Zobrazeno 1 - 10
of 274
pro vyhledávání: '"Ayola A Adegnika"'
Autor:
Bayode R Adegbite, Federico G Gobbi, Cristina Mazzi, Fabrice Beral M'Baidiguim, Anita Lumeka, Andréa R O Obele Ndong, Jean R Edoa, Yabo J Honkpéhèdji, Jeannot F Zinsou, Jean C Dejon-Agobé, Rella Zoleko-Manego, Michael Ramharter, Ayola A Adegnika, Francesca Tamarozzi
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 8, p e0012448 (2024)
BackgroundInfection with the filarial nematode Loa loa, endemic in Central and Western Africa, has been associated with increased morbidity and mortality. A number of reports described the presence of spleen nodules, originating from degenerating mic
Externí odkaz:
https://doaj.org/article/eeaeff4910104e0dab9084ad3d155f1b
Autor:
Haruka Abe, Yuri Ushijima, Rodrigue Bikangui, Georgelin Nguema Ondo, Ayong Moure, Yoric Yali-Assy-Oyamli, Rokusuke Yoshikawa, Bertrand Lell, Ayola A Adegnika, Jiro Yasuda
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 12, p e0010964 (2022)
BackgroundDespite the development of several methods for diagnosing COVID-19, long-term validation of such methods remains limited. In the early phase of the COVID-19 pandemic, we developed a rapid and sensitive diagnostic method based on reverse tra
Externí odkaz:
https://doaj.org/article/1223c6d0c56f404c94982f50980c018c
Autor:
Rella Zoleko-Manego, Dearie G Okwu, Christian Handrich, Lia B Dimessa-Mbadinga, Malick A Akinosho, Wilfrid F Ndzebe-Ndoumba, Saskia D Davi, Daniel Stelzl, Luzia Veletzky, Andrea Kreidenweiss, Tamara Nordmann, Ayola A Adegnika, Bertrand Lell, Peter G Kremsner, Michael Ramharter, Ghyslain Mombo-Ngoma
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 10, p e0010899 (2022)
BackgroundUrogenital schistosomiasis is prevalent in many malaria endemic regions of sub-Saharan Africa and can lead to long-term health consequences if untreated. Antimalarial drugs used to treat uncomplicated malaria have shown to exert some activi
Externí odkaz:
https://doaj.org/article/bdbd6724b22445ba83ae7f4e7ff50d59
Autor:
Madeleine Eunice Betouke Ongwe, Yoanne D Mouwenda, Koen A Stam, Peter G Kremsner, Bertrand Lell, David Diemert, Jeff Bethony, Maria E Bottazzi, Peter J Hotez, Remko V Leeuwen, Martin P Grobusch, Ayola A Adegnika, Oleg A Mayboroda, Maria Yazdanbakhsh
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0275013 (2022)
Metabolomics provides a powerful tool to study physiological changes in response to various perturbations such as vaccination. We explored whether metabolomic changes could be seen after vaccination in a phase I trial where Gabonese adults living eit
Externí odkaz:
https://doaj.org/article/ed445e508fab47d0a4352a9fcd870d4f
Autor:
Yoanne D Mouwenda, Madeleine E Betouke Ongwe, Friederike Sonnet, Koen A Stam, Lucja A Labuda, Sophie De Vries, Martin P Grobusch, Frejus J Zinsou, Yabo J Honkpehedji, Jean-Claude Dejon Agobe, David J Diemert, Remko van Leeuwen, Maria E Bottazzi, Peter J Hotez, Peter G Kremsner, Jeffrey M Bethony, Simon P Jochems, Ayola A Adegnika, Marguerite Massinga Loembe, Maria Yazdanbakhsh
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 10, p e0009732 (2021)
Two hookworm vaccine candidates, Na-GST-1 and Na-APR-1, formulated with Glucopyranosyl Lipid A (GLA-AF) adjuvant, have been shown to be safe, well tolerated, and to induce antibody responses in a Phase 1 clinical trial (Clinicaltrials.gov NCT02126462
Externí odkaz:
https://doaj.org/article/74b241e8340f43ffaff17b49d024c36c
Autor:
Jeannot F Zinsou, Jacqueline J Janse, Yabo Y Honpkehedji, Jean Claude Dejon-Agobé, Noemí García-Tardón, Pytsje T Hoekstra, Marguerite Massinga-Loembe, Paul L A M Corstjens, Govert J van Dam, Martin Giera, Peter G Kremsner, Maria Yazdanbakhsh, Ayola A Adegnika, Bruno Guigas
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 7, p e0008464 (2020)
Infection with parasitic helminths has been reported to improve insulin sensitivity and glucose homeostasis, lowering the risk for type 2 diabetes. However, little is known about its impact on whole-body lipid homeostasis, especially in obese individ
Externí odkaz:
https://doaj.org/article/3b352b556cda437eb34237fc11eb817d
Autor:
Sina Brückner, Selidji T Agnandji, Stefan Berberich, Emmanuel Bache, José F Fernandes, Brunhilde Schweiger, Marguerite Massinga Loembe, Thomas Engleitner, Bertrand Lell, Benjamin Mordmüller, Ayola A Adegnika, Maria Yazdanbakhsh, Peter G Kremsner, Meral Esen
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 6, p e0003768 (2015)
BACKGROUND:Helminth infections are a major public health problem, especially in the tropics. Infected individuals have an altered immune response with evidence that antibody response to vaccination is impaired. Hence, treatment of helminth infections
Externí odkaz:
https://doaj.org/article/f870a2da827d4eb9a7f4fa2623cd2fe7
Autor:
Lucja A Labuda, Sanne E de Jong, Lynn Meurs, Abena S Amoah, Moustapha Mbow, Ulysse Ateba-Ngoa, Alwin J van der Ham, André C Knulst, Maria Yazdanbakhsh, Ayola A Adegnika
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95241 (2014)
Although differences in immunological responses between populations have been found in terms of vaccine efficacy, immune responses to infections and prevalence of chronic inflammatory diseases, the mechanisms responsible for these differences are not
Externí odkaz:
https://doaj.org/article/eb20e806408548b7b673ca2b403aea12
Autor:
Lucja A Labuda, Ulysse Ateba-Ngoa, Eliane Ngoune Feugap, Jorn J Heeringa, Luciën E P M van der Vlugt, Regina B A Pires, Ludovic Mewono, Peter G Kremsner, Menno C van Zelm, Ayola A Adegnika, Maria Yazdanbakhsh, Hermelijn H Smits
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 3, p e2094 (2013)
Antibody responses are thought to play an important role in control of Schistosoma infections, yet little is known about the phenotype and function of B cells in human schistosomiasis. We set out to characterize B cell subsets and B cell responses to
Externí odkaz:
https://doaj.org/article/e26e231d4abc4bf8bed255d11d2108f4
Autor:
Luciën E P M van der Vlugt, Lucja A Labuda, Arifa Ozir-Fazalalikhan, Ellen Lievers, Anouk K Gloudemans, Kit-Yeng Liu, Tom A Barr, Tim Sparwasser, Louis Boon, Ulysse Ateba Ngoa, Eliane Ngoune Feugap, Ayola A Adegnika, Peter G Kremsner, David Gray, Maria Yazdanbakhsh, Hermelijn H Smits
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30883 (2012)
Chronic helminth infections, such as schistosomes, are negatively associated with allergic disorders. Here, using B cell IL-10-deficient mice, Schistosoma mansoni-mediated protection against experimental ovalbumin-induced allergic airway inflammation
Externí odkaz:
https://doaj.org/article/95afc997c7a54b098fe0b5c3e0f0d247