Externí odkaz:
https://doaj.org/article/b51b522082204e19b3b78844000d71d5
Autor:
Franziska Christine Sanna, Iva Benešová, Philip Pervan, Adriana Krenz, Alexander Wurzel, Robert Lohmayer, Jasmin Mühlbauer, Amélie Wöllner, Nina Köhl, Ayse Nur Menevse, Slava Stamova, Valentina Volpin, Philipp Beckhove, Maria Xydia
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IL-32 expression is important for pathogen clearance but detrimental in chronic inflammation, autoimmunity, and cancer. T cells are major IL-32 producers in these diseases and key mediators of pathogen and tumor elimination but also autoimmune destru
Externí odkaz:
https://doaj.org/article/716aa81b1a1448fd91912bdc2ffe9517
Autor:
Nathalie Babl, Joshua Hofbauer, Carina Matos, Florian Voll, Ayse Nur Menevse, Michael Rechenmacher, Ruth Mair, Philipp Beckhove, Wolfgang Herr, Peter J. Siska, Kathrin Renner, Marina Kreutz, Annette Schnell
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionThe discovery of immune checkpoints and the development of their specific inhibitors was acclaimed as a major breakthrough in cancer therapy. However, only a limited patient cohort shows sufficient response to therapy. Hence, there is a n
Externí odkaz:
https://doaj.org/article/665d9c3a8e194fc4aff448d9891a418f
Autor:
Frank K. Braun, Tanja Rothhammer-Hampl, Julia Lorenz, Sandra Pohl, Ayse-Nur Menevse, Arabel Vollmann-Zwerenz, Elisabeth Bumes, Maren Büttner, Saida Zoubaa, Martin Proescholdt, Nils O. Schmidt, Peter Hau, Philipp Beckhove, Beate Winner, Markus J. Riemenschneider
Publikováno v:
Cells, Vol 12, Iss 14, p 1856 (2023)
Conventional 2D cultures are commonly used in cancer research though they come with limitations such as the lack of microenvironment or reduced cell heterogeneity. In this study, we investigated in what respect a scaffold-based (Matrigel™) 3D cultu
Externí odkaz:
https://doaj.org/article/34a1a8f1e65a4f44afca380bf5cfda63
Autor:
Kathrin Renner, Christina Bruss, Annette Schnell, Gudrun Koehl, Holger M. Becker, Matthias Fante, Ayse-Nur Menevse, Nathalie Kauer, Raquel Blazquez, Lisa Hacker, Sonja-Maria Decking, Toszka Bohn, Stephanie Faerber, Katja Evert, Lisa Aigle, Sabine Amslinger, Maria Landa, Oscar Krijgsman, Elisa A. Rozeman, Christina Brummer, Peter J. Siska, Katrin Singer, Stefanie Pektor, Matthias Miederer, Katrin Peter, Eva Gottfried, Wolfgang Herr, Ibtisam Marchiq, Jacques Pouyssegur, William R. Roush, SuFey Ong, Sarah Warren, Tobias Pukrop, Philipp Beckhove, Sven A. Lang, Tobias Bopp, Christian U. Blank, John L. Cleveland, Peter J. Oefner, Katja Dettmer, Mark Selby, Marina Kreutz
Publikováno v:
Cell Reports, Vol 29, Iss 1, Pp 135-150.e9 (2019)
Summary: Tumor-derived lactic acid inhibits T and natural killer (NK) cell function and, thereby, tumor immunosurveillance. Here, we report that melanoma patients with high expression of glycolysis-related genes show a worse progression free survival
Externí odkaz:
https://doaj.org/article/ca9683bbded745c68d1cf4f71ab912e4
Autor:
Thomas Walle, Joscha A. Kraske, Boyu Liao, Bénédicte Lenoir, Carmen Timke, Emilia von Bohlen und Halbach, Florian Tran, Paul Griebel, Dorothee Albrecht, Azaz Ahmed, Meggy Suarez-Carmona, Alejandro Jiménez-Sánchez, Tizian Beikert, Alexandra Tietz-Dahlfuß, Ayse Nur Menevse, Gabriele Schmidt, Manuela Brom, Jens H. W. Pahl, Wiebke Antonopoulos, Matthias Miller, Ramon Lopez Perez, Felix Bestvater, Nathalia A. Giese, Philipp Beckhove, Philip Rosenstiel, Dirk Jäger, Oliver Strobel, Dana Pe’er, Niels Halama, Jürgen Debus, Adelheid Cerwenka, Peter E. Huber
Publikováno v:
Science advances. 8(12)
Radiotherapy is a mainstay cancer therapy whose antitumor effects partially depend on T cell responses. However, the role of Natural Killer (NK) cells in radiotherapy remains unclear. Here, using a reverse translational approach, we show a central ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc14267c6f46fa5e76b411188d831c27
https://pubmed.ncbi.nlm.nih.gov/35319989
https://pubmed.ncbi.nlm.nih.gov/35319989
Autor:
Christian H. Wetzel, Hartmut Goldschmidt, Vladimir M. Milenkovic, Mark Berneburg, Mathias Witzens-Harig, György Vereb, Ayse Nur Menevse, Arpad Szoor, Michael Boutros, Antonio Sorrentino, Chih-Yeh Chen, Anchana Rathinasamy, Philipp Beckhove, Sebastian Haferkamp, Klaus G. Griewank, Martin Ehrenschwender, Gertrud Knoll, Tillmann Michels, Madlen Ditz, Valentina Volpin, Anja Seckinger, Dirk Hose, Nisit Khandelwal
Publikováno v:
Cancer Immunology Research. 8:1163-1179
The success of cancer immunotherapy is limited by resistance to immune checkpoint blockade. We therefore conducted a genetic screen to identify genes that mediated resistance against CTLs in anti–PD-L1 treatment–refractory human tumors. Using PD-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff975b35c4053903783cb9175f1f3d58
https://doi.org/10.1158/2326-6066.cir-19-0608
https://doi.org/10.1158/2326-6066.cir-19-0608
Autor:
Jessica Pinkert, Hans-Henning Boehm, Mark Trautwein, Wolf-Dietrich Doecke, Florian Wessel, Yingzi Ge, Eva Maria Gutierrez, Rafael Carretero, Christoph Freiberg, Uwe Gritzan, Merlin Luetke-Eversloh, Sven Golfier, Oliver Von Ahsen, Valentina Volpin, Antonio Sorrentino, Anchana Rathinasamy, Maria Xydia, Robert Lohmayer, Julian Sax, Ayse Nur-Menevse, Abir Hussein, Slava Stamova, Georg Beckmann, Julian Marius Glueck, Dorian Schoenfeld, Joerg Weiske, Dieter Zopf, Rienk Offringa, Bertolt Kreft, Philipp Beckhove, Joerg Willuda
Publikováno v:
Oncoimmunology
article-version (VoR) Version of Record
OncoImmunology, Vol 11, Iss 1 (2022)
article-version (VoR) Version of Record
OncoImmunology, Vol 11, Iss 1 (2022)
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), a cell surface receptor, is expressed on normal epithelial tissue and highly expressed in cancers of high unmet medical need, such as non-small cell lung, pancreatic, and colorectal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4287e8bd089e154a63f7b8bf72626538
https://doi.org/10.1080/2162402x.2021.2008110
https://doi.org/10.1080/2162402x.2021.2008110
Autor:
Tobias Ettl, Antonio Sorrentino, Matthias G. Hautmann, Daniela Schulz, Torsten E. Reichert, Ayse-Nur Menevse, Richard Bauer, Gero Brockhoff, Philipp Beckhove, Irene Stancev
Publikováno v:
Oncotarget
// Daniela Schulz 1 , Irene Stancev 1 , Antonio Sorrentino 2 , Ayse-Nur Menevse 2 , Philipp Beckhove 2 , Gero Brockhoff 3 , Matthias Gunther Hautmann 4 , Torsten Erich Reichert 1 , Richard Josef Bauer 1, 5 and Tobias Ettl 1 1 Department of Oral and M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937c58a0e047b4c50679d39e84db4e10
http://europepmc.org/articles/PMC6355177
http://europepmc.org/articles/PMC6355177
Autor:
Antonio Sorrentino, Ayse Nur Menevse, Tillmann Michels, Valentina Volpin, Franziska Christine Durst, Julian Sax, Maria Xydia, Abir Hussein, Slava Stamova, Steffen Spoerl, Nicole Heuschneider, Jasmin Muehlbauer, Katharina Marlene Jeltsch, Anchana Rathinasamy, Melanie Werner-Klein, Marco Breinig, Damian Mikietyn, Christian Kohler, Isabel Poschke, Sabrina Purr, Olivia Reidell, Catarina Martins Freire, Rienk Offringa, Claudia Gebhard, Rainer Spang, Michael Rehli, Michael Boutros, Christian Schmidl, Nisit Khandelwal, Philipp Beckhove
Publikováno v:
Journal for ImmunoTherapy of Cancer. 10:e004258
BackgroundCancer immunotherapeutic strategies showed unprecedented results in the clinic. However, many patients do not respond to immuno-oncological treatments due to the occurrence of a plethora of immunological obstacles, including tumor intrinsic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce9b03b714e0e29354c34b37a2f129d
https://doi.org/10.1136/jitc-2021-004258
https://doi.org/10.1136/jitc-2021-004258