Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ayrin Kok"'
Autor:
Roshan M. Kumar, Julie Prigent, Hombline Poullain, Ayrin Kok, Carine George, Sami Ellouze, Yun-Yueh Lu, Rebecca Silver, Clarisse Monchecourt, Ross B. Fulton, Qian Zhang, Nicola Beltraminelli, Bernhard Moser, Francisco Adrian, Liang Schweizer
Publikováno v:
Cancer Research. 82:2899-2899
Regulatory T cells (Tregs) contribute to immunosuppression within the tumor microenvironment and have been associated with poor outcomes in a range of cancers. Targeted depletion of tumor-infiltrating Tregs (TITRs) is an attractive therapeutic strate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0af7c3d102d93c864a055c0053f0633e
https://doi.org/10.1158/1538-7445.am2022-2899
https://doi.org/10.1158/1538-7445.am2022-2899
Autor:
Nicola Beltraminelli, Mingjie Chen, Francisco Adrian, Stephanie Beq, Hombline Poullain, Clarisse Monchecourt, Jean Wang, Sami Ellouze, Carine George, Juying Li, Germain Margall-Ducos, Qian Zhang, Ayrin Kok, Yun-Yueh Lu, Muriel D. David, Liang Schweizer
Publikováno v:
Cancer Research. 81:1843-1843
CXCR5 is a seven transmembrane protein coupled to protein G(i) expressed mainly on mature, resting B cells, follicular helper T cells (TFH), tonsillar B cells, and B cell lymphoma cells. CXCR5 is activated by its ligand CXCL13 and involved in cell mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe2fca74efbd0ee62050aee879c75264
https://doi.org/10.1158/1538-7445.am2021-1843
https://doi.org/10.1158/1538-7445.am2021-1843
Autor:
Julie Prigent, Annaëlle Jarossay, Cyril Planchais, Caroline Eden, Jérémy Dufloo, Ayrin Kök, Valérie Lorin, Oxana Vratskikh, Thérèse Couderc, Timothée Bruel, Olivier Schwartz, Michael S. Seaman, Oliver Ohlenschläger, Jordan D. Dimitrov, Hugo Mouquet
Publikováno v:
Cell Reports, Vol 23, Iss 9, Pp 2568-2581 (2018)
Human high-affinity antibodies to pathogens often recognize unrelated ligands. The molecular origin and the role of this polyreactivity are largely unknown. Here, we report that HIV-1 broadly neutralizing antibodies (bNAbs) are frequently polyreactiv
Externí odkaz:
https://doaj.org/article/94e93b8b4c694f2ab52f103c8961f5f0
Autor:
Cyril Planchais, Ayrin Kök, Alexia Kanyavuz, Valérie Lorin, Timothée Bruel, Florence Guivel-Benhassine, Tim Rollenske, Julie Prigent, Thierry Hieu, Thierry Prazuck, Laurent Lefrou, Hedda Wardemann, Olivier Schwartz, Jordan D. Dimitrov, Laurent Hocqueloux, Hugo Mouquet
Publikováno v:
Cell Reports, Vol 27, Iss 2, Pp 572-585.e7 (2019)
Summary: Mucosal immune responses to HIV-1 involve the recognition of the viral envelope glycoprotein (gp)160 by tissue-resident B cells and subsequent secretion of antibodies. To characterize the B cells “sensing” HIV-1 in the gut of infected in
Externí odkaz:
https://doaj.org/article/23b54c818eae44f5b3af42909e9f4363
Autor:
Mohammad-Ali Jenabian, Nabila Seddiki, Ahmad Yatim, Matthieu Carriere, Anne Hulin, Mehwish Younas, Elnaz Ghadimi, Ayrin Kök, Jean-Pierre Routy, Alain Tremblay, Jean Sévigny, Jean-Daniel Lelievre, Yves Levy
Publikováno v:
PLoS Pathogens, Vol 9, Iss 4, p e1003319 (2013)
The mechanisms by which Regulatory T cells suppress IL-2 production of effector CD4+ T cells in pathological conditions are unclear. A subpopulation of human Treg expresses the ectoenzyme CD39, which in association with CD73 converts ATP/ADP/AMP to a
Externí odkaz:
https://doaj.org/article/d25017a4d436445f9653e87fc9a16d22
Autor:
Maria Nikolova, Matthieu Carriere, Mohammad-Ali Jenabian, Sophie Limou, Mehwish Younas, Ayrin Kök, Sophie Huë, Nabila Seddiki, Anne Hulin, Olivier Delaneau, Hanneke Schuitemaker, Joshua T Herbeck, James I Mullins, Maria Muhtarova, Armand Bensussan, Jean-François Zagury, Jean-Daniel Lelievre, Yves Lévy
Publikováno v:
PLoS Pathogens, Vol 7, Iss 7, p e1002110 (2011)
HIV-1 infection is characterized by a chronic activation of the immune system and suppressed function of T lymphocytes. Regulatory CD4+ CD25(high) FoxP3+CD127(low) T cells (Treg) play a key role in both conditions. Here, we show that HIV-1 positive p
Externí odkaz:
https://doaj.org/article/6978a6a1af86471db9fda97b11c647d1