Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ayse Gulten Kantarci"'
Autor:
Ezgi Oner, Mustafa Kotmakci, Anne-Marie Baird, Steven G. Gray, Bilge Debelec Butuner, Emir Bozkurt, Ayse Gulten Kantarci, Stephen P. Finn
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-20 (2021)
Abstract Background siRNAs hold a great potential for cancer therapy, however, poor stability in body fluids and low cellular uptake limit their use in the clinic. To enhance the bioavailability of siRNAs in tumors, novel, safe, and effective carrier
Externí odkaz:
https://doaj.org/article/dfd69785a72643ba9dfc925960946367
Autor:
Aytül Gül, Sedef Erkunt Alak, Hüseyin Can, Muhammet Karakavuk, Gülay Korukluoğlu, Ayşe Başak Altaş, Ceren Gül, Tuğba Karakavuk, Ahmet Efe Köseoğlu, Hivda Ülbeği Polat, Hilal Yazıcı Malkoçoğlu, Arzu Taş Ekiz, İrem Abacı, Özge Aksoy, Hakan Enül, Cumhur Adıay, Serdar Uzar, Fahriye Saraç, Cemal Ün, Adnan Yüksel Gürüz, Ayşe Gülten Kantarcı, Hasan Akbaba, Gülşah Erel Akbaba, Habibe Yılmaz, Aysu Değirmenci Döşkaya, Meltem Taşbakan, Hüsnü Pullukçu, Ercüment Karasulu, Şaban Tekin, Mert Döşkaya
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Severe acute respiratory syndrome coronavirus 2 had devastating consequences for human health. Despite the introduction of several vaccines, COVID-19 continues to pose a serious health risk due to emerging variants of concern. DNA vaccines g
Externí odkaz:
https://doaj.org/article/70a1957a12804e069e8928eedb04be9a
Autor:
Stephen P. Finn, Mustafa Kotmakçı, Steven G. Gray, Emir Bozkurt, Bilge Debeleç Bütüner, Ayse Gulten Kantarci, Ezgi Oner, Anne-Marie Baird
Publikováno v:
Journal of Nanobiotechnology
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-20 (2021)
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-20 (2021)
Background: siRNAs hold a great potential for cancer therapy, however, poor stability in body fluids and low cellular uptake limit their use in the clinic. To enhance the bioavailability of siRNAs in tumors, novel, safe, and effective carriers are ne
We aimed to develop nanostructured lipid carriers (NLCs) displaying similar characteristics - particle size, polydispersity index, and zeta potential - with the model solid lipid nanoparticles (SLNs) for better comparability. By considering the hydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d97933c455818075ae2f65124492cb
https://hdl.handle.net/11454/62381
https://hdl.handle.net/11454/62381
Publikováno v:
Journal of Drug Delivery Science and Technology. 66:102670
Most chemotherapeutics induce apoptosis by creating DNA damage in tumor cells. However, high expression of Sirtuin 1 (SIRT1), which is a histone deacetylase activates DNA repair mechanisms leading to the repair of chemotherapeutic-induced DNA damage
Publikováno v:
Journal of Drug Delivery Science and Technology. 36:161-167
In this study, we aimed to develop a novel protein - nanoencapsulated system for oral administration. For this purpose, insulin was selected as the model drug. Insulin loaded chitosan nanoparticles (INS-CS-NPs) were obtained by ionic gelation between
EgeUn###
Escape from apoptosis, one of the characteristic features of cancer cells, is a case that reduces the therapeutic efficacy of apoptosis-inducing molecules used in the cancer treatment. Stabilization of the P53 protein, which is responsi
Escape from apoptosis, one of the characteristic features of cancer cells, is a case that reduces the therapeutic efficacy of apoptosis-inducing molecules used in the cancer treatment. Stabilization of the P53 protein, which is responsi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3e1957cda58ef4c9e4d5ddeebdb11c7
https://hdl.handle.net/11454/28868
https://hdl.handle.net/11454/28868
Autor:
Pierre J. Obeid, Ayse Gulten Kantarci, Gülşah Erel-Akbaba, Max Zinter, Bakhos A. Tannous, Ralph Weissleder, E. Antonio Chiocca, Tian Tian, Litia Carvalho, Hasan Akbaba
EgeUn###
Targeted therapy against the programmed cell death ligand-1 (PD-L1) blockade holds considerable promise for the treatment of different tumor types; however, little effect has been observed against gliomas thus far. Effective glioma ther
Targeted therapy against the programmed cell death ligand-1 (PD-L1) blockade holds considerable promise for the treatment of different tumor types; however, little effect has been observed against gliomas thus far. Effective glioma ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa2bbf52d5f52d17243ce20cd3b32779
https://hdl.handle.net/11454/24886
https://hdl.handle.net/11454/24886
WOS: 000438786000019
In this study, we aimed to develop a novel positive charged nucleic acid delivery system for the treatment of glioblastoma. For this purpose, Epidermal Growth Factor Receptor (EGFR) which plays a prominent role in glioblasto
In this study, we aimed to develop a novel positive charged nucleic acid delivery system for the treatment of glioblastoma. For this purpose, Epidermal Growth Factor Receptor (EGFR) which plays a prominent role in glioblasto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e21b693c4e25f732a93f6db56c314e
https://aperta.ulakbim.gov.tr/record/37003
https://aperta.ulakbim.gov.tr/record/37003
2-s2.0-85040328125
In this study, we aimed to develop and evaluate an effective system for nucleic acid delivery. For this purpose, shRNA-encoding plasmid against 5-? reductase (p5?-Red) activity was selected as a model. In order to achieve the
In this study, we aimed to develop and evaluate an effective system for nucleic acid delivery. For this purpose, shRNA-encoding plasmid against 5-? reductase (p5?-Red) activity was selected as a model. In order to achieve the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd4310c0b29c31edd0600ba3f21d1fb
https://hdl.handle.net/11454/70716
https://hdl.handle.net/11454/70716