Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ayon A. Hassan"'
Autor:
Ayon A. Hassan, Margarita Artemenko, Maggie K. S. Tang, Zeyu Shi, Lin-Yu Chen, Hung-Cheng Lai, Zhenyu Yang, Ho-Cheung Shum, Alice S. T. Wong
Publikováno v:
Cell Death and Disease, Vol 13, Iss 6, Pp 1-11 (2022)
Abstract Overcoming drug resistance is an inevitable challenge to the success of cancer treatment. Recently, in ovarian cancer, a highly chemoresistant tumor, we demonstrated an important role of shear stress in stem-like phenotype and chemoresistanc
Externí odkaz:
https://doaj.org/article/c2efad319cb943d690a16c5575e3aabb
Autor:
Shan-Shan Li, Carman K. M. Ip, Matthew Y. H. Tang, Maggie K. S. Tang, Yin Tong, Jiangwen Zhang, Ayon Ahmed Hassan, Abby S. C. Mak, Susan Yung, Tak-Mao Chan, Philip P. Ip, Cheuk Lun Lee, Philip C. N. Chiu, Leo Tsz On Lee, Hung-Cheng Lai, Jin-Zhang Zeng, Ho Cheung Shum, Alice S. T. Wong
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Tumor cell in the peritoneum are often exposed to shear forces generated by ascitic flow during metastasis. Here, the authors show that metastatic cancer stem cells tether more and roll slower than the non-metastatic counterparts, and that sialyl-Lew
Externí odkaz:
https://doaj.org/article/adfaf653b8994433a83662d8754dca91
Publikováno v:
Experimental Cell Research. 416:113150
Among all gynecological malignancies, ovarian cancer (OC) accounts for the highest mortality rate due to high therapeutic resistance, prolonged latency and a lack of effective treatments. This calls for preclinical models that could recapitulate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8890ad652a8c9dddb799d311677b7f06
https://doi.org/10.1016/j.yexcr.2022.113150
https://doi.org/10.1016/j.yexcr.2022.113150
Publikováno v:
Cancers
Cancers, Vol 12, Iss 2238, p 2238 (2020)
Cancers, Vol 12, Iss 2238, p 2238 (2020)
Ovarian cancer is the most lethal gynecological malignancy worldwide. Unlike most other tumor types that metastasize via the vasculature, ovarian cancer metastasizes predominantly via the transcoelomic route within the peritoneal cavity. As cancer me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ddb784d7a0ef4058efe6a03ead2d26a
https://pubmed.ncbi.nlm.nih.gov/32785160
https://pubmed.ncbi.nlm.nih.gov/32785160
Autor:
Hung Cheng Lai, Philip C.N. Chiu, Jin-Zhang Zeng, Yin Tong, Ayon A. Hassan, Matthew Y. H. Tang, Abby S C Mak, Alice S.T. Wong, Leo T. O. Lee, Susan Yung, Jiangwen Zhang, Maggie K.S. Tang, Cheuk Lun Lee, Ho Cheung Shum, Shan-Shan Li, Carman K.M. Ip, Philip P.C. Ip, Tak Mao Chan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Nature Communications
Organ-specific colonization suggests that specific cell–cell recognition is essential. Yet, very little is known about this particular interaction. Moreover, tumor cell lodgement requires binding under shear stress, but not static, conditions. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f528f3dcce4e72bb483cb58b47179fb1
https://doi.org/10.1038/s41467-019-10334-6
https://doi.org/10.1038/s41467-019-10334-6
Publikováno v:
Cancer Research. 80:3707-3707
The tumor microenvironment is actively involved in cancer progression and is becoming an attractive therapeutic target. It is increasingly clear that both biotic and abiotic factors in the microenvironment play a crucial role in disease progression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06d4ec4ca14fb1804d163f09583158c0
https://doi.org/10.1158/1538-7445.am2020-3707
https://doi.org/10.1158/1538-7445.am2020-3707
Autor:
Alice S.T. Wong, Kuang Hong Neoh, Ray P. S. Han, Yukun Sun, Ayon A. Hassan, Kai-Feng Xu, Anqi Chen, Peng Liu
Publikováno v:
Biomaterials. 150
Traditionally, liquid biopsy is a blood test involving the harvesting of tumor materials from peripheral blood. Tumor cells from non-blood body fluids have always been clinically available in cytological examinations but limited for use in differenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cdd23351ac44541992d61a935d37f6a
https://pubmed.ncbi.nlm.nih.gov/29035737
https://pubmed.ncbi.nlm.nih.gov/29035737
Autor:
Alice S.T. Wong, Shan-Shan Li, Carman K.M. Ip, Ayon A. Hassan, Susan Yung, Matthew Y. H. Tang, Ho Cheung Shum, Tak Mao Chan
Publikováno v:
Cancer Research. 77:5885-5885
Metastasis is one of the major challenges for the treatment of ovarian cancer. Unlike other solid tumors, ovarian cancer primarily disseminates within the peritoneal cavity. A crucial step in metastasis formation is the adhesion of ovarian cancer cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72fb37ed2854642b12436a86147e6275
https://doi.org/10.1158/1538-7445.am2017-5885
https://doi.org/10.1158/1538-7445.am2017-5885